Rossi’s Principles of Transfusion Medicine, Fourth Edition

Contents......Page 6
Contributors......Page 9
Preface......Page 14
1 Transfusion in the New Millennium......Page 16
Section I. Blood Components and Derivatives......Page 30
2 Red Cell Production and Kinetics......Page 32
3 Regulation of Oxygen Delivery by Red Cells and Red Cell Substitutes......Page 44
4 Red Cell Metabolism and Preservation......Page 69
5 Red Cell Immunology and Compatibility Testing......Page 84
6 Carbohydrate Blood Groups......Page 104
7 Rh and LW Blood Group Antigens......Page 124
8 Other Protein Blood Groups......Page 136
9 Anemia and Red Blood Cell Transfusion......Page 146
10 Platelet Production, Kinetics, and Hemostasis......Page 164
11 Platelet Immunology and Alloimmunization......Page 183
12 Preparation, Preservation, and Storage of Platelet Concentrates......Page 202
13 Thrombocytopenia and Platelet Transfusion......Page 214
14 Neutrophil Production and Kinetics: Neutropenia and Neutrophilia......Page 226
15 Neutrophil Collection and Transfusion......Page 234
16 Leukocyte-Reduced Blood Components: Laboratory and Clinical Aspects......Page 243
17 Composition and Mechanisms of Blood Coagulation and Fibrinolysis......Page 262
18 Immunoglobulins......Page 275
19 Preparation of Plasma Derivatives......Page 288
20 Plasma Transfusion and Use of Albumin......Page 302
21 Applications of Cellular Radiolabeling in Transfusion Medicine......Page 313
Section II. Clinical Practice......Page 334
22 Autoimmune Hemolytic Anemia and Paroxysmal Nocturnal Hemoglobinuria......Page 336
23 Management of Immune Thrombocytopenia......Page 359
24 Bleeding from Acquired Coagulation Defects and Antithrombotic Therapy......Page 391
25 Fetal and Neonatal Hematopoiesis......Page 406
26 Obstetric Transfusion Practice......Page 421
27 Hemolytic Disease of the Fetus and Newborn......Page 433
28 Congenital Disorders of Clotting Proteins and Hypercoagulable States in Pediatrics......Page 441
29 Management of Congenital Hemolytic Anemias......Page 463
30 Blood Component Transfusions for Infants......Page 485
31 Transfusion Support for the Oncology Patient......Page 497
32 Hematopoietic Growth Factors (Cytokines)......Page 513
33 Hematopoietic Progenitor Cells: Biology and Processing......Page 523
34 Hematopoietic Progenitor Cells: Autologous Transplantation......Page 536
35 Hematopoietic Progenitor Cells: Allogeneic Transplantation......Page 557
36 Umbilical Cord Blood: A Reliable Source of Stem and Progenitor Cells for Human Transplantation......Page 574
37 Alternatives to Transfusion: Perioperative Blood Management......Page 581
38 Blood Components to Achieve Hemostasis for Surgery and Invasive Procedures......Page 590
39 Transfusion Therapy in the Care of Trauma and Burn Patients......Page 604
40 Transfusion Therapy in Solid-Organ Transplantation......Page 619
Section III. Apheresis......Page 630
41 Apheresis: Principles and Technology of Hemapheresis......Page 632
42 Therapeutic Plasma Exchange......Page 644
43 Specialized Therapeutic Hemapheresis and Phlebotomy......Page 667
Section IV. Hazards of Transfusion......Page 696
44 Overview of Hemovigilance......Page 698
45 Immunomodulatory and Proinflammatory Effects of Allogeneic Blood Transfusion......Page 714
46 Transfusion-Transmitted Hepatitis......Page 733
47 Retroviruses and Other Viruses......Page 761
48 Transfusion Transmission of Parasites......Page 775
49 Bacterial Contamination of Blood Products......Page 788
50 Prion Diseases......Page 806
51 Pathogen Inactivation......Page 816
52 Hemolytic Transfusion Reactions......Page 826
53 Febrile, Allergic, and Nonimmune Transfusion Reactions......Page 841
54 Transfusion-Associated Graft-vs-Host Disease......Page 862
55 Transfusional Iron Overload......Page 873
56 Transfusion-Related Acute Lung Injury......Page 885
Section V. Cell and Tissue Therapy......Page 900
57 HLA Antigens and Alleles......Page 902
58 Tissue Banking......Page 913
59 Adoptive Immunotherapy......Page 935
60 Gene Therapy in Transfusion Medicine......Page 951
61 Tissue Engineering and Regenerative Medicine......Page 965
Section VI. Delivery of Transfusion and Transplantation Services......Page 988
62 Recruitment and Screening of Donors and the Collection, Processing, and Testing of Blood......Page 990
63 Current Legal Issues in Transfusion Medicine......Page 1008
64 Current Good Manufacturing Practice......Page 1025
65 Transplant Organizations and Networks in the Regulation of Cellular Therapy Programs......Page 1047
66 Hospital Transfusion Committee and Quality Assurance......Page 1056
A......Page 1076
B......Page 1079
C......Page 1081
D......Page 1084
E......Page 1085
F......Page 1086
G......Page 1088
H......Page 1089
I......Page 1093
L......Page 1095
M......Page 1096
N......Page 1098
P......Page 1099
R......Page 1103
S......Page 1105
T......Page 1107
U......Page 1109
Z......Page 1110