Research in Computational Molecular Biology: 20th Annual Conference, RECOMB 2016, Santa Monica, CA, USA, April 17-21, 2016, Proceedings

Front Matter....Pages I-XXXIV
Front Matter....Pages 1-1
The Second Decade of the International Conference on Research in Computational Molecular Biology (RECOMB)....Pages 3-16
Front Matter....Pages 17-17
A MAD-Bayes Algorithm for State-Space Inference and Clustering with Application to Querying Large Collections of ChIP-Seq Data Sets....Pages 19-36
Accurate Recovery of Ribosome Positions Reveals Slow Translation of Wobble-Pairing Codons in Yeast....Pages 37-52
Multitask Matrix Completion for Learning Protein Interactions Across Diseases....Pages 53-64
pathTiMEx: Joint Inference of Mutually Exclusive Cancer Pathways and Their Dependencies in Tumor Progression....Pages 65-82
Clonality Inference from Single Tumor Samples Using Low Coverage Sequence Data....Pages 83-94
Flexible Modelling of Genetic Effects on Function-Valued Traits....Pages 95-110
MetaFlow: Metagenomic Profiling Based on Whole-Genome Coverage Analysis with Min-Cost Flows....Pages 111-121
LUTE (Local Unpruned Tuple Expansion): Accurate Continuously Flexible Protein Design with General Energy Functions and Rigid-rotamer-like Efficiency....Pages 122-136
Improving Bloom Filter Performance on Sequence Data Using  \\(k\\) -mer Bloom Filters....Pages 137-151
Safe and Complete Contig Assembly Via Omnitigs....Pages 152-163
Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants....Pages 164-175
Structural Variation Detection with Read Pair Information—An Improved Null-Hypothesis Reduces Bias....Pages 176-188
On Computing Breakpoint Distances for Genomes with Duplicate Genes....Pages 189-203
New Genome Similarity Measures Based on Conserved Gene Adjacencies....Pages 204-224
Fast Phylogenetic Biodiversity Computations Under a Non-uniform Random Distribution....Pages 225-236
Back Matter....Pages 237-274