Recombinant Glycoprotein Production

Front Matter ....Pages i-xi
 Platforms for Recombinant Therapeutic Glycoprotein Production  (Amanda Mizukami, Angelo Luis Caron, Virgínia Picanço-Castro, Kamilla Swiech)....Pages 1-14
 Uncovering Innovation Features and Emerging Technologies in Molecular Biology through Patent Analysis  (Cristiano Gonçalves Pereira, Geciane Silveira Porto)....Pages 15-34
Front Matter ....Pages 35-35
 Production of Full-Length Antibody by Pichia pastoris  (Adam Nylen, Ming-Tang Chen)....Pages 37-48
 Human Cells as Platform to Produce Gamma-Carboxylated Proteins  (Aline de Sousa Bomfim, Marcela Cristina Corrêa de Freitas, Dimas Tadeu Covas, Elisa Maria de Sousa Russo)....Pages 49-61
 Production of Recombinant Factor VIII in Human Cell Lines  (Daianne Maciely Carvalho Fantacini, Virgínia Picanço-Castro)....Pages 63-74
 Strategies to Suspension Serum-Free Adaptation of Mammalian Cell Lines for Recombinant Glycoprotein Production  (Angelo Luis Caron, Rafael Tagé Biaggio, Kamilla Swiech)....Pages 75-85
 Production of Recombinant Rabies Virus Glycoprotein by Insect Cells in a Single-Use Fixed-Bed Bioreactor  (Daniella C. Ventini-Monteiro, Renato M. Astray, Carlos A. Pereira)....Pages 87-94
 Cell-Free Production of Protein Biologics Within 24 H  (Challise J. Sullivan, Erik D. Pendleton, John Dresios)....Pages 95-107
 Demonstration-Scale High-Cell-Density Fermentation of Pichia pastoris  (Wan-Cang Liu, Ping Zhu)....Pages 109-116
 Large-Scale Transient Transfection of Suspension Mammalian Cells for VLP Production  (Laura Cervera, Amine A. Kamen)....Pages 117-127
 Bioreactor-Based Production of Glycoproteins in Plant Cell Suspension Cultures  (Tanja Holland, Johannes Felix Buyel)....Pages 129-146
 Fed-Batch CHO Cell Culture for Lab-Scale Antibody Production  (Yuzhou Fan, Daniel Ley, Mikael Rørdam Andersen)....Pages 147-161
 Strategies to Develop Therapeutic N- and O-Hyperglycosylated Proteins  (Agustina Gugliotta, Natalia Ceaglio, Marina Etcheverrigaray, Ricardo Kratje, Marcos Oggero)....Pages 163-181
 Expression of Glycosylated Proteins in Bacterial System and Purification by Affinity Chromatography  (Carlos Alexandre Breyer, Marcos Antonio de Oliveira, Adalberto Pessoa Jr)....Pages 183-191
Front Matter ....Pages 193-193
 Purification Methods for Recombinant Factor VIII Expressed in Human Liver SK-Hep Cells  (Vladimir Granovski, Mario Soares Abreu-Neto, Dimas Tadeu Covas)....Pages 195-202
 Purification Method for Recombinant hG-CSF by Affinity Chromatography  (Bruna Samham Archangelo, Elisa Maria de Sousa Russo)....Pages 203-209
 Microplate-Based Method for High-Throughput Screening (HTS) of Chromatographic Conditions Studies for Recombinant Protein Purification  (Rimenys J. Carvalho, Thayana A. Cruz)....Pages 211-220
 Purification and Autoactivation Method for Recombinant Coagulation Factor VII  (Vladimir Granovski, Marcela C. C. Freitas, Mario Soares Abreu-Neto, Dimas T. Covas)....Pages 221-226
Front Matter ....Pages 227-227
 Preparation of Immunoliposomes by Direct Coupling of Antibodies Based on a Thioether Bond  (Raquel Petrilli, Josimar O. Eloy, Robert J. Lee, Renata F. V. Lopez)....Pages 229-237
 Polyester-Based Nanoparticles for the Encapsulation of Monoclonal Antibodies  (Flávia Sousa, Pedro Fonte, Andreia Cruz, Patrick J. Kennedy, Inês Mendes Pinto, Bruno Sarmento)....Pages 239-253
 Polyester-Based Nanoparticles for Delivery of Therapeutic Proteins  (Pedro Fonte, Flávia Sousa, Bruno Sarmento)....Pages 255-274
 Quantification of Coagulation Factor VIII by Selective Reaction Monitoring  (Edson Galdino do Nascimento Filho, Guilherme Pauperio Lanfredi, Mário Soares Abreu-Neto, Dimas Tadeu Covas, Vitor Marcel Faça)....Pages 275-282
Back Matter ....Pages 283-285