Receptor-Receptor Interactions: A New Intramembrane Integrative Mechanism

Front Matter....Pages i-xviii
Front Matter....Pages 1-1
Interactions between Convergent Afferent Transmitter Systems....Pages 3-12
Interactions of Peptides and Monoamines in Central Neurons: Role of Second Messengers....Pages 13-22
Multiple Transduction Mechanisms for Dopamine D2 Receptors in Anterior Pituitary Cells....Pages 23-35
Receptor Reserves at α2-adrenergic and Dopaminergic Autoreceptors....Pages 36-42
Potentiation of NGF-mediated Effects of Laminin....Pages 44-53
Gangliosides as Modulators of Neuronotrophic Interactions....Pages 54-61
Influence of Gangliosides and Nerve Growth Factor on the Plasticity of Forebrain Cholinergic Neurons....Pages 62-77
Hippocampal Stimulation of Cholinergic Expression in Primary Cultures of Basal Forebrain Neurons....Pages 78-87
Neurosteroids: Pregnenolone and Dehydroepiandrosterone in the Brain....Pages 89-104
Estrogenic and Antiestrogenic Modulation of Neuronal Membrane Sensitivity....Pages 105-118
Effects of Estrogens on the Electrophysiological Properties of Neurons and Adenohypophyseal Cells: Interactions with Dopamine....Pages 119-130
Front Matter....Pages 131-131
Receptor Modification and Receptor Disposition in Membranes....Pages 133-144
Membrane Phospholipid Metabolism and Transmitters....Pages 145-161
Allosteric Sites and Conformational Transitions of the Acetylcholine Receptor: Models for Short-term Regulation of Receptor Response....Pages 162-190
Chloride Channel Modulation at GABAergic Synapses in Primary Cultures of Cortical Neurons....Pages 191-199
Mechanisms of Receptor-coupled Signal Transduction....Pages 200-211
The Gi-protein as a Target for Receptor-Receptor Interactions....Pages 212-220
On the Role of Receptor-Receptor Interactions in Synaptic Transmission: Biochemical and Autoradiographical Studies on the Interactions between α2-adrenergic and Neuropeptide Y Receptors in the Nucleus Tractus Solitarius....Pages 222-235
Aspects on the Integrative Capabilities of the Central Nervous System: Evidence for ‘Volume Transmission’ and its Possible Relevance for Receptor-Receptor Interactions....Pages 236-249
Radioautographic Approaches to the Study of Receptor-Receptor Interactions in the Central Nervous System....Pages 250-259
Front Matter....Pages 131-131
Long-term Receptor Regulation Induced by Denervation of Heterologous Afferent Fibers: Functional Significance....Pages 260-271
Interactions between Vasoactive Intestinal Peptide and Norepinephrine, Ergot Alkaloids and Prostanoids in Mouse Cerebral Cortex....Pages 272-283
Multiple Transduction Mechanisms Activated by the Neuropeptide Somatostatin....Pages 285-297
Receptor Mediated Activation of Phospholipase A2: Arachidonic Acid and its Metabolites as Second Messengers....Pages 298-307
Interactions between the Modulator Adenosine and Classical Transmitters....Pages 308-317
Interactions between Neuropeptide Y and Noradrenaline Receptor Mechanisms in Sympathetic Vascular Control....Pages 318-336
New Paradigm: Autonomic Neurotransmission by Multiple Interaction between Sites Intermittently Secreting Single Mixed Quanta....Pages 337-346
Adenosine Triphosphate: ‘Pre-transmitter’, Co-transmitter or Modulator at the Skeletal Muscle?....Pages 347-359
Front Matter....Pages 361-361
Multiple Signal in GABAergic Transmission: A New Family of Modulatory Peptides....Pages 363-371
Different Presynaptic Receptors Modulate Neuronal Uptake and Transmitter Release in Serotoninergic Nerve Terminals....Pages 373-386
Serotonin/Norepinephrine Receptor Interactions: Sensitivity Changes after Antidepressants and Lesions....Pages 387-397
Receptor Interactions in Antidepressant Neurochemical Mechanisms: Modulation by Membrane Components....Pages 398-406
Interactions of Coexisting Neurotransmitters and Effects of Chronic Drug Treatment....Pages 407-417
Are Opiates Involved in the Adaptation Processes of Dopamine Receptors that Follow Chronic Drug Exposure?....Pages 418-428
GABA Receptors, Depression and Antidepressant Drug Action....Pages 429-442
Front Matter....Pages 443-443
Receptor-Receptor Interactions Mediated by Protein Phosphorylation....Pages 444-453
The Molecular Logic of Presynaptic Facilitation and Inhibition....Pages 454-483
Control of Plasma Membrane Transducing Systems by Second Messengers and by Cellular Metabolism....Pages 484-493
Front Matter....Pages 495-495
The Relationships of Receptors for Phencyclidine and Sigma Opiates in Rat Cerebellum: An Electrophysiological Analysis....Pages 497-506
Modulation of Synaptic Potentials in situ by Specific Agonists of Excitatory Amino Acids....Pages 507-517
Front Matter....Pages 495-495
On the Role of Receptor-Receptor Interactions in Central Cardiovascular Regulation: Functional Studies on the Interactions between α2-adrenergic and Neuropeptide Y Receptors in the Rat Medulla Oblongata....Pages 519-530
Behavioral Analysis of the Functional Significance of Peptide-Transmitter Coexistences....Pages 531-544
Receptor Regulation and Receptor-Receptor Communication....Pages 546-554
Back Matter....Pages 555-561