Radiolabeled Blood Elements: Recent Advances in Techniques and Applications

Front Matter....Pages i-xii
Advances in Blood Cell Labeling: Pretargeting....Pages 1-5
A New Direct Method of Cell-Labeling in Whole Blood by Administration of 111In Labeled Anti-Sense Oligonucleotide Probe: Evaluation of Radiolabeled Probes for Noninvasive Imaging of Inflammation and Infection....Pages 7-13
Transchelation of 114mIn from IgG-DTPA to Abscess-Related Proteins....Pages 15-18
The Antibody Approach of Labeling Blood Cells....Pages 19-27
Quality Control of Radiolabelled White Cells....Pages 29-32
Granulocyte Cell Labeling with TcN-NOET....Pages 33-37
Arteriosclerosis and Monocyte-Adhesion in Vivo ....Pages 39-42
Stabilization of Exametazime for Leucocyte Labelling: A New Approach using Tin Enhancement....Pages 43-48
99mTc Labelling of Interleukin-2 for in Vivo Targeting of Activated T-Lymphocytes....Pages 49-52
Nitric Oxide and Prostaglandin I 2 for Radiolabelling of Human Platelets....Pages 53-60
111In Labeling of Human IgG using a DTPA-IgG Kit....Pages 61-65
Quantitation of Platelet Consumption in Health and Disease....Pages 67-90
Platelet Labeling Parameters are Influenced by Lipids and Lipoproteins*....Pages 91-98
Clinical Applications of 111In-Tropolonate Labelled Platelets....Pages 99-106
Platelet-Emboli from Arterial Filter and Oxygenator: Major Source of Embolic Complications During Cardiopulmonary Bypass (CPB)....Pages 107-113
The Fate of Emboli Post-Recanalization of Thrombus-Occluded Artery and Vein in Yorkshire Pigs....Pages 115-119
Direct Method of Quantitation of Platelet-Embolus and Residence Time in Brain with Radiolabeled Platelets Formed by Photodenudation of Endothelial Cells of Carotid Artery in a Rat Model....Pages 121-126
Multicompartmental Computer Analysis of 111In-Tropolone Labelled Blood Platelet Kinetic Data in Normal Humans....Pages 127-130
Influence of Platelet Membrane Sialic Acid and Platelet Associated IgG on Ageing and Sequestration of Blood Platelets in Baboons....Pages 131-134
Uptake of Radiolabeled Meta-Iodobenzylguanidine by Human Platelets....Pages 135-139
Granulocyte Kinetics....Pages 141-145
Experiences in Immunoscintigraphy of Leukocytes....Pages 147-160
In Vitro and in Vivo Comparison of Some Properties of Antigranulocyte Antibodies....Pages 161-165
Antigenicity of Different Antigranulocytes Antibodies Assessed By Hama Follow-Up In Patients Undergoing Immunoscintigraphic Detection of Infections....Pages 167-171
111in-Polyclonal IgG and 125I-LDL Accumulation in Experimental Arterial Wall Injury....Pages 173-175
Radiation Induced Chromosomal Damage to Lymphocytes in Usual 99mTc-HMPAO Leukocyte Preparations....Pages 177-182
Radiobiologic Study of 99mTc-HMPAO Labelled Lymphocytes....Pages 183-185
Peptides and Proteins in Radiolabeling of Blood Elements....Pages 187-194
Peptides in Biomedical Sciences: Principles and Practice....Pages 195-199
Molecular Recognition Units (MRUs) and the Imaging of Human Disease....Pages 201-205
Techniques for Direct Radiolabeling of Monoclonal Antibodies....Pages 207-220
Lipoprotein Labeling and Analysis Techniques....Pages 221-230
111In Antifibrin Monoclonal Antibodies in the Evaluation of the Deep Venous Thrombosis of the Lower Limbs: An Italian Multicenter Study....Pages 231-234
Interactions of Blood Cells with the Vessel Wall....Pages 235-239
Is 111In-Leucocyte Scintigraphy Useful in the Evaluation of Patients with Prolonged Fever of Unknown Origin?....Pages 241-245
Diagnosis of Inflammatory Bone and Joint Diseases with Monoclonal Antibodies (BW 250/183)....Pages 247-249
Imaging Inflammatory Bowel Disease....Pages 251-256
Fast Diagnosis of Abdominal Infections and Inflammatory Bowel Disease with 99mTc-HMPAO Leukocyte Scan....Pages 257-260
111In Labeled Lymphocyte Scintigraphy in Patients with Malignant Lymphoma....Pages 261-265
In Vivo Detection of Lymphocytic Infiltration: Present Status and New Prospects....Pages 267-271
Clinical Experiences with 111In Labeled Human Polyclonal IgG....Pages 273-277
Comparison of Technetium-99m-Labelled Human Polyclonal Immunoglobulin Scintigraphy with Conventional Bone Scintigraphy in Patients with Rheumatoid Arthritis and Osteoarthritis....Pages 279-281
Antigranulocyte Antibody Bone Marrow Scans in Cancer Patients with Metastatic Bone Superscan Appearance....Pages 283-285
Imaging of RA Inflamed Joints with 99mTc-Labeled Specific Murine Anti-CD4- and Nonspecific Human Immunoglobulin....Pages 287-294
99mTc-Hmpao Radiolabelled Leucocytes in Inflammatory Bowel Disease: Spect Vs Planar Scintigraphy....Pages 295-299
First Year Evolutionary Patterns of 99mTc-HMPAO-Leukocyte Uptake in Uneventful Prosthetic Knee Joint Replacement....Pages 301-305
Detection and Quantitative Analysis of Joint Inflammation With 99mTc-Polyclonal Human Immunoglobulin G....Pages 307-310
Increased Lung Activity of 111In Labelled Polyclonal IgG in Patients with Aids and Active Chest Infection....Pages 311-314
111In-Platelets and 99mTc-Human Polyclonal Immunoglobulin (HIG) Scintigraphy in Patients with Cerebrovascular Disease....Pages 315-320
Diagnosis of Vascular Graft Infection by 99mTc-HMPAO-Labeled Leukocyte Scan....Pages 321-324
Labeled Platelets in Idiopathic Thrombocytopenic Purpura....Pages 325-329
Clinical Role of Radionuclide Based Technology for Thrombus Imaging in 1992....Pages 331-333
Clinical Applications of Radiolabeled Platelets: Kidney and Pancreas Transplantation....Pages 335-338
111In-Antimyosin Antibodies for Detection of Heart Transplant Rejection....Pages 339-342
Dose-Dependent Inhibition of Acute Arterial Thrombosis by Monoclonal Antibody (16N7C2) in a Baboon Model....Pages 343-347
HIV-Related Thrombocytopenia: Four Different Clinical Subsets....Pages 349-353
68Ga MPO Platelets in Human Pet Thrombus Imaging....Pages 355-362
Back Matter....Pages 363-370