Pulsatility in Neuroendocrine Systems

Content: 
Methods in Neurosciences
Page ii

Front Matter
Page iii

Copyright page
Page iv

Contributors to Volume 20
Pages ix-xiii

Preface
Pages xv-xvi
JON E. LEVINE

Methods in Neurosciences
Pages xvii-xviii

1 - Analysis of Pulsatility in Immortalized GnRH Cell Lines
Pages 3-12
Gonzalo Martinez de la Escalera, Richard I. Weiner

2 - Use of Organotypic Cultures for the Study of Neuroendocrine Cells
Pages 13-44
Susan Wray

3 - Electrophysiological Analysis of Neuroendocrine Neuronal Activity in Hypothalamic Slices
Pages 47-67
Martin J. Kelly, Oline K. Rønnekleiv

4 - Calcium Signaling and Episodic Secretory Responses of GnRH Neurons
Pages 68-84
Stanko S. Stojilkovic, Lazar Z. Krsmanovic, Daniel J. Spergel, Melanija Tomic, Kevin J. Catt

5 - Patch-Clamp Studies on Identified Pituitary Gonadotropes in Vitro
Pages 85-99
Amy Tse, Bertil Hille

6 - Electrophysiological Analysis of GnRH Pulse Generator Activity in the Rhesus Monkey
Pages 100-113
Kevin T. O\'Byrne, Ernst Knobil

7 - In Vivo Electrophysiological Monitoring of the GnRH Pulse Generator in Rats and Goats
Pages 114-126
Masugi Nishihara, Yuji Mori, Mi-Jeong Yoo, Michio Takahashi

8 - In Vivo Sampling and Administration of Hormone Pulses in Rodents
Pages 129-161
Jon E. Levine, Andrew M. Wolfe, Tarja Porkka-Heiskanen, John M. Meredith, Jeffrey R. Norgle, Fred W. Turek

9 - Sampling of Hypophyseal Portal Blood of Conscious Sheep for Direct Monitoring of Hypothalamic Neurosecretory Substances
Pages 162-183
Alain Caraty, Alain Locatelli, Suzanne M. Moenter, Fred J. Karsch

10 - In Vivo Measurement of Pulsatile Release of Neuropeptides and Neurotransmitters in Rhesus Monkeys Using Push–Pull Perfusion
Pages 184-202
Ei Terasawa

11 - In Vitro Systems for Modeling Target Tissue Responses to Secretory Pulses of the Islet Hormones: Glucagon and Insulin
Pages 203-229
Charles J. Goodner

12 - Pulsatile Endocrine Secretion in the Ovine Fetus
Pages 230-246
Steven M. Yellon, Ede M. Apostolakis

13 - Pulsatile Corticosterone Secretion as Measured by Intraadrenal Microdialysis
Pages 247-264
Michael S. Jasper, Jill T. Walworth, William C. Engeland

14 - Comparative Analysis and Procedures for Validation of Pulse-Detection Algorithms
Pages 267-278
Randall J. Urban

15 - Deconvolution Analysis of Neuroendocrine Data: Waveform-Specific and Waveform-Independent Methods and Applications
Pages 279-325
Johannes D. Veldhuis, John Moorman, Michael L. Johnson

16 - Analysis of the Temporal Coincidence of Hormonal Pulses
Pages 326-335
George R. Merriam, Kenneth W. Wachter

17 - Assessing Temporal Coupling between Two or among Three or More Neuroendocrine Pulse Trains
Pages 336-376
Johannes D. Veldhuis, Michael L. Johnson, Lindsay M. Faunt, Eugene Seneta

18 - Estimating Thyrotropin Secretory Activity by a Deconvolution Procedure
Pages 377-390
Klaus Prank, Georg Brabant

19 - Modeling Modulatory Effects on Pulsatility
Pages 393-422
Jeppe Sturis, Erik Mosekilde, Eve Van Cauter

20 - Modeling Pulsatile Hormone Stimulation of Cell Responses
Pages 423-442
Rosalind P. Murray-Mclntosh, James Edward Alister McIntosh

21 - Pulsatile Neuropeptide Delivery and Analysis of Hormone Biosynthesis
Pages 445-465
Margaret A. Shupnik

22 - Use of an in Vitro Perifusion System to Study the Effects of Pulsatile Hormone Administration on the Control of the Hypothalamic–Pituitary–Ovarian Axis
Pages 466-487
Jacqueline F. Ackland, Kerry L. Knox, Adria A. Elskus, Patricia C. Fallest, Eve S. Hiatt, Neena B. Schwartz

23 - Pulsatile Administration of Insulin and Glucagon in Man
Pages 488-499
Pierre J. Lefèbvre, Giuseppe Paolisso, André J. Scheen

Index
Pages 501-510