Proteolytic Enzymes in Coagulation, Fibrinolysis, and Complement Activation Part A: Mammalian Blood Coagulation Factors and Inhibitors

Content: 
Contributors to volume 222
Pages ix-xi

Preface
Page xiii
Laszlo Lorand, Kenneth G. Mann

Volumes in series
Pages xv-xxviii

Introduction: Blood coagulation
Pages 1-10
Kenneth G. Mann, Laszlo Lorand

[1] Modular design of proteases of coagulation, fibrinolysis, and complement activation: Implications for protein engineering and structure-function studies Original Research Article
Pages 10-21
LГЎszlГі Patthy

[2] Human plasma factor XIII: Subunit interactions and activation of zymogen Original Research Article
Pages 22-35
Laszlo Lorand, Jong-Moon Jeong, James T. Radek, James Wilson

[3] Molecular approach to structure-function relationship of human coagulation factor XIII Original Research Article
Pages 36-51
Akitada Ichinose, Hiroshi Kaetsu

[4] Factor XII: Hageman factor Original Research Article
Pages 51-65
Robin A. Pixley, Robert W. Colman

[5] Factor XI: Structure-function relationships utilizing monoclonal antibodies, protein modification, computational chemistry, and rational synthetic peptide design Original Research Article
Pages 65-96
Peter N. Walsh, Frank A. Baglia, Bradford A. Jameson

[6] Human factor IX and factor IXa Original Research Article
Pages 96-128
S.Paul Bajaj, Jens J. Birktoft

[7] Factor VIII and factor VIIIa Original Research Article
Pages 128-143
Pete Lollar, Philip J. Fay, David N. Fass

[8] Characterization of factor IX defects in hemophilia B patients Original Research Article
Pages 143-169
Arthur R. Thompson, Shi-Han Chen

[9] Characterization of dysfunctional factor VIII molecules Original Research Article
Pages 169-176
Leon W. Hoyer

[10] Extrinsic pathway proteolytic activity Original Research Article
Pages 177-195
Jeffrey H. Lawson, Sriram Krishnaswamy, Saulius Butenas, Kenneth G. Mann

[11] Tissue factor pathway inhibitor Original Research Article
Pages 195-209
Thomas J. Girard, George J. Broze Jr.

[12] Mutational analysis of receptor and cofactor function of tissue factor Original Research Article
Pages 209-224
Wolfram Ruf, David J. Miles, Alnawaz Rehemtulla, Thomas S. Edgington

[13] Factor V Original Research Article
Pages 224-236
Michael Kalafatis, Sriram Krishnaswamy, Matthew D. Rand, Kenneth G. Mann

[14] Site-directed mutagenesis and expression of coagulation factors VIII and V in mammalian cells Original Research Article
Pages 236-260
Debra D. Pittman, Randal J. Kaufman

[15] Assembly of prothrombinase complex Original Research Article
Pages 260-280
Sriram Krishnaswamy, Michael E. Nesheim, Edward L.G. Pryzdial, Kenneth G. Mann

[16] Procoagulant activities expressed by peripheral blood mononuclear cells Original Research Article
Pages 281-299
Paula B. Tracy, Royce A. Robinson, Laura A. Worfolk, Debra H. Allen

[17] Meizothrombin: Active intermediate formed during prothrombinase-catalyzed activation of prothrombin Original Research Article
Pages 299-312
Margaret F. Doyle, Paul E. Haley

[18] Identification and characterization of mutant thrombins Original Research Article
Pages 312-327
Ruth Ann Henriksen

[19] Synthetic selective inhibitors of thrombin Original Research Article
Pages 328-340
Shosuke Okamoto, Akiko Hijikata-Okunomiya

[20] Quantifying thrombin-catalyzed release of fibrinopeptides from fibrinogen using high-performance liquid chromatography Original Research Article
Pages 341-358
Assunta S. Ng, Sidney D. Lewis, Jules A. Shafer

[21] Protein C activation Original Research Article
Pages 359-385
Charles T. Esmon, Naomi L. Esmon, Bernard F. Le Bonniec, Arthur E. Johnson

[22] Protein C inhibitor Original Research Article
Pages 385-399
Koji Suzuki

[23] Immunochemical techniques for studying coagulation proteins Original Research Article
Pages 400-416
Richard J. Jenny, Terri L. Messier, Laurie A. Ouellette, William R. Church

[24] Isolation of intact modules from noncatalytic parts of vitamin K-dependent coagulation factors IX and X and protein C Original Research Article
Pages 416-435
Carmen Valcarce, Egon Persson, Jan Astermark, Ann-Kristin Г–hlin, Johan Stenflo

[25] Role of propeptide in vitamin K-dependent Оі-carboxylation Original Research Article
Pages 435-449
Karen J. Kotkow, David A. Roth, Thomas J. Porter, Barbara C. Furie, Bruce Furie

[26] Expression of recombinant vitamin K-dependent proteins in mammalian cells: Factors IX and VII Original Research Article
Pages 450-477
Kathleen L. Berkner

[27] Thioester peptide chloromethyl ketones: Reagents for active site-selective labeling of serine proteinases with spectroscopic probes Original Research Article
Pages 478-503
Paul E. Bock

[28] Peptide chloromethyl ketones as labeling reagents Original Research Article
Pages 503-513
E.Brady Williams, Kenneth G. Mann

[29] Active site-specific assays for enzymes of coagulation and fibrinolytic pathways Original Research Article
Pages 514-525
Russell P. Tracy, Richard Jenny, E.Brady Williams, Kenneth G. Mann

[30] Kinetic characterization of heparin-catalyzed and uncatalyzed inhibition of blood coagulation proteinases by antithrombin Original Research Article
Pages 525-559
Steven T. Olson, Ingemar Björk, Joseph D. Shore

Author index
Pages 561-588

Subject index
Pages 589-613