Protein Prenylation Part B

Content: 
Copyright
Page iv

Preface
Pages xi-xii

Chapter 1 - The Enzymology of CAAX Protein Prenylation
Pages 1-11
Kendra E. Hightower, Patrick J. Casey

Chapter 2 - CAAX Processing and Yeast a-Factor Biogenesis
Pages 13-41
Jemima Barrowman, Susan Michaelis

Chapter 3 - Prenylation and Phosphorylation of Ras Superfamily Small GTPases
Pages 43-69
Heather B. Hodges-Loaiza, Lauren E. Parker, Adrienne D. Cox

Chapter 4 - Biochemical and Biological Functions of Isoprenylcysteine Carboxyl Methyltransferase
Pages 71-90
Helen Court, Kalub Hahne, Mark R. Philips, Christine A. Hrycyna

Chapter 5 - Chemical Probes of Protein Prenylation
Pages 91-127
Andrew T. Placzek, Amanda J. Krzysiak, Richard A. Gibbs

Chapter 6 - Geranylgeranyltransferase-1 Inhibitors
Pages 129-163
Norbert Berndt, Andrew D. Hamilton, Saïd M. Sebti

Chapter 7 - Small-Molecule Inhibitors of GGTase-I from the Heterocycle Library Derived from Phosphine Catalysis
Pages 165-177
Lai N. Chan, Masaru Watanabe, Ohyun Kwon, Fuyuhiko Tamanoi

Chapter 8 - Inhibition of Rab Prenylation
Pages 179-203
E. Anouk Stigter, Gemma Triola, Roger S. Goody, Herbert Waldmann

Chapter 9 - Inhibitors of Postprenylation CAAX Processing Enzymes
Pages 205-229
Joel A. Bergman, Jaimeen D. Majmudar, Richard A. Gibbs, Christine A. Hrycyna

Chapter 10 - The Ras Converting Enzyme (Rce1p): Orthologs, Enzymology, and Inhibitors
Pages 231-258
Walter K. Schmidt, Timothy M. Dore

Chapter 11 - Cysmethynil, a Specific Small-Molecule Inhibitor of Isoprenylcysteine Carboxylmethyl Transferase (Icmt)
Pages 259-278
Mei Wang

Chapter 12 - The Isoprenoid Biosynthetic Pathway and Statins
Pages 279-299
Sarah A. Holstein

Chapter 13 - Inhibition of Farnesyl and Geranylgeranyl Diphosphate Synthases
Pages 301-319
Sarah A. Holstein, Raymond J. Hohl

Author Index
Pages 321-352

Index
Pages 353-359