Protein Biosynthesis in Eukaryotes

Front Matter....Pages i-xviii
Front Matter....Pages xix-xix
Structure and Function of tRNA and Aminoacyl tRNA Synthetases in Eukaryotes....Pages 1-67
The Structure of Eukaryotic Ribosomes....Pages 69-95
The Initiation Factors....Pages 97-117
Front Matter....Pages N1-N1
Messenger RNA Structure and Biosynthesis....Pages 119-135
SV4O as a Model System for the Study of RNA Transcription and Processing in Eukaryotic Cells....Pages 137-156
Messenger Ribonucleoprotein Particles....Pages 157-166
Front Matter....Pages N3-N3
Recognition of Initiation Sites in Eukaryotic Messenger RNAs....Pages 167-197
A Closer Look at the 5′-End of mRNA in Relation to Initiation....Pages 199-221
Initiation Factor/mRNA Interactions and mRNA Recognition....Pages 223-243
But is the 5′ End of Messenger RNA Always Involved in Initiation?....Pages 245-252
Front Matter....Pages N5-N5
Peptide Chain Elongation and Termination in Eukaryotes....Pages 253-273
Biosynthesis, Modification and Processing of Viral Polyproteins....Pages 275-309
Front Matter....Pages N7-N7
Action of Inhibitors of Protein Biosynthesis....Pages 311-337
Virus-Induced Shut-Off of Host Specific Protein Synthesis....Pages 339-361
Front Matter....Pages N9-N9
The Cytoplasmic Control of Protein Synthesis....Pages 363-418
Regulation of eIF-2 Activity and Initiation of Protein Synthesis in Mammalian Cells....Pages 419-440
Messenger RNA Competttion....Pages 441-457
Interferon Action: Control of RNA Processing, Translation and Degradation....Pages 459-483
Back Matter....Pages 485-501