Proof of Therapeutical Effectiveness of Nootropic and Vasoactive Drugs: Advances in Clinical and Experimental Nicergoline Research

Front Matter....Pages I-XI
Front Matter....Pages 1-1
Principles of Controlled Clinical Studies in Psychogeriatrics....Pages 3-15
Prognosis of Cerebrovascular Disease....Pages 17-22
Front Matter....Pages 23-23
Promoting Vigilance in Older People: Comparative Pharmaco-EEG and Psychometric Studies with Nicergoline by Oral and Intramuscular Administration....Pages 25-44
Correlation Between Computerized EEG and Clinical Findings in Patients with Senile Dementia....Pages 45-50
A Placebo-Controlled Study with Nicergoline in Patients with Organic Brain Syndrome, Suffering from Cochlear and Vestibular Disturbances....Pages 51-58
Front Matter....Pages 59-59
Neurotransmitter Alterations in the Aging Brain....Pages 61-101
Neurochemical Effects of Ergoline Derivatives....Pages 103-110
Pharmacological Intervention on Some Enzyme Activities of Various Brain Areas During Hypoxia and Post-Hypoxic Recovery....Pages 111-118
The Effects of Nicergoline and Other Vaso-Active Substances on Molecular Biological Processes in the Brain and Their Effects on the Learning Abilities of Rats....Pages 119-130
Front Matter....Pages 131-131
Salutary Actions of Nicergoline During Experimental Coronary Artery Occlusion and Reperfusion....Pages 133-147
Front Matter....Pages 149-149
A General Introduction to Haemorrheology and its Clinical Importance....Pages 151-158
Effects of a Single I.V. Dose of Nicergoline on Haemorrheological and Haemodynamic Parameters in Peripheral Vascular Disease. A Double-Blind, Cross-over Study....Pages 159-168
The Effects of Nicergoline on the Filtrability of Hyperosmolar Blood....Pages 169-172
Influence of Nicergoline on Platelet Aggregation and Erythrocyte Filterability....Pages 173-184
Front Matter....Pages 185-185
Nicergoline Injectable in the Treatment of Cochlear Emergencies....Pages 187-194
Long-Term Study with Nicergoline in Ophthalmological Practice....Pages 195-202
Front Matter....Pages 203-203
Transitory Ischaemic Attacks and Their Treatment with Nicergoline....Pages 205-214
Methodological Approach to the Clinical Evaluation of Nootropic Drugs....Pages 215-222
Front Matter....Pages 223-223
Haemodynamic and Metabolic Effects of Nicergoline in Healthy and Arteritic Patients at Rest or During Exercise....Pages 225-232
Front Matter....Pages 233-233
Nicergoline and Impaired Brain Function. Results of a One-Year Clinical Trial....Pages 235-253
Back Matter....Pages 255-258