Principles of food toxicology

Basics of Toxicology Connected to Food   Introduction  What is Toxicology?  Short History of Toxicology  Toxicity, Dose, and Response Integrated Effect of Toxic Substances  Classification of Toxicants Some Toxicology-Related Principles of Basics of Cell Biology and Biochemistry  References   Routes of Xenobiotics in an Organism  Entry and Absorption of Foreign Substances  Distribution of Xenobiotics in an Organism  Metabolism of Xenobiotics  Elimination of Xenobiotics and their Metabolites from Organism  Biomagnification  Antidotes  References   Toxic Response  Variability in Toxic Response  Physiological Classification of Toxic Responses  Molecular Mechanisms of Toxicity Biomarkers of Toxic Effect References    Analytical Toxicology: Determination of Foreign Compounds  Introduction  Sample Preparation  Mouse Bioassay: Functional Analysis Biological Methods: Biosensors Immunochemical Methods: Immunosensors . Spectrophotometric (Colorimetric) Methods    Electrophoretic Methods  Chromatographic Methods Detectors    References   Evaluation of Toxicity of Substances  Epidemiological Studies  Animal Tests  Cell-Culture Tests-Elaboration of Alternative Methods Computer Calculations  Acute Toxicity Tests  Subacute/Chronic Toxicity Tests  Chronic Toxicity Tests Specific Toxicity Tests  References  Toxicological Safety and Risk Analysis Toxicological Safety  Risk Assessment  Risk.Benefit Analysis References   MAIN GROUPS OF FOOD-BORNE TOXICANTS  Endogenous Plant Toxicants  Lectins or Hemagglutinins Enzyme Inhibitors Alkaloids  Cyanogenic Glycosides. Toxicity Mechanisms of HCN Phytoestrogens  Glucosinolates  Coumarin  Thujones  Toxic Amino Acids  Toxic Lipids  Oxalates  Fluoroacetates  Bracken Toxins  Saponins  Grayanotoxin  Soybean as a Potential Source of Versatile Toxicants  Mushroom Toxins  Miscelleaneous  Genetically Modified Plants  References   Geochemical Pollutants that Plants Absorb from Soil  Arsenic  Selenium  Fluorine  References   Environmental Pollutants  Toxic Elements  Radionuclides  Polychlorinated Biphenyls (PCB)  Polychlorinated Dibenzodioxins and Dibenzofurans  References   Mycotoxins  Overview  Aflatoxins  Ochratoxins  Sterigmatocystin  Zearalenone  Fumonisins  Trichothecenes  Patulin  Citrinin and Citreoviridin  Ergot Toxins  Other Mycotoxins  Combined Toxicity of Mycotoxins  References   Animal Endogenous Poisons  Prions  Lactose  Phytanic Acid  Avidin  Vitamins of Animal Origin  References   Food Toxicants from Aquatic Animals Shellfish Toxicants  Fish Toxins  References   Pesticide Residues  Overview Insecticides  Herbicides  Fungicides  References  Veterinary Drugs and Feed Additives  Antibiotics  Hormones  Other Veterinary Drugs  References   Toxicants Unintentionally Entering Food During Processing, Storage, and Digestion of Food General  Polycyclic Aromatic Hydrocarbons  Alcohols  Bacterial toxins  Biogenic Vasoactive Amines  Nitrates, Nitrites and Nitrosoamines  Acrylamide and 5-Hydroxymethylfurfural  Trans Fatty Acids  Toxic Oxidation Products of PUFAs  Chlorinated Propanols  Food Contact Materials  References   Food Additives  Traditional food additives  Functional additives  References   Vitamins  General  Vitamin A. Phenomenon of smokers  Vitamin D  Vitamin E  Vitamin K  Vitamin B2  Vitamin B6  Vitamin C  Vitamin B3  Diagnosing and Therapy of Vitamin Intoxications  References   Food Adulterations  What is Food Adulteration?  Melamime and Cyanuric Acid  AnisatineToxic Oil Syndrome Epidemic Dropsy References