Primary immunodeficiency disorders : a historic and scientific perspective

Content: 
Front matter, Page iii
Copyright, Page iv
Contributors, Pages vii-ix, Bernd H. Belohradsky, Melvin Berger, Aziz A. Bousfiha, Jean-Laurent Casanova, Marina Cavazzana-Calvo, Helen M. Chapel, Antonio Condino-Neto, Max D. Cooper, Charlotte Cunningham-Rundles, Robert Currier, Geneviève de Saint Basile, Carol Ann Demaret, Anne Durandy, Karin R. Engelhardt, Amos Etzioni, Alain Fischer, Thomas A. Fleisher, Michael M. Frank, Richard A. Gatti, Raif S. Geha, Bodo Grimbacher,  et al.
Foreword, Pages xi-xvii, Hans D. Ochs, Amos Etzioni
Introduction, Pages xix-xxi, Raif S. Geha
Chapter 1 - Immunity: From Serendipitous Observations to Science-Based Specialty, Pages 1-11, Hans D. Ochs
Chapter 2 - Discovery of the T- and B-Cell Compartments, Pages 13-28, Max D. Cooper
Chapter 3 - Evolution of the Definition of Primary Immunodeficiencies, Pages 29-40, Capucine Picard, Jean-Laurent Casanova
Chapter 4 - From Immunodeficiency to Autoimmunity, Pages 41-49, Luigi Daniele Notarangelo
Chapter 5 - Immunological Tests – from the Microscope to Whole Genome Analysis, Pages 51-63, Thomas A. Fleisher
Chapter 6 - Primary Immunodeficiency in the Developing Countries, Pages 65-75, Aziz A. Bousfiha, Leila Jeddane, Antonio Condino-Neto
Chapter 7 - Jeffrey Asked Us to “Do Something”! Our Journey, Pages 77-81, Vicki Modell, Fred Modell
Dates of description and gene discovery of major PIDDs, Page i
Chapter 8 - Finally Found: The Ataxia-Telangiectasia Gene and its Function, Pages 83-95, Amos Etzioni, Hans D. Ochs, Deborah McCurdy, Richard A. Gatti
Chapter 9 - Wiskott–Aldrich Syndrome: from a Fatal Hematologic Disorder to a Curable Immunodeficiency, Pages 97-109, Hans D. Ochs, Bernd H. Belohradsky
Chapter 10 - Neutropenia – More Genetic Defects Than Ever Expected, Pages 111-126, Karl Welte
Chapter 11 - B-Cell Defects: From X-linked Recessive to Autosomal Recessive Agammaglobulinemia, Pages 127-138, Jerry A. Winkelstein, C.I. Edvard Smith
Chapter 12 - The Discovery of the Familial Hemophagocytosis Syndromes, Pages 139-149, Geneviève de Saint Basile, Alain Fischer
Chapter 13 - Chronic Granulomatous Disease – from a Fatal Disease to a Curable One, Pages 151-170, Steven M. Holland
Chapter 14 - Severe Combined Immunodeficiency – from Discovery to Newborn Screening, Pages 171-180, Jennifer M. Puck, Robert Currier
Chapter 15 - Severe Combined Immunodeficiency as Diseases of Defective Cytokine Signaling, Pages 181-196, Warren J. Leonard
Chapter 16 - The Hyper IgM Syndromes – a Long List of Genes and Years of Discovery, Pages 197-216, Anne Durandy, Sven Kracker
Chapter 17 - Unraveling the Complement System and its Mechanism of Action, Pages 217-228, Michael M. Frank
Chapter 18 - DiGeorge Syndrome: A Serendipitous Discovery, Pages 229-240, Kathleen E. Sullivan, Donna M. McDonald-McGinn
Chapter 19 - The Many Faces of the Hyper-IgE Syndrome, Pages 241-254, Karin R. Engelhardt, Bodo Grimbacher
Chapter 20 - ADA Deficiency – The First Described Genetic Defect Causing PID, Pages 255-266, Michael S. Hershfield, Hilaire J. Meuwissen, Rochelle Hirschhorn
Chapter 21 - The Leukocyte Adhesion Deficiency Story, Pages 267-274, Amos Etzioni
Chapter 22 - How Common Variable Immune Deficiency has Changed Over Six Decades, Pages 275-282, Charlotte Cunningham-Rundles, Helen Chapel
Chapter 23 - From Subcutaneous to Intravenous Immunoglobulin and Back, Pages 283-297, Melvin Berger, E. Richard Stiehm
Chapter 24 - History of Hematopoietic Stem Cell Transplantation, Pages 299-312, Richard A. Gatti, Rainer Storb
Chapter 25 - David’s Story, Pages 313-326, William T. Shearer, Carol Ann Demaret
Chapter 26 - How Primary Immunodeficiencies Have Made Gene Therapy a Reality, Pages 327-339, Alain Fischer, Salima Hacein-Bey-Abina, Marina Cavazzana-Calvo
Index, Pages 341-353