Preservation of human oocytes : from crybiology science to clinical applications

 Content: Part I: Fundamental cryobiology  1. A historical overview of embryo and oocyte preservation in the world of mammalian in vitro fertilization and biotechnology  2. Principles of cryobiology  3. Rational basis of controlled rate cooling  4. Fundamentals and current practice of vitrification  5. Predictive models for the development of improved cryopreservation protocols for human oocytes Part II: Biological aspect of oocyte cryopreservation  6. Natural life cycle of the mammalian oocyte  7. Essential features of the mature oocyte  8. Expression of functional aquaporins in oocytes and embryos and the impact on cryopreservation 9. Oocyte storage at different developmental stages  10. Oocyte cyopreservation in the mouse  11. Oocyte storage in domestic species  12. Control of the solution effect during controlled rate cooling: principles and practical application  13. Cryopreservation and the cytoskeleton of the human oocyte 14. Non-invasive assessment of cryopreserved oocytes through polarized light microscopy  15. Impact of cryopreservation on oocyte physiology, metabolism and the proteome  Part III: Laboratory, clinical, and ethical aspects of oocyte storage  16. Quality management of a low temperature storage program in the human IVF laboratory  17. The contribution of embryo cryopreservation in the clinical efficacy of ART and to a reduction of ART multiple pregnancies 18. Factors influencing the clinical efficiency of oocyte cryopreservation  19. Early and recent history of oocyte cryopreservation in human IVF  20. Success rates from oocyte cryopreservation  21. Clinical evidence of oocyte vitrification  22. The impact of oocyte storage for fertility preservation before radio- and chrmotherapy 23. Impact of oocyte storage in oocyte donation treatments  24. The health of babies from cryopreserved oocytes and embryos  25. The ethics of fertility preservation