Preclinical MRI: methods and protocols

Front Matter ....Pages i-xiv
Front Matter ....Pages 1-1
 Introduction to MRI Physics  (Gary V. Martinez)....Pages 3-19
 Basic Pulse Sequences in Magnetic Resonance Imaging  (Daniel Calle, Teresa Navarro)....Pages 21-37
Front Matter ....Pages 39-39
 Dynamic Susceptibility Contrast MRI in Small Animals  (Pilar López-Larrubia)....Pages 41-57
 Preclinical Arterial Spin Labeling Measurement of Cerebral Blood Flow  (Eric R. Muir)....Pages 59-70
 Dynamic Contrast-Enhanced MRI  (Jennifer Moroz, Stefan A. Reinsberg)....Pages 71-87
 Diffusion-Weighted Magnetic Resonance Imaging  (Irene Guadilla, Daniel Calle, Pilar López-Larrubia)....Pages 89-101
 Diffusion Tensor Imaging (DTI)  (Silvia Lope-Piedrafita)....Pages 103-116
 Mapping Functional Connectivity in the Rodent Brain Using Electric-Stimulation fMRI  (Laura Pérez-Cervera, José María Caramés, Luis Miguel Fernández-Mollá, Andrea Moreno, Begoña Fernández, Elena Pérez-Montoyo et al.)....Pages 117-134
 Functional Diffusion Magnetic Resonance Imaging  (Rita Maria Rocha Oliveira, Irene Guadilla, Pilar López-Larrubia)....Pages 135-147
Front Matter ....Pages 149-149
 In Vivo 1H Magnetic Resonance Spectroscopy  (M. Carmen Muñoz-Hernández, María Luisa García-Martín)....Pages 151-167
 In Vivo Heteronuclear Magnetic Resonance Spectroscopy  (Blanca Lizarbe, Antoine Cherix, Rolf Gruetter)....Pages 169-187
 1H Spectroscopic Imaging of the Rodent Brain  (Rui V. Simões, Emma Muñoz-Moreno, Raúl Tudela, Guadalupe Soria)....Pages 189-202
Front Matter ....Pages 203-203
 Susceptibility Weighted MRI in Rodents at 9.4 T  (Ferdinand Schweser, Marilena Preda, Robert Zivadinov)....Pages 205-234
 Biomedical 19F MRI Using Perfluorocarbons  (Tuba Güden-Silber, Sebastian Temme, Christoph Jacoby, Ulrich Flögel)....Pages 235-257
 Rodent Abdominal Adipose Tissue Imaging by MR  (Bhanu Prakash KN, Jadegoud Yaligar, Sanjay K. Verma, Venkatesh Gopalan, S. Sendhil Velan)....Pages 259-268
 Cardiac MRI in Small Animals  (Min-Chi Ku, Till Huelnhagen, Thoralf Niendorf, Andreas Pohlmann)....Pages 269-284
 In Utero MRI of Mouse Embryos  (Jiangyang Zhang, Dan Wu, Daniel H. Turnbull)....Pages 285-296
 Oxygenation Imaging by Nuclear Magnetic Resonance Methods  (Heling Zhou, Nuria Arias-Ramos, Pilar López-Larrubia, Ralph P. Mason, Sebastián Cerdán, Jesús Pacheco-Torres)....Pages 297-313
 Molecular Magnetic Resonance Imaging (mMRI)  (Maxime Gauberti, Antoine P. Fournier, Denis Vivien, Sara Martinez de Lizarrondo)....Pages 315-327
Front Matter ....Pages 329-329
 Magnetic Resonance Spectroscopy Studies of Mouse Models of Cancer  (Menglin Cheng, Kristine Glunde)....Pages 331-345
 MRI in the Study of Animal Models of Neurodegenerative Diseases  (Nyoman D. Kurniawan)....Pages 347-375
 MRI in the Study of Animal Models of Stroke  (Pedro Ramos-Cabrer, Daniel Padro)....Pages 377-392
Front Matter ....Pages 393-393
 Assessment of Blood Brain Barrier Leakage with Gadolinium-Enhanced MRI  (Min-Chi Ku, Sonia Waiczies, Thoralf Niendorf, Andreas Pohlmann)....Pages 395-408
 In Vivo Pharmacokinetics of Magnetic Nanoparticles  (Carlos Caro, M. Carmen Muñoz-Hernández, Manuel Pernia Leal, María Luisa García-Martín)....Pages 409-419
Front Matter ....Pages 421-421
 Anesthesia and Monitoring of Animals During MRI Studies  (Jordi L. Tremoleda, Sven Macholl, Jane K. Sosabowski)....Pages 423-439
 Advanced Contrast Agents for Multimodal Biomedical Imaging Based on Nanotechnology  (Daniel Calle, Paloma Ballesteros, Sebastián Cerdán)....Pages 441-457
Back Matter ....Pages 459-464