Practical Transfusion Medicine

Content: List of Contributors ix Preface xv 1 Introduction: Two Centuries of Progress in Transfusion Medicine 1Walter H. (Sunny) Dzik and Michael F. Murphy Part I Basic Principles of Immunohaematology 11 2 Essential Immunology for Transfusion Medicine 11Jaap Jan Zwaginga and S. Marieke van Ham 3 Human Blood Group Systems 20Geoff Daniels 4 Human Leucocyte Antigens 29Cristina V. Navarrete and Colin J. Brown 5 Platelet and Neutrophil Antigens 43Brian R. Curtis 6 Pretransfusion Testing and the Selection of Red Cell Products for Transfusion 58Mark H. Yazer and Meghan Delaney Part II Complications of Transfusions 69 7 Investigation of Acute Transfusion Reactions 69Kathryn E. Webert and Nancy M. Heddle 8 Haemolytic Transfusion Reactions 81Edwin J. Massey, Robertson D. Davenport and Richard M. Kaufman 9 Febrile and Allergic Transfusion Reactions 97Mark K. Fung and Nancy M. Heddle 10 Lung Injury and Pulmonary Oedema After Transfusion 108Steven H. Kleinman and Daryl J. Kor 11 Purported Adverse Effects of    Old Blood    118Lirong Qu and Darrell J. Triulzi 12 Transfusion  ]Induced Immunomodulation 125Amy E. Schmidt, Majed A. Refaai, Joanna M. Heal and Neil Blumberg 13 Transfusion  ]Associated Graft  ]Versus  ]Host Disease and Microchimerism 136Beth H. Shaz, Richard O. Francis and Christopher D. Hillyer 14 Posttransfusion Purpura 147Michael F. Murphy 15 Transfusion  ]Transmitted Infections 153Roger Y. Dodd and Susan L. Stramer 16 Bacterial Contamination 168Sandra Ramirez  ]Arcos and Mindy Goldman 17 Emerging Infections and Transfusion Safety 176Roger Y. Dodd Part III Practice in Blood Centres and Hospitals 184 18 Regulatory Aspects of Blood Transfusion 184William G. Murphy, Louis M. Katz and Peter Flanagan 19 The Role of Haemovigilance in Transfusion Safety 193Katharine A. Downes and Barbee I. Whitaker 20 Donors and Blood Collection 203Marc Germain, Ellen McSweeney and William G. Murphy 21 Blood Donation Testing and the Safety of the Blood Supply 215Mindy Goldman 22 Production and Storage of Blood Components 222Marissa Li, Rebecca Cardigan, Stephen Thomas and Ralph Vassallo 23 Blood Transfusion in Hospitals 233Erica M. Wood, Mark H. Yazer and Michael F. Murphy 24 Blood Transfusion in a Global Context 254David J. Roberts, Alan D. Kitchen, Stephen P. Field, Imelda Bates, Jean Pierre Allain and Meghan Delaney Part IV Clinical Transfusion Practice 264 25 Inherited and Acquired Coagulation Disorders 264Irina Chibisov and Franklin Bontempo 26 Massive Blood Loss 279John R. Hess 27 Blood Management in Acute Haemorrhage and Critical Care 287Gavin J. Murphy, Nicola Curry, Nishith N. Patel and Timothy S. Walsh 28 Point  ]of  ]Care Testing in Transfusion Medicine 302Matthew D. Neal and Louis H. Alarcon 29 Haematological Disease 312Lise J. Estcourt, Simon J. Stanworth and Michael F. Murphy 30 Blood Transfusion in the Management of Patients with Haemoglobinopathies 330Enrico M. Novelli 31 Heparin  ]Induced Thrombocytopenia 341Andreas Greinacher and Theodore E. Warkentin 32 Immunodeficiency and Immunoglobulin Therapy 357Siraj A. Misbah 33 Transfusing Neonates and Infants 371Ronald G. Strauss Part V Patient Blood Management 383 34 Development of a Patient Blood Management Programme 383Jonathan H. Waters 35 Perioperative Patient Blood Management 393Martin Rooms, Ravishankar Rao Baikady and Toby Richards 36 Restrictive Transfusion Practice and How to Implement It 405Lawrence Tim Goodnough and Neil Shah 37 Using Data to Support Patient Blood Management 416Steven M. Frank and Jack O. Wasey Part VI Cellular and Tissue Therapy and Organ Transplantation 429 38 Regulation and Accreditation in Cellular Therapy 429Zbigniew (Ziggy) M. Szczepiorkowski and Daniel Hollyman 39 Stem Cell Collection and Therapeutic Apheresis 442Khaled El  ]Ghariani and Zbigniew (Ziggy) M. Szczepiorkowski 40 Haemopoietic Stem Cell Processing and Storage 455Hira Mian, Ronan Foley and Pamela O   Hoski 41 Haematopoietic Stem Cell Transplantation 466Robert D. Danby, Rachel Protheroe and David J. Roberts 42 Cord Blood Transplantation 477Rachael Hough and Robert D. Danby 43 Recent Advances in Clinical Cellular Immunotherapy 490Mark W. Lowdell and Emma Morris 44 Tissue Banking 500Akila Chandrasekar, Paul Rooney and John N. Kearney Part VII Development of the Evidence Base for Transfusion 508 45 Observational and Interventional Trials in Transfusion Medicine 508Alan T. Tinmouth, Dean Fergusson and Paul C. Hebert 46 Getting the Most Out of the Evidence for Transfusion Medicine 520Simon J. Stanworth, Susan J. Brunskill, Carolyn Doree and Sally Hopewell 47 A Primer on Biostatistics 533Andrew W. Shih and Nancy M. Heddle 48 A Primer on Health Economics 549Seema Kacker and Aaron A. R. Tobian 49 Scanning the Future of Transfusion Medicine 560Jay E. Menitove, Paul M. Ness and Edward L. Snyder Index 572