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دانلود کتاب Practical Soft Tissue Pathology: A Diagnostic Approach: A Volume in the Pattern Recognition Series
دانلود کتاب آسیب شناسی عملی بافت نرم: یک رویکرد تشخیصی: یک جلد در سری تشخیص الگو
مشخصات کتاب
Practical Soft Tissue Pathology: A Diagnostic Approach: A Volume in the Pattern Recognition Series
ویرایش: 2
نویسندگان: Jason L. Hornick
سری:
ISBN (شابک) : 0323497144, 9780323497145
ناشر: Elsevier
سال نشر: 2018
تعداد صفحات: 605
زبان: English
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود)
حجم فایل: 101 مگابایت
قیمت کتاب (تومان) : 43,000
در صورت تبدیل فایل کتاب Practical Soft Tissue Pathology: A Diagnostic Approach: A Volume in the Pattern Recognition Series به فرمت های PDF، EPUB، AZW3، MOBI و یا DJVU می توانید به پشتیبان اطلاع دهید تا فایل مورد نظر را تبدیل نمایند.
توجه داشته باشید کتاب آسیب شناسی عملی بافت نرم: یک رویکرد تشخیصی: یک جلد در سری تشخیص الگو نسخه زبان اصلی می باشد و کتاب ترجمه شده به فارسی نمی باشد. وبسایت اینترنشنال لایبرری ارائه دهنده کتاب های زبان اصلی می باشد و هیچ گونه کتاب ترجمه شده یا نوشته شده به فارسی را ارائه نمی دهد.
توضیحاتی در مورد کتاب آسیب شناسی عملی بافت نرم: یک رویکرد تشخیصی: یک جلد در سری تشخیص الگو
بخشی از مجموعه تشخیص الگوی عمیق و کاربردی، آسیب شناسی بافت
نرم جراحی عملی، ویرایش دوم، به شما کمک می کند با استفاده
از یک رویکرد مبتنی بر الگوی اثبات شده به تشخیص دقیق برسید .
تشخیص دهندگان پیشرو شما را از طریق رایج ترین الگوهای دیده شده
در آسیب شناسی بافت نرم، استفاده از ایمونوهیستوشیمی مناسب و تست
های مولکولی، اجتناب از دام ها و انجام بهترین تشخیص راهنمایی می
کنند. تصاویر با کیفیت بالا الگوهای مورفولوژیکی کلیدی را
برای طیف کاملی از انواع شایع و نادر تومور به تصویر می‌کشد و یک
شاخص بصری در ابتدای کتاب شما را به محل دقیق آن راهنمایی
می‌کند. راهنمایی تشخیصی عمیق.
یک سازمان فصل منسجم بر اساس الگوی بافت شناسی تومورهای
بافت نرم را به روشی که در تمرین روزانه به آنها نزدیک می‌شوید در
نظر می‌گیرد و به شما کمک می‌کند به یک نتیجه برسید. تشخیص سریع و
دقیق.
یک طراحی کاربرپسند الگوهای کدهای رنگی برای موجودیت‌های
خاص و نکات کلیدی در جداول و جعبه‌های متن خلاصه می‌شوند،
بنابراین می‌توانید به سرعت و به راحتی آنچه را که هستید پیدا
کنید به دنبال.
به‌روزرسانی‌های جامع محتوا شما را در خط مقدم یافته‌های
اخیر در مورد همه بیماری‌های اصلی نئوپلاستیک و غیرنئوپلاستیک
بافت‌های نرم نگه می‌دارد.
فراخوان‌های الگوی بهبودیافته اکنون مستقیماً در این فصل پیوند
داده شده‌اند و الگوها را برای درک کارآمدتر و کامل‌تر تقویت
می‌کنند.
نسخه کتاب الکترونیکی Expert ConsultT همراه با خرید. این
تجربه کتاب الکترونیکی پیشرفته به شما امکان می‌دهد تمام
متن، شکل‌ها و مراجع کتاب را در دستگاه‌های مختلف جستجو کنید.
توضیحاتی درمورد کتاب به خارجی
Part of the in-depth and practical Pattern Recognition series,
Practical Surgical Soft Tissue Pathology, 2nd Edition,
helps you arrive at an accurate diagnosis by using a proven
pattern-based approach. Leading diagnosticians guide you
through the most common patterns seen in soft tissue pathology,
applying appropriate immunohistochemistry and molecular
testing, avoiding pitfalls, and making the best diagnosis.
High-quality illustrations capture key morphologic
patterns for a full range of common and rare tumor types, and a
visual index at the beginning of the book directs you to
the exact location of in-depth diagnostic guidance.
A consistent chapter organization by histologic pattern
considers soft tissue tumors the way you approach them in daily
practice, helping you arrive at a quick and accurate
diagnosis.
A user-friendly design color-codes patterns to specific
entities, and key points are summarized in tables and text
boxes, so you can quickly and easily find what you are looking
for.
Sweeping content updates keep you at the forefront of
recent findings regarding all major neoplastic and
non-neoplastic diseases of the soft tissues.
Improved pattern call-outs are now linked directly within the
chapter, reinforcing the patterns for more efficient and
complete understanding.
Expert ConsultT eBook version included with purchase. This
enhanced eBook experience allows you to search all of
the text, figures, and references from the book on a variety of
devices.
فهرست مطالب
Cover Pattern Recognition Series Practical Soft Tissue Pathology: A Diagnostic Approach Copyright Page Dedication Contributors Series Preface Preface to the First Edition Preface Acknowledgment Pattern-Based Approach to Diagnosis Pattern 1 Spindle Cell Pattern 2 Epithelioid Pattern 3 Pleomorphic Pattern 4 Round Cell Pattern 5 Biphasic or Mixed Pattern 6 Myxoid 1 Introduction: Tumor Classification and Immunohistochemistry Tumor Classification Immunohistochemistry Intermediate Filament Proteins Other Myogenic Markers Endothelial Markers Schwannian Markers Other Diagnostic Markers Protein Correlates of Genetic Alterations Novel Markers Discovered by Gene Expression Profiling References 2 Biologic Potential, Grading, Staging, and Reporting of Sarcomas Biologic Potential Sarcoma Grading Sarcoma Staging Surgical Margins References 3 Spindle Cell Tumors of Adults General Concepts Approach to the Diagnosis of Spindle Cell Tumors of Soft Tissue Frequency Clinical Context Histologic Parameters Ancillary Techniques Nonmesenchymal Neoplasms With Spindle Cell Cytomorphology Spindle Cell Carcinoma Spindle Cell Melanoma and Variants Malignant Mesothelioma Nodular Fasciitis and Similar Pseudosarcomatous Myofibroblastic Lesions Nodular Fasciitis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pseudosarcomatous Myofibroblastic Proliferation Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Mycobacterial Spindle Cell Pseudotumor Myofibroma and Myopericytoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Phosphaturic Mesenchymal Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myofibroblastoma and Variants Mammary-Type Myofibroblastoma Intranodal Palisaded Myofibroblastoma Fibroma Fibroma of Tendon Sheath Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Desmoplastic Fibroblastoma (Collagenous Fibroma) Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Nuchal-Type Fibroma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Elastofibroma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Calcifying Fibrous Tumor Angiofibroma of Soft Tissue Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Fibrous Histiocytoma and Variants Deep Fibrous Histiocytoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Solitary Fibrous Tumor and Variants Solitary Fibrous Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Giant Cell–Rich Solitary Fibrous Tumor (Giant Cell Angiofibroma) Fat-Forming Solitary Fibrous Tumor (Lipomatous Hemangiopericytoma) Meningeal Solitary Fibrous Tumor Fibromatoses Superficial Fibromatoses Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Deep Fibromatosis (Desmoid Fibromatosis) Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Spindle Cell Lipoma Atypical Spindle Cell Lipomatous Tumor Schwannoma and Variants Conventional Schwannoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Cellular Schwannoma Plexiform Schwannoma Epithelioid Schwannoma Melanotic Schwannoma Microcystic/Reticular Schwannoma Schwannomatosis and Genetic Predisposition to Particular Types of Schwannoma Neurofibroma Localized Neurofibroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Diffuse Neurofibroma Plexiform Neurofibroma Neurofibroma in Neurofibromatosis Malignant Transformation in Neurofibroma Perineurioma Soft Tissue Perineurioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Intraneural Perineurioma Sclerosing Perineurioma Ganglioneuroma Benign Smooth Muscle Tumors Leiomyoma of Deep Soft Tissue and Related Lesions (Myolipoma/Lipoleiomyoma) Clinical Features Pathologic Features Criteria for Malignancy Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Angioleiomyoma Disseminated Peritoneal Leiomyomatosis, Intravenous Leiomyomatosis, and Benign Metastasizing Leiomyoma Leiomyosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Epstein-Barr Virus–Associated Smooth Muscle Neoplasm Lymphangiomyoma and Lymphangiomyomatosis Angiomatoid Fibrous Histiocytoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Synovial Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Malignant Peripheral Nerve Sheath Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Biphenotypic Sinonasal Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Sarcomas With Fibroblastic Differentiation Adult-Type Fibrosarcoma Low-Grade Fibromyxoid Sarcoma and Variants Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Low-Grade Myofibroblastic Sarcoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Spindle Cell Rhabdomyosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Clear Cell Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pseudomyogenic Hemangioendothelioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Unclassified Spindle Cell Sarcomas References 4 Pediatric Spindle Cell Tumors Fibroblastic-Myofibroblastic Tumors Benign Tumors That Mimic Sarcomas Nodular Fasciitis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Cranial Fasciitis Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Fibromas Gardner Fibroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Cardiac Fibroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Fibromatoses Infantile Myofibroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Desmoid-Type Fibromatosis in Childhood Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Fibromatosis Colli Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Infantile Digital Fibroma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Fibrous Hamartoma of Infancy Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Calcifying Aponeurotic Fibroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Lipofibromatosis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Juvenile Nasopharyngeal Angiofibroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Hyaline Fibromatosis Syndrome Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Intermediate/Rarely Metastasizing Fibroblastic Tumors of Childhood Inflammatory Myofibroblastic Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Infantile Fibrosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Primitive Myxoid Mesenchymal Tumor of Infancy Sarcomas Low-Grade Fibromyxoid Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Low-Grade Myofibrosarcoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Infantile Rhabdomyofibrosarcoma Other Spindle Cell Tumors of Childhood and Adolescence Fetal Rhabdomyoma Spindle Cell Rhabdomyosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Undifferentiated Sarcoma in Childhood References 5 Tumors With Myxoid Stroma Ganglion Cyst Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Intramuscular/Cellular Myxoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Juxtaarticular Myxoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Dermal Nerve Sheath Myxoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Superficial Acral Fibromyxoma (Digital Fibromyxoma) Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Superficial Angiomyxoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Deep Angiomyxoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Ossifying Fibromyxoid Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myoepithelioma and Myoepithelial Carcinoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxofibrosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxoid Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Extraskeletal Myxoid Chondrosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Low-Grade Fibromyxoid Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxoinflammatory Fibroblastic Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxoid Nerve Sheath Tumors Myxoid Neurofibroma Reticular and Myxoid Soft Tissue Perineurioma Microcystic/Reticular (Myxoid) Schwannoma Myxoid Malignant Peripheral Nerve Sheath Tumor Other Tumors With Myxoid Stroma Myxoid Nodular Fasciitis Myxoid Dermatofibrosarcoma Protuberans Myxoid Solitary Fibrous Tumor Myxoid Synovial Sarcoma References 6 Epithelioid and Epithelial-Like Tumors Approach to the Diagnosis of Epithelioid Tumors of Soft Tissue Clinical Presentation Microscopic Examination Immunohistochemistry Cytogenetics Epithelioid Hemangioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Glomus Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myoepithelioma/Mixed Tumor/Myoepithelial Carcinoma of Soft Tissue Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment PEComa of Soft Tissue Clinical Features Renal and Extrarenal Angiomyolipoma PEComa Pathologic Features Renal and Extrarenal Angiomyolipoma PEComa Immunohistochemistry Molecular Genetics Differential Diagnosis Renal and Extrarenal Epithelioid Angiomyolipoma PEComa Prognosis and Treatment Renal and Extrarenal Epithelioid Angiomyolipoma PEComa Adult-Type Rhabdomyoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Epithelioid Schwannoma Granular Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Sclerosing Perineurioma Extracranial Meningioma Ossifying Fibromyxoid Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Ependymoma of Soft Tissue Alveolar Soft Part Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Epithelioid Hemangioendothelioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Epithelioid Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment SMARCA4-Deficient Thoracic Sarcoma Extrarenal Malignant Rhabdoid Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Sclerosing Epithelioid Fibrosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Epithelioid and Epithelial-Like Variants of Other Sarcomas Epithelioid Angiosarcoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Epithelioid Malignant Peripheral Nerve Sheath Tumor Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Epithelioid Gastrointestinal Stromal Tumor Epithelioid Myxofibrosarcoma Pleomorphic Liposarcoma, Epithelioid Variant Synovial Sarcoma, Epithelial/Glandular Variant Glandular Malignant Peripheral Nerve Sheath Tumor Other Epithelioid Variants of Specific Sarcomas References 7 Pleomorphic Sarcomas Atypical Fibroxanthoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Undifferentiated Pleomorphic Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pleomorphic Hyalinizing Angiectatic Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxoinflammatory Fibroblastic Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxofibrosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pleomorphic Myogenic Sarcomas Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pleomorphic Lipogenic Sarcomas Pleomorphic Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Dedifferentiated Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Extraskeletal Osteosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Malignant Mesenchymoma Algorithmic Approach When Confronted With a Pleomorphic Sarcomatoid Neoplasm Grading of Pleomorphic Sarcomas The Role of Imaging Studies in the Diagnosis of Pleomorphic Sarcomas References 8 Round Cell Tumors The Role of Immunohistochemistry and Molecular Genetics How Should Small Round Cell Sarcoma Samples Be Handled? Should Molecular Techniques to Detect Translocations Always Be Performed? Ewing Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Alveolar Rhabdomyosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Embryonal Rhabdomyosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment “Round Cell” Liposarcoma Desmoplastic Small Round Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Poorly Differentiated Synovial Sarcoma, Round Cell Variant Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Undifferentiated Round Cell Sarcomas CIC-Rearranged Sarcomas BCOR-Rearranged Sarcomas References 9 Biphasic Tumors and Tumors With Mixed Patterns Biphasic Synovial Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Mixed Tumor/Myoepithelioma/ Myoepithelial Carcinoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Malignant Peripheral Nerve Sheath Tumor With Divergent (Heterologous) Differentiation (Including Glandular Type) Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Ectopic Hamartomatous Thymoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Gastrointestinal Stromal Tumor, Mixed Type Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Dedifferentiated Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Melanotic Neuroectodermal Tumor of Infancy Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Nonmesenchymal Tumors With Biphasic and Mixed Patterns Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis References 10 Soft Tissue Tumors With Prominent Inflammatory Cells Inflammatory Myofibroblastic Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Inflammatory Leiomyosarcoma Histiocytic and Dendritic Cell Tumors Follicular Dendritic Cell Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Fibroblastic Reticular Cell Sarcoma Interdigitating Dendritic Cell Sarcoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Langerhans Cell Histiocytosis and Langerhans Cell Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Indeterminate Cell Histiocytosis Extranodal Rosai-Dorfman Disease Histiocytic Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Angiomatoid Fibrous Histiocytoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxoinflammatory Fibroblastic Sarcoma Well-Differentiated Inflammatory Liposarcoma Inflammatory Malignant Fibrous Histiocytoma Mass-Forming Idiopathic Fibroinflammatory Disorders Sclerosing Mesenteritis Idiopathic Retroperitoneal Fibrosis Immunoglobulin G4–Related Disease References 11 Giant Cell–Rich Tumors Tenosynovial Giant Cell Tumors Giant Cell Tumor of Tendon Sheath (Localized-Type Tenosynovial Giant Cell Tumor) Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Diffuse-Type (Tenosynovial) Giant Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Malignant Diffuse-Type (Tenosynovial) Giant Cell Tumor Molecular Genetics Tumors of Superficial Soft Tissues Plexiform Fibrohistiocytic Tumor Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Giant Cell Tumor of Soft Tissue Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Giant Cell–Rich Sarcomas and Histologic Mimics Clinical Features Pathologic Features Giant Cell–Rich Extraskeletal Osteosarcoma. Leiomyosarcoma With Prominent Osteoclast-Like Giant Cells. Giant Cell–Rich Anaplastic Carcinomas. Large Cell Lymphomas. References 12 Adipocytic Tumors Lipoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Lipofibromatosis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Lipomatosis of Nerve Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Angiolipoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Spindle Cell/Pleomorphic Lipoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Hemosiderotic Fibrolipomatous Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Lipoblastoma/Lipoblastomatosis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Hibernoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myolipoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Chondroid Lipoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Liposarcoma Atypical Lipomatous Tumor/ Well-Differentiated Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Dedifferentiated Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxoid Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pleomorphic Liposarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Acknowledgment References 13 Vascular Tumors Immunohistochemistry Classification of Vascular Tumors Vasoformative Pattern Papillary Endothelial Hyperplasia (Masson Tumor) Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Bacillary Angiomatosis Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Reactive Angioendotheliomatosis Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Glomeruloid Hemangioma Clinical Features Pathologic Features Differential Diagnosis Acroangiodermatitis (Pseudo-Kaposi Sarcoma) Clinical Features Pathologic Features Differential Diagnosis Vascular Ectasias Vascular Malformations Cavernous Hemangioma and Venous Hemangioma (Venous Malformation) Clinical Features Pathologic Features Differential Diagnosis Sinusoidal Hemangioma Clinical Features Pathologic Features Differential Diagnosis Arteriovenous Hemangioma and Arteriovenous Malformation Clinical Features Pathologic Features Lymphangioma/Lymphatic Malformation Clinical Features Pathologic Features Differential Diagnosis Acquired Progressive Lymphangioma (Benign Lymphangioendothelioma) Clinical Features Pathologic Features Differential Diagnosis Intramuscular Angioma Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Synovial Hemangioma Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Angiomatosis and Lymphangiomatosis Clinical Features Pathologic Features Prognosis and Treatment Capillary Hemangioma Juvenile Capillary Hemangioma (Infantile Hemangioma) Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Congenital Nonprogressive Hemangioma Clinical Features Pathologic Features Immunohistochemistry Lobular Capillary Hemangioma (Pyogenic Granuloma) Clinical Features Pathologic Features Differential Diagnosis Cherry Angioma Clinical Features Pathologic Features Acquired Elastotic Hemangioma Clinical Features Pathologic Features Verrucous Hemangioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Tufted Angioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Symplastic Hemangioma Clinical Features Pathologic Features Microvenular Hemangioma Clinical Features Pathologic Features Differential Diagnosis Hobnail Hemangioma (“Targetoid Hemosiderotic Hemangioma”) Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Papillary Intralymphatic Angioendothelioma (Dabska Tumor) Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Retiform Hemangioendothelioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Composite Hemangioendothelioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Angiosarcoma Clinical Features Cutaneous Angiosarcoma. Soft Tissue Angiosarcoma. Mammary Angiosarcoma. Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Postradiation Atypical Vascular Lesion Clinical Features Pathologic Features Differential Diagnosis Prognosis and Treatment Epithelioid Lesions Epithelioid Hemangioma (Including Angiolymphoid Hyperplasia With Eosinophilia) Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Epithelioid Angiomatous Nodule Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Epithelioid Hemangioendothelioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Epithelioid Angiosarcoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Spindle Cell Lesions Spindle Cell Hemangioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Kaposiform Hemangioendothelioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Kaposi Sarcoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Angiosarcoma (Spindle Cell) Pathologic Features Differential Diagnosis References 14 Cartilaginous and Osseous Soft Tissue Lesions Myositis Ossificans and Heterotopic Ossification Clinical Features Pathologic Features Immunohistochemistry and Molecular Genetics Differential Diagnosis Prognosis and Treatment Fibro-Osseous Pseudotumor of the Digits Clinical Features Pathologic Features Immunohistochemistry and Molecular Genetics Differential Diagnosis Prognosis and Treatment Fibrodysplasia Ossificans Progressiva Clinical Features Pathologic Features Molecular Genetics Differential Diagnosis Prognosis and Treatment Tumoral Calcinosis and Tumoral Calcinosis–Like Lesions Clinical Features Pathologic Features Molecular Genetics Differential Diagnosis Prognosis and Treatment Soft Tissue Chondroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Synovial Chondromatosis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Soft Tissue Aneurysmal Bone Cyst Clinical Features Pathologic Features Molecular Genetics Differential Diagnosis Prognosis and Treatment Extraskeletal Myxoid Chondrosarcoma Extraskeletal Mesenchymal Chondrosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Extraskeletal Osteosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Neoplasms Showing Heterologous Osteocartilaginous Differentiation References 15 Cutaneous Mesenchymal Tumors Spindle Cell Tumors Benign Fibrous Histiocytoma (Dermatofibroma) and Variants Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Cellular Benign Fibrous Histiocytoma Aneurysmal Benign Fibrous Histiocytoma Atypical (Pseudosarcomatous) Fibrous Histiocytoma Dermatomyofibroma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Pilar Leiomyoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Atypical Intradermal Smooth Muscle Neoplasm Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Storiform Collagenoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Solitary Circumscribed Neuroma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Dermatofibrosarcoma Protuberans Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Giant Cell Fibroblastoma Perineurioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Hybrid Schwannoma/Perineurioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Dendritic Cell Neurofibroma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Pseudomyogenic Hemangioendothelioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Myxoid Tumors Superficial Acral Fibromyxoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Superficial Angiomyxoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Digital Mucous Cyst (Cutaneous Myxoid Cyst) Cutaneous Focal Mucinosis Dermal Nerve Sheath Myxoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Epithelioid Tumors Granular Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Nonneural Granular Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Epithelioid Fibrous Histiocytoma Cutaneous Myoepithelioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Cellular Neurothekeoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Perivascular Epithelioid Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Distinctive Dermal Clear Cell Mesenchymal Neoplasm Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Epithelioid Schwannoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Sclerosing Perineurioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Cutaneous Meningioma and Ectopic Meningothelial Hamartoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Nasal Glioma (Nasal Glial Heterotopia) Juvenile Xanthogranuloma and Related Disorders Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Reticulohistiocytoma Multicentric Reticulohistiocytosis Cutaneous Rosai-Dorfman Disease Epithelioid Sarcoma Pleomorphic Tumors Atypical Fibroxanthoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pleomorphic Dermal Sarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Pleomorphic Fibroma Adipocytic Tumors Dermal Lipoma and Nevus Lipomatosus Superficialis Clinical Features Pathologic Features Prognosis and Treatment Dermal Spindle Cell Lipoma and Pleomorphic Lipoma References 16 Mesenchymal Tumors of the Gastrointestinal Tract Gastrointestinal Stromal Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Leiomyoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Leiomyosarcoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Schwannoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Gastrointestinal Clear Cell Sarcoma-like Tumor Clinical Features Pathologic Features Immunohistochemistry and Ultrastructure Molecular Genetics Differential Diagnosis Prognosis and Treatment Inflammatory Myofibroblastic Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Desmoid Fibromatosis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Inflammatory Fibroid Polyp Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Plexiform Fibromyxoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Perivascular Epithelioid Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Glomus Tumor Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Polypoid Ganglioneuroma and Ganglioneuromatosis Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Granular Cell Tumor Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Mucosal Perineurioma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Mucosal Schwann Cell Hamartoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment References 17 Lower Genital Soft Tissue Tumors General Approach to Soft Tissue Lesions of the Lower Genital Tract Deep (Aggressive) Angiomyxoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Fibroepithelial Stromal Polyp Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Angiomyofibroblastoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Cellular Angiofibroma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Prepubertal Vulval Fibroma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Mammary-Type Myofibroblastoma Clinical Features Pathologic Features Immunohistochemistry Molecular Genetics Differential Diagnosis Prognosis and Treatment Spindle Cell Epithelioma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Genital Rhabdomyoma Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment Genital Smooth Muscle Tumors Clinical Features Pathologic Features Immunohistochemistry Differential Diagnosis Prognosis and Treatment References 18 Applications of Molecular Testing to Differential Diagnosis Keywords Genetic Classification of Sarcomas Approaches to Molecular Diagnostics The Paradigm of Ewing Sarcoma Techniques Chromosomal Karyotype Fluorescence In Situ Hybridization Reverse Transcription Polymerase Chain Reaction Next-Generation Sequencing Molecular Assays. Molecular Features of Particular Entities Soft Tissue Sarcomas With Complex Cytogenetic Features Soft Tissue Sarcomas With Simple Cytogenetic Features Alveolar Soft Part Sarcoma Angiomatoid Fibrous Histiocytoma Angiosarcoma Benign Fibrous Histiocytoma (Dermatofibroma) Biphenotypic Sinonasal Sarcoma Clear Cell Sarcoma Dermatofibrosarcoma Protuberans Desmoid-Type Fibromatosis Desmoplastic Small Round Cell Tumor Endometrial Stromal Sarcoma Epithelioid Hemangioendothelioma Ewing Sarcoma Ewing-Like Tumors With Alternative Fusion Transcripts Extraskeletal Myxoid Chondrosarcoma Glomus Tumors Gastrointestinal Stromal Tumor Infantile Fibrosarcoma Inflammatory Myofibroblastic Tumor Leiomyoma Lipoma Variants (Benign Adipocytic Tumors) Conventional Lipoma. Other Lipoma Variants. Liposarcoma Myxoid Liposarcoma. Well-Differentiated and Dedifferentiated Liposarcoma. Lipofibromatosis-Like Neural Tumors Low-Grade Fibromyxoid Sarcoma Mesenchymal Chondrosarcoma Myoepithelial Tumors of Soft Tissue Myxoinflammatory Fibroblastic Sarcoma and Hemosiderotic Fibrolipomatous Tumor Myxomas Neurofibroma Nodular Fasciitis Ossifying Fibromyxoid Tumor Pericytoma With t(7;12) Pseudomyogenic Hemangioendothelioma Rhabdomyosarcoma Sclerosing Epithelioid Fibrosarcoma Schwannoma Synovial Sarcoma Solitary Fibrous Tumor Tenosynovial Giant Cell Tumor Practical Applications of Molecular Diagnostic Testing Desmoplastic Small Round Cell Tumor Versus Ewing Sarcoma Clear Cell Sarcoma Versus Metastatic Melanoma Well-Differentiated Liposarcoma With Myxoid Stroma Versus Myxoid Liposarcoma Solid Alveolar Rhabdomyosarcoma Versus Embryonal Rhabdomyosarcoma Extraskeletal Myxoid Chondrosarcoma Versus Soft Tissue Myoepithelioma/Myoepithelial Carcinoma Small Cell (Poorly Differentiated) Synovial Sarcoma Versus Ewing Sarcoma Gastrointestinal Stromal Tumor With Unusual Features Significance of Detecting an EWSR1 Gene Rearrangement by Fluorescence In Situ Hybridization Conclusions References Index A B C D E F G H I J K L M N O P R S T U V W X
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