Practical clinical microbiology and infectious diseases: a hands-on guide

Cover......Page 1
Half Title......Page 2
Title Page......Page 4
Copyright Page......Page 5
Contents......Page 6
Preface......Page 16
Acknowledgements......Page 18
Editor......Page 20
Contributors......Page 22
Section I: Principles of Infection Management......Page 24
 Chapter 1.1: Pillars of Infection Management......Page 26
 Chapter 1.2: Diagnostic Stewardship......Page 29
 Chapter 1.3: Antimicrobial Stewardship......Page 35
 Chapter 1.4: Infection Prevention and Control......Page 41
Section II: Diagnosis of Infections......Page 48
 Chapter 2.1: Commensal Flora......Page 50
 Chapter 2.2: Diagnosing Bacterial Infections......Page 55
 Chapter 2.3: Diagnosing Viral Infections......Page 59
 Chapter 2.4: Diagnosing Invasive Fungal Infections......Page 65
 Chapter 2.5: Diagnosing Parasitic Infections......Page 71
 Chapter 2.6: Laboratory Detection of ß-Lactam Resistance in .Enterobacterales......Page 76
 Chapter 2.7: Understanding the Antibiogram......Page 83
 Chapter 2.8: Understanding Microbiology Culture Results......Page 86
 Chapter 2.9: Understanding Serology......Page 93
 Chapter 2.10: Understanding Molecular Diagnosis......Page 98
Section III: Treatment of Infections......Page 102
 Chapter 3.1: Basic Principles of Antibiotic Treatment......Page 104
 Chapter 3.2: Basic Principles of Antifungal Treatment......Page 107
 Chapter 3.3: ß-Lactam Allergy......Page 112
 Chapter 3.4: Antimicrobials in Pregnant Women......Page 115
 Chapter 3.5: Antimicrobial Agents and Liver Injury......Page 118
 Chapter 3.6: Antimicrobial Agents and Neurotoxicity......Page 122
 Chapter 3.7: Antimicrobial Agents and Drug Interactions......Page 127
 Chapter 3.8: Pharmacokinetic and Pharmacodynamic Considerations......Page 131
 Chapter 3.9: Source Control......Page 136
 Chapter 3.10: Antibiotic Treatment Failure......Page 140
Section IV: Special Problems......Page 144
 Chapter 4.1: Acute Streptococcal Pharyngitis......Page 146
 Chapter 4.2: Animal Bites......Page 152
 Chapter 4.3: Asymptomatic Bacteriuria......Page 157
 Chapter 4.4: Atypical Pneumonia......Page 160
 Chapter 4.5: Bacterial Skin and Soft Tissue Infections......Page 163
 Chapter 4.6: Bloodstream Infections......Page 167
 Chapter 4.7: Bordetella pertussis......Page 172
 Chapter 4.8: Breast Abscess......Page 177
 Chapter 4.9: Bronchiectasis......Page 180
 Chapter 4.10: Bronchitis......Page 182
 Chapter 4.11: Brucellosis......Page 184
 Chapter 4.12: Candiduria......Page 188
 Chapter 4.13: Cardiac Implantable Device Infections......Page 190
 Chapter 4.14: Chlamydia trachomatis......Page 194
 Chapter 4.15: Cholangitis......Page 197
 Chapter 4.16: Deep Neck Space Infection......Page 200
 Chapter 4.17: Empyema......Page 202
 Chapter 4.18: Encephalitis......Page 204
 Chapter 4.19: Endocarditis......Page 208
 Chapter 4.20: Neisseria gonorrhoeae......Page 212
 Chapter 4.21: Hepatitis A......Page 215
 Chapter 4.22: Hepatitis B......Page 217
 Chapter 4.23: Hepatitis C......Page 221
 Chapter 4.24: Hepatitis E......Page 224
 Chapter 4.25: Histoplasmosis......Page 227
 Chapter 4.26: Human Immunodeficiency Virus and Opportunistic Infections......Page 230
 Chapter 4.27: Infections in Haematopoietic Stem Cell Transplants......Page 235
 Chapter 4.28: Infections in the ICU......Page 238
 Chapter 4.29: Infectious Diarrhoea......Page 243
 Chapter 4.30: Influenza......Page 248
 Chapter 4.31: Intra-Abdominal Infections......Page 252
 Chapter 4.32: Invasive Candidiasis......Page 257
 Chapter 4.33: Invasive Group A Streptococcal Infections......Page 263
 Chapter 4.34: Invasive Pulmonary Aspergillosis......Page 266
 Chapter 4.35: Keratitis......Page 271
 Chapter 4.36: Lung Abscess......Page 274
 Chapter 4.37: Measles......Page 276
 Chapter 4.38: Meningitis......Page 280
 Chapter 4.39: Near-Drowning-Associated Pneumonia......Page 284
 Chapter 4.40: Neutropaenic Sepsis......Page 287
 Chapter 4.41: Non-Resolving Pneumonia......Page 290
 Chapter 4.42: Norovirus......Page 294
 Chapter 4.43: Onychomycosis......Page 298
 Chapter 4.44: Osteomyelitis......Page 301
 Chapter 4.45: Otitis Externa......Page 304
 Chapter 4.46: Pelvic Inflammatory Disease......Page 308
 Chapter 4.47: Perianal Abscess......Page 311
 Chapter 4.48: Pneumocystis jirovecii: Pneumonia (PJP) in Patients with a Haematological Malignancy or Solid Organ Transplant......Page 314
 Chapter 4.49: Pneumonia (CAP, HAP and VAP)......Page 319
 Chapter 4.50: Post-Exposure Prophylaxis for Healthcare  Workers Exposed to Blood-Borne Viruses......Page 322
 Chapter 4.51: Post-Operative Infections......Page 327
 Chapter 4.52: Prosthetic Joint Infections......Page 333
 Chapter 4.53: Prostatitis......Page 336
 Chapter 4.54: Pyomyositis......Page 341
 Chapter 4.55: Ringworm......Page 344
 Chapter 4.56: Salmonella Carriage......Page 346
 Chapter 4.57: Septic Arthritis......Page 350
 Chapter 4.58: Septic Bursitis......Page 356
 Chapter 4.59: Splenectomy......Page 359
 Chapter 4.60: The Immunocompromised Patient......Page 362
 Chapter 4.61: Typhoid Fever......Page 366
 Chapter 4.62: Urinary Tract Infections......Page 370
 Chapter 4.63: Uveitis......Page 377
 Chapter 4.64: Varicella Zoster......Page 380
Section V: Difficult-to-Treat Organisms......Page 386
 Chapter 5.1: AmpC, Extended-Spectrum ß-Lactamase and Carbapenemase Producers......Page 388
 Chapter 5.2: Acinetobacter baumannii......Page 396
 Chapter 5.3: Achromobacter xylosoxidans......Page 399
 Chapter 5.4: Pseudomonas aeruginosa......Page 401
 Chapter 5.5: Stenotrophomonas maltophilia......Page 406
 Chapter 5.6: Staphylococcus aureus......Page 408
 Chapter 5.7: Vancomycin-Resistant Enterococci......Page 413
 Chapter 5.8: Helicobacter pylori......Page 416
 Chapter 5.9: Clostridioides difficile......Page 420
 Chapter 5.10: Actinomycosis......Page 424
 Chapter 5.11: Nocardia......Page 426
Section VI: Appendix......Page 430
 Chapter 6.1: Syndromic Approach to Infections......Page 432
 Chapter 6.2: Specimen Collection......Page 442
 Chapter 6.3: Spectrum of Activity of Antibiotics......Page 444
 Chapter 6.4: Doses of Common Antimicrobials......Page 447
 Chapter 6.5: Pathogen-Specific Infection Control Precautions......Page 455
 Chapter 6.6: Pillars of Infection Control......Page 464
 Chapter 6.7: Transmission-Based Precautions......Page 467
Index......Page 470