Post-Genomic Perspectives in Modeling and Control of Breathing

Front Matter....Pages 1-1
Different Profile in Ventilatory vs. Respiratory Sensation Responses to CO 2 with Varying Po 2 ....Pages 3-7
Amygdala and Emotional Breathing in Humans....Pages 9-14
Immediate Effects of Bilateral Carotid Body Resection on Total Respiratory Resistance and Compliance in Humans....Pages 15-21
Memories of Yoshiyuki Honda, MD, PhD....Pages 23-26
Memories of Dr. Yoshiyuki Honda....Pages 27-28
Front Matter....Pages 29-29
Chemosensory Control of the Respiratory Function....Pages 31-38
Brainstem NHE-3 Expression and Control of Breathing....Pages 39-44
Functional Connection From the Surface Chemosensitive Region to the Respiratory Neuronal Network in the Rat Medulla....Pages 45-51
Chemosensory Inputs and Neural Remodeling in Carotid Body and Brainstem Catecholaminergic Cells....Pages 53-58
Role of Fe 2+ in Oxygen Sensing in the Carotid Body....Pages 59-64
Ventilatory Responsiveness to CO 2 Above & Below Eupnea: Relative Importance of Peripheral Chemoreception....Pages 65-70
Carotid Body Tumors in Humans Caused by a Mutation in the Gene for Succinate Dehydrogenase D (SDHD)....Pages 71-76
A SIDS-Like Phenotype is Associated With Reduced Respiratory Chemoresponses in PACAP Deficient Neonatal Mice....Pages 77-83
Selective Alteration of the Ventilatory Response to Hypoxia Results from Mutation in the Myelin Proteolipid Protein Gene....Pages 85-91
Front Matter....Pages 93-93
Organization of Central Pathways Mediating the Hering-Breuer Reflex and Carotid Chemoreflex....Pages 95-100
Converging Functional and Anatomical Evidence for Novel Brainstem Respiratory Compartments in the Rat....Pages 101-105
Eupneic Respiratory Rhythm in Awake Goats is Dependent on an Intact Pre-Bötzinger Complex....Pages 107-113
BDNF Preferentially Targets Membrane Properties of Rhythmically Active Neurons in the pre-Bötzinger Complex in Neonatal Mice....Pages 115-120
Ionic Currents and Endogenous Rhythm Generation in the pre-Bötzinger Complex: Modelling and In Vitro Studies....Pages 121-126
Modulation of Inspiratory Inhibition of the Bötzinger Complex by Raphe Pallidus and Locus Coeruleus in Rabbits....Pages 127-133
Front Matter....Pages 93-93
Behavioural Control of Breathing in Mammals: Role of the Midbrain Periaqueductal Gray....Pages 135-141
Breathing at Birth: Influence of Early Developmental Events....Pages 143-148
Front Matter....Pages 149-149
A Dual-Role Played by Extracellular ATP in Frequency-Filtering of the Nucleus Tractus Solltarii Network....Pages 151-156
Role of GABA in Central Respiratory Control Studied in Mice Lacking GABA-Synthesizing Enzyme 67-kDa Isoform of Glutamic Acid Decarboxylase....Pages 157-163
Breathing Without Acetylcholinesterase....Pages 165-170
In-Silico Model of NMDA and Non-NMDA Receptor Activities Using Analog Very-Large-Scale Integrated Circuits....Pages 171-175
Respiratory Role of Ionotropic Glutamate Receptors in the Rostral Ventral Respiratory Group of the Rabbit....Pages 177-182
Serotonergic Receptors and Effects in Hypoglossal and Laryngeal Motoneurons....Pages 183-188
Modelling Respiratory Rhythmogenesis: Focus on Phase Switching Mechanisms....Pages 189-194
Front Matter....Pages 195-195
Ventilatory Instability Induced by Selective Carotid Body Inhibition in the Sleeping Dog....Pages 197-201
Stability Analysis of the Respiratory Control System During Sleep....Pages 203-209
A Physical Model of Inspiratory Flow Limitation in Awake Healthy Subjects....Pages 211-216
Antioxidants Prevent Blunting of Hypoxic Ventilatory Response by Low-Dose Halothane....Pages 217-220
Mechanism of Propofol-Induced Central Respiratory Depression in Neonatal Rats....Pages 221-226
Interaction of Arousal States with Depression of Acute Hypoxic Ventilatory Response by 0.1 MAC Halothane....Pages 227-233
Front Matter....Pages 235-235
Relationship Between Ventilatory and Circulatory Responses to Sustained Mild Hypoxia in Humans....Pages 237-241
Respiratory, Cerebrovascular and Pressor Responses to Acute Hypoxia: Dependency on Pet Co 2 ....Pages 243-249
Can Cardiogenic Oscillations Provide an Estimate of Chest Wall Mechanics?....Pages 251-257
Nonlinear Modeling of the Dynamic Effects of Arterial Pressure and Blood Gas Variations on Cerebral Blood Flow in Healthy Humans....Pages 259-265
Front Matter....Pages 267-267
Mixed Venous CO 2 and Ventilation During Exercise and CO 2 -Rebreathing in Humans....Pages 269-274
Front Matter....Pages 267-267
Effects of Pain and Audiovisual Stimulation on the Hypoxic Ventllatory Response....Pages 275-279
Effect of Progressive Hypoxia with Moderate Hypercapnia on Ventilatory vs. Respiratory Sensation Responses in Humans....Pages 281-285
Frequency Response of the Input Reaching the Respiratory Centres During Moderate Intensity Exercise....Pages 287-290
Front Matter....Pages 291-291
Effects of Resistive Loading on Breathing Variability....Pages 293-298
Effects of Intermittent Hypoxic Training and Detraining on Ventilatory Chemosensitive Adaptations in Endurance Athletes....Pages 299-304
Effects of 5 Consecutive Nocturnal Hypoxic Exposures on Respiratory Control and Hematogenesis in Humans....Pages 305-310
Memory, Reconsolidation and Extinction in Lymnaea Require the Soma of RPeD1....Pages 311-318
Front Matter....Pages 319-319
Modeling and Control of Breathing: Perspectives from Pre- to Post-Genomic Era....Pages 321-322
Post-Genomic Perspectives in Modeling and Control of Breathing....Pages 323-326