Positive-Strand RNA Viruses

Front Matter....Pages i-x
The importance of antigenic variation in vaccine design....Pages 1-8
Front Matter....Pages 9-9
The genetic and functional basis of HIV-1 resistance to nonnucleoside reverse transcriptase inhibitors....Pages 11-17
Structure-based design of symmetric inhibitors of HIV-1 protease....Pages 19-29
Age-dependent susceptibility to fatal encephalitis: alphavirus infection of neurons....Pages 31-39
Principles and background for the construction of transgenic plants displaying multiple virus resistance....Pages 41-50
The structure of an immunodominant loop on foot and mouth disease virus, serotype O1, determined under reducing conditions....Pages 51-58
Immunopathologic mechanisms of dengue hemorrhagic fever and dengue shock syndrome....Pages 59-64
Front Matter....Pages 65-65
Cardioviral poly(C) tracts and viral pathogenesis....Pages 67-77
Transgenic mice and the pathogenesis of poliomyelitis....Pages 79-86
Adaptation of positive-strand RNA viruses to plants....Pages 87-97
A molecular genetic approach to the study of Venezuelan equine encephalitis virus pathogenesis....Pages 99-109
Use of drug-resistance mutants to identify functional regions in picornavirus capsid proteins....Pages 111-119
Flock house virus: a simple model for studying persistent infection in cultured Drosophila cells....Pages 121-132
Front Matter....Pages 133-133
Protein-protein interactions and glycerophospholipids in bromovirus and nodavirus RNA replication....Pages 135-145
Characteristics of the poliovirus replication complex....Pages 147-157
Secretory pathway function, but not cytoskeletal integrity, is required in poliovirus infection....Pages 159-172
Role of subgenomic minus-strand RNA in coronavirus replication....Pages 173-180
Common replication strategies emerging from the study of diverse groups of positive-strand RNA viruses....Pages 181-194
Preferential replication of defective turnip yellow mosaic virus RNAs that express the 150-kDa protein in cis ....Pages 195-204
In vivo transfection by hepatitis A virus synthetic RNA....Pages 205-209
Front Matter....Pages 211-211
Recombination between Sindbis virus RNAs....Pages 213-220
Homologous RNA recombination allows efficient introduction of site-specific mutations into the genome of coronavirus MHV-A59 via synthetic co-replicating RNAs....Pages 221-230
Targeting of the site of nonhomologous genetic recombination in brome mosaic virus....Pages 231-238
Natural recombination in bovine viral diarrhea viruses....Pages 239-244
Sequences at the ends of RNA-2 of I6, a recombinant tobravirus....Pages 245-251
Front Matter....Pages 253-253
Identification and characterization of host factor interactions with cis -acting elements of rubella virus RNA....Pages 255-267
Interaction of cellular proteins with the poliovirus 5′ noncoding region....Pages 269-277
IRES-controlled protein synthesis and genome replication of poliovirus....Pages 279-289
Analysis of hepatitis A virus translation in a T7 polymerase-expressing cell line....Pages 291-298
Purification and characterization of the U-particle, a cellular constituent whose synthesis is stimulated by Mengovirus infection....Pages 299-306
B-lymphocytes are predominantely involved in viral propagation of hepatitis C virus (HCV)....Pages 307-316
Front Matter....Pages 317-317
Folding of the mouse hepatitis virus spike protein and its association with the membrane protein....Pages 319-328
Assembly and entry mechamisms of Semliki Forest virus....Pages 329-338
The interactions of the flavivirus envelope proteins: implications for virus entry and release....Pages 339-348
Coronavirus polyprotein processing....Pages 349-358
Processing of dengue type 4 and other flavivirus nonstructural proteins....Pages 359-368
Nuclear targeting of Semliki Forest virus nsP2....Pages 369-377
Front Matter....Pages 379-379
Replication and translation of cowpea mosaic virus RNAs are tightly linked....Pages 381-392
Alphavirus positive and negative strand RNA synthesis and the role of polyproteins in formation of viral replication complexes....Pages 393-405
Nodavirus RNA replication: mechanism and harnessing to vaccinia virus recombinants....Pages 407-416
Front Matter....Pages 379-379
Molecular characterization of Borna virus RNA....Pages 417-427
Genomic organization and expression of astroviruses and caliciviruses....Pages 429-439
Lelystad virus belongs to a new virus family, comprising lactate dehydrogenase-elevating virus, equine arteritis virus, and simian hemorrhagic fever virus....Pages 441-448
Front Matter....Pages 449-449
Recognition of cellular receptors by bovine coronavirus....Pages 451-459
Mouse hepatitis virus receptors: more than a single carcinoembryonic antigen....Pages 461-471
Host-cell receptors for Sindbis virus....Pages 473-484
Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter....Pages 485-494
Front Matter....Pages 495-495
Comparative studies of T = 3 and T = 4 icosahedral RNA insect viruses....Pages 497-512
Retroviral RNA packaging: a review....Pages 513-522
Structural studies of viruses by electron cryomicroscopy....Pages 523-529
Crystallographic and cryo EM analysis of virion-receptor interactions....Pages 531-541
Assembly of tobacco mosaic virus and TMV-like pseudovirus particles in Escherichia coli ....Pages 543-558