Phytochemistry of Plants of Genus Cassia

Cover
Half Title
Series Page
Title Page
Copyright Page
Table of Contents
Preface
Acknowledgements
Authors
List of Abbreviations and Units
Abstract
1. Introduction
	1.1. Geographical Distribution of Genus Cassia
	1.2. Phytography of Genus Cassia
	1.3. Phytochemistry of Genus Cassia
		1.3.1. Leaves
		1.3.2. Root
		1.3.3. Stem Bark
		1.3.4. Seed
	1.4. Pharmacological Activities of Genus Cassia
	1.5. Traditional Uses of Genus Cassia
	1.6. Introduction of Selected Cassia Species
		1.6.1. Cassia Auriculata
			1.6.1.1. Botany
			1.6.1.2. Medicinal Property
			1.6.1.3. Phytochemistry
		1.6.2. Cassia Fistula
			1.6.2.1. Botany
			1.6.2.2. Medicinal Property
			1.6.2.3. Phytochemistry
		1.6.3. Cassia Occidentalis
			1.6.3.1. Botany
			1.6.3.2. Medicinal Property
			1.6.3.3. Phytochemistry
		1.6.4. Cassia Siamea
			1.6.4.1. Botany
			1.6.4.2. Medicinal Property
			1.6.4.3. Phytochemistry
2. Qualitative and Quantitative Determination of Bioactive Phytochemicals in Selected Cassia Species Using HPLC-ESI-QTOF-MS and UPLC-ESI-QqQLIT-MS/MS
	2.1. Plant Material and Chemicals
	2.2. Extraction and Sample Preparation
	2.3. Preparation of Standard Solution
	2.4. HPLC-ESI-QTOF-MS Conditions
		2.4.1. Instrumentation
		2.4.2. HPLC Condition
		2.4.3. Mass Spectrometric Conditions
	2.5. UPLC- ESI-QqQLIT-MS/MS Conditions
		2.5.1. Instrumental Parameters
		2.5.2. UPLC Condition
		2.5.3. Mass Spectrometric Conditions
		2.5.4. Source Parameters Optimized for Negative Mode
		2.5.5. Compound-Dependent Parameters
	2.6. Principal Component Analysis
	2.7. Optimization of UPLC conditions
	2.8. Optimization of MS/MS Conditions
	2.9. Analytical Method Validation
		2.9.1. Linearity, LOD and LOQ
		2.9.2. Precision, Stability and Recovery
	2.10. Qualitative Analysis of Cassia Occidentalis Samples
	2.11. Quantitative Analysis of Cassia Species Samples
	2.12. Principal Component Analysis to Study Chemical Variations
3. In-vitro Anti-Proliferative Screening in Selected Cassia Species
	3.1. Plant Material
	3.2. Extraction and Sample Preparation
	3.3. Cell Lines and Anti-Proliferative Assay
	3.4. In-vitro Anti-Proliferative Activity Evaluation
4. Bone Regeneration Effect of Cassia occidentalis Linn. Extract and Its Isolated Compounds
	4.1. Bone Healing Property of Cassia occidentalis
	4.2. Osteoporosis and Arthritis
	4.3. The Effects of CO Extract Fraction and Formulation
	4.4. Effects of Compounds Derived from CO Extract
		4.4.1. Apigenin
		4.4.2. Emodin
		4.4.3. Luteolin
		4.4.4. Caryophyllene
		4.4.5. Kaempferol
		4.4.6. Quercetin
5. Conclusions
References
Index