Physiology of Membrane Disorders

Front Matter....Pages i-xxvii
Front Matter....Pages 1-1
The Anatomy of Biological Interfaces....Pages 3-24
Composition and Dynamics of Lipids in Biomembranes....Pages 25-44
Membrane Proteins....Pages 45-55
Front Matter....Pages 57-57
The Nature and Limitations of Electron Microscopic Methods in Biology....Pages 59-82
Isolation and Characterization of Biological Membranes....Pages 83-92
Absorption and Optical Rotation Spectra of Biological Membranes....Pages 93-109
Mathematical Models of Membrane Transport Processes....Pages 111-131
Application of Tracers to the Study of Membrane Transport Processes....Pages 133-150
Principles of Electrical Methods for Studying Membrane Movements of Ions....Pages 151-165
The Study of Transport and Enzymatic Processes in Reconstituted Biological Systems....Pages 167-173
Front Matter....Pages 175-175
Principles of Water and Nonelectrolyte Transport across Membranes....Pages 177-190
Anion Transport in Erythrocytes....Pages 191-220
Active Transport of Na + and K + by Red Blood Cells....Pages 221-234
Weak Electrolyte Transport across Biological Membranes....Pages 235-247
Ion Permeation in Cell Membranes....Pages 249-272
Processing and Sorting of Proteins Synthesized in the Endoplasmic Reticulum....Pages 273-281
Ion-Coupled Transport of Organic Solutes across Biological Membranes....Pages 283-294
Bioenergetics of Membrane Transport Processes....Pages 295-310
Regulation of Cellular Volume....Pages 311-328
Cell-to-Cell Communication....Pages 329-343
Front Matter....Pages 175-175
Genes and Membranes....Pages 345-354
The Interaction of Hormones with Biological Membranes....Pages 355-367
Modification of Membrane Function by Drugs....Pages 369-383
Front Matter....Pages 385-385
Active Transport in Escherichia Coli From Membrane to Molecule....Pages 387-407
Acidification of Intracellular Organelles....Pages 409-422
Intracellular pH Regulation....Pages 423-435
Properties of Ionic Channels in Excitable Membranes....Pages 437-448
Ion Movements in Skeletal Muscle in Relation to the Activation of Contraction....Pages 449-468
Excitable Tissues....Pages 469-490
Ion Transport through Ligand-Gated Channels....Pages 491-516
Front Matter....Pages 517-517
Cellular Models of Epithelial Ion Transport....Pages 519-534
Ion Transport by Gastric Mucosa....Pages 535-558
Ion and Water Transport in the Intestine....Pages 559-596
The Uptake of Lipids into the Intestinal Mucosa....Pages 597-608
Mechanisms of Bile Secretion and Hepatic Transport....Pages 609-636
The Regulation of Glomerular Filtration Rate in Mammalian Kidneys....Pages 637-667
The Proximal Nephron....Pages 669-700
The Effects of ADH on Salt and Water Transport in the Mammalian Nephron....Pages 701-711
Urinary Concentrating and Diluting Processes....Pages 713-726
Transport Functions of the Distal Convoluted Tubule....Pages 727-750
Front Matter....Pages 517-517
The Respiratory Epithelium....Pages 751-766
Front Matter....Pages 767-767
The Cellular Basis of Ischemic Acute Renal Failure....Pages 769-784
Genetic Variants Affecting the Structure and Function of the Human Red Cell Membrane....Pages 785-814
Inherited Membrane Disorders of Muscle....Pages 815-824
Disorders of Muscle....Pages 825-839
Pathophysiology of Cardiac Arrhythmias....Pages 841-859
Pathophysiology of Peptic Ulcer Disease....Pages 861-871
Malabsorption Syndromes....Pages 873-885
Pathophysiology of Calcium Absorptive Disorders....Pages 887-906
Cystic Fibrosis....Pages 907-917
Disorders of Glomerular Filtration....Pages 919-938
The Hypertonic and Hypotonic Syndromes....Pages 939-956
Disorders of Proton Secretion by the Kidney....Pages 957-983
Cystinosis and the Fanconi Syndrome....Pages 985-997
Renal Tubular Defects in Phosphate and Amino Acid Transport....Pages 999-1023
Pulmonary Edema....Pages 1025-1039
Back Matter....Pages 1041-1066