Physico-Chemical Aspects of Drug Action. Proceedings of the Third International Pharmacological Meeting

Content: 
PROCEEDINGS OF THE FIRST INTERNATIONAL PHARMACOLOGICAL MEETING, STOCKHOLM, 22–25 AUGUST, 1961, Page ii
Front Matter, Page iii
Copyright, Page iv
LIST OF AUTHORS AND PARTICIPANTS, Pages vii-ix
INTRODUCTORY REMARKS, Pages 1-4, E.J. ARIëNS
PHARMACOKINETICS AS A BASIC MEDICAL PROBLEM, Pages 5-32, L. DETTLI, P. SPRING
KINETICS AND IMPLICATIONS OF DISSOLUTION RATE. LIMITED GASTROINTESTINAL ABSORPTION OF DRUGS, Pages 33-62, GERHARD LEVY
PHARMACOKINETICS AND DOSE-CONCENTRATION RELATIONSHIPS, Pages 63-113, EKKEHARD KRüGER-THIEMER
THE TIME COURSE OF THE BIOLOGICAL RESPONSE TO DRUGS: A MATHEMATICAL TREATMENT, Pages 115-126, VLADIMíR PLIŠKA
EMPIRICAL EQUATIONS FOR CORRELATING BIOLOGICAL EFFICIENCY OF ORGANIC COMPOUNDS, Pages 127-139, R. ZAHRADNíK, K. BOČEK, J. KOPECKý
THE USE OF SUBSTITUENT CONSTANTS IN STRUCTURE-ACTIVITY STUDIES, Pages 141-167, CORWIN HANSCH
MOLECULAR BASIS FOR THE ACTION OF CHEMOTHERAPEUTIC DRUGS, STRUCTURE-ACTIVITY STUDIES ON SULFONAMIDES, Pages 169-180, JOACHIM K. SEYDEL
INFLUENCE OF DIFFERENT DRUGS ON THE SULFONAMIDES SERUM BINDING AND ON SULFONAMIDE AQUEOUS HUMOR LEVELS, Pages 181-187, E. GENAZZANI, G. PAGNINI, R.DI CARLO
THE STUDY OF DRUG BINDING SITES BY NUCLEAR MAGNETIC RELAXATION, Pages 189-191, OLEG JARDETZKY
DRUG-RECEPTOR INTERACTIONS IN METHEMOGLOBINS AND IN HEMIN MODELS, Pages 193-205, W. SCHELER
PATTERNS OF LIGAND-INDUCED CHANGES ON A RECEPTOR SURFACE: THE WATER EXTRUSION HYPOTHESIS, Pages 207-236, B. BELLEAU
BIOLOGICAL DRUG PARAMETERS FOR STUDIES OF THE RELATIONSHIP BETWEEN STRUCTURE AND ACTIVITY: THEIR SIGNIFICANCE AND LIMITED VALUE. METHODS FOR ESTIMATION, Pages 237-260, JACQUES M. VAN ROSSUM
MATHEMATICAL TREATMENT OF TWO-POINT ATTACHMENT BETWEEN DRUG AND RECEPTOR, Pages 261-269, ALEXANDER GERO
CHEMICAL STRUCTURE AND BIOLOGICAL ACTIVITY. SOME GENERAL PRINCIPLES, Pages 271-281, E.J. ARIëNS, A.M. SIMONIS
MOLECULAR PROPERTIES AND BIOLOGICAL ACTIVITY OF CATECHOLAMINES AND CERTAIN RELATED COMPOUNDS, Pages 283-294, P. PRATESI, E. GRANA, L. VILLA
SOME ELECTRONIC ASPECTS OF PHARMACOLOGY, Pages 295-303, W.C. HOLLAND
DIARYLCARBINOL ETHERS: STRUCTURE ACTIVITY RELATIONSHIPS. A PHYSICO-CHEMICAL APPROACH, Pages 305-325, W.TH. NAUTA, R.F. REKKER, A.F. HARMS
QUANTUM MECHANICALLY DERIVED ELECTRONIC DISTRIBUTIONS IN THE CONFORMERS OF 2-PAM, Pages 327-354, WALLY GIORDANO, JON R. HAMANN, JEROME J. HARKINS, JOYCE J. KAUFMAN
A MOLECULAR BASIS FOR THE ACTION OF CERTAIN DRUGS IN THE CENTRAL NERVOUS SYSTEM, Pages 355-375, A. SHULMAN, GLENDA M. LAYCOCK, A.S. BUCHANAN
INDEX, Pages 377-385