Perinatal Neuropathology

Cover
Half-title page
Title page
Copyright page
Contents
Preface
Acknowledgments
List of Abbreviations
Section I Techniques and Practical Considerations
	Approach to Autopsy of the Perinatal Nervous System
		Chapter
1 Clinical Considerations
		Chapter
2 Imaging
		Chapter
3 External Exam of the Fetus/Infant
		Chapter
4 Autopsy and Research Consent
	section Ancillary Studies
		Chapter
5 Microbiology
		Chapter
6 Cytogenetics
		Chapter
7 Metabolic Studies
		Chapter
8 Toxicology
	section Prosection Techniques
		Chapter 9 Brain Prosection
		Chapter 10 Spinal Cord Prosection
		Chapter
11 Neuromuscular Specimens
		Chapter
12 Eye Specimens
	section Tissue Selection
		Chapter
13 Selection of Brain Areas for Microscopic Examination
		Chapter
14 Technical Considerations in Perinatal CNS Tissue Processing
		Chapter
15 Staining Techniques
	section Reporting
		Chapter
16 Formulation of Diagnosis
		Chapter
17 Reporting Templates
		Chapter
18 Medicolegal Considerations
Section 2 Human Nervous System Development
	Neuroanatomic Site Development
		Chapter
19 Human Nervous System Development: Embryonic and Early Fetal Events
		Chapter
20 Cerebral Cortex, Including Germinal Matrix
		Chapter
21 White Matter, Including Myelination
		Chapter
22 Cerebellum: Development of the Rhombic Lip, Cerebellar Cortex, Dentate Nucleus
		Chapter
23 Spinal Cord
		Chapter
24 Skeletal Muscle and Peripheral Nerve
		Chapter
25 Fetal and Infant Eye
	section Growth Parameters
		Chapter
26 Head Size and Brain Weight
Section 3 Stillbirth
	Autolysis, Artifacts, and Stillbirths
		Chapter
27 Autolysis and Artifacts
	section Stillbirths
		Chapter
28 Neuropathology of Stillbirth
Section 4 Disruptions / Hypoxic-Ischemic Injury
	Cellular Responses
		Chapter
29 Neuronal Death
		Chapter
30 Macroglial Reactions
		Chapter
31 Inflammatory Responses
	section Gray Matter
		Chapter
32 Supratentorial Gray Matter Damage and Disruptions
		Chapter
33 Brainstem and Spinal Cord Disruptions
	section White Matter
		Chapter
34 Periventricular Leukomalacia and Diffuse White Matter Injury
	section Germinal Matrix
		Chapter
35 Periventricular and Intraventricular Brain Hemorrhage
	section Cerebellum
		Chapter
36 Cerebellar Lesions
Section 5 Malformations
	Neural Tube Defects and Patterning Defects
		Chapter
37 Defects of Neural Tube Closure and Axial Mesodermal Defects
		Chapter
38 Disorders of Early Midline Patterning
	Section Hydrocephalus
		Chapter
39 Fetal and Perinatal Hydrocephalus
	section Neuronal Migration Disorders
		Chapter
40 Cerebral Cortical Migration Disorders
	section Genetic Syndromes and Phakomatoses
		Chapter
41 Fragile X Syndrome
		Chapter 42 Down Syndrome - Trisomy 21
		Chapter 43 Edwards Syndrome - Trisomy 18
		Chapter 44 Patau Syndrome - Trisomy 13
		Chapter
45 Tuberous Sclerosis Complex
		Chapter
46 Sturge-Weber Syndrome
		Chapter
47 Neurocutaneous Melanosis
Section 6 Perinatal Neurooncology
	Chapter
48 Congenital and Perinatal Brain Tumors
Section 7 Spinal and Neuromuscular Disorders
	Arthrogryposis
		Chapter
49 Arthrogryposis Multiplex Congenita
	Section Spinal Muscular Atrophy
		Chapter
50 Spinal Muscular Atrophy (SMA)
	Section Early-Onset Hereditary Neuropathies
		Chapter
51 Charcot-Marie-Tooth (CMT) Neuropathies
	Section Congenital Muscle Disorders
		Chapter
52 Congenital Myasthenic Syndromes
		Chapter
53 Congenital Muscular Dystrophies
		Chapter
54 Congenital Myopathies
		Chapter
55 Other Congenital Muscle Disorders
Section 8 Eye Disorders
	Chapter
56 Congenital Eye Malformations and Deformations
Section 9 Infections
	In Utero Infections
		Chapter
57 Congenital Viral, Bacterial, and Parasitic Infections
	Section Peri- and Postnatal Infections
		Chapter
58 Meningitis and Encephalitis
Section 10 Metabolic / Toxic Disorders: Storage Diseases
	Storage Diseases
		Chapter
59 Lysosomal Disorders
		Chapter
60 Peroxisomal Disorders
	Section Kernicterus
		Chapter
61 Clinicopathological Features of Kernicterus
	Section Mitochondrial Diseases
		Chapter
62 Clinicopathological Features of Mitochondrial Diseases
	Section Maternal Toxin Exposure
		Chapter
63 Ethanol and Other Agents
Section 11 Forensic Neuropathology
	Trauma
		Chapter
64 Birth Trauma
		Chapter
65 Accidental and Nonaccidental Death
	Section Sudden Unexpected Death
		Chapter
66 Sudden Unexpected Death in Infancy and Childhood
Appendix 1 Technical Considerations in Perinatal CNS
Index