Pediatric Inflammatory Bowel Disease

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Genetics of Inflammatory Bowel Diseases....Pages 3-14
The Intestinal Immune System During Homeostasis and Inflammatory Bowel Disease....Pages 15-30
Cytokines and Inflammatory Bowel Disease....Pages 31-43
The Gut Microbiota and Inflammatory Bowel Disease....Pages 45-54
Immune Dysregulation Associated with Very Early-Onset Inflammatory Bowel Disease....Pages 55-67
Front Matter....Pages 69-69
Epidemiology of Pediatric Inflammatory Bowel Disease....Pages 71-86
The Natural History of Crohn Disease in Children....Pages 87-94
Natural History of Ulcerative Colitis in Children....Pages 95-101
Natural History of Pediatric Indeterminate Colitis....Pages 103-107
Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease....Pages 109-116
Liver Disease in Pediatric Inflammatory Bowel Disease....Pages 117-134
Growth Impairment in Pediatric Inflammatory Bowel Disease....Pages 135-153
Inflammatory Bowel Diseases and Skeletal Health....Pages 155-170
Puberty and Pediatric-Onset Inflammatory Bowel Disease....Pages 171-179
Classification of Inflammatory Bowel Disease in Children....Pages 181-191
Front Matter....Pages 193-193
The History and Physical Exam....Pages 195-198
Differential Diagnosis of Inflammatory Bowel Disease....Pages 199-209
Laboratory Evaluation of Inflammatory Bowel Disease....Pages 211-224
Fecal Biomarkers in Inflammatory Bowel Disease....Pages 225-232
Radiologic Evaluation of Pediatric Inflammatory Bowel Disease....Pages 233-246
Front Matter....Pages 193-193
Endoscopy and Inflammatory Bowel Disease....Pages 247-271
The Pathology of Chronic Inflammatory Bowel Disease....Pages 273-286
Video Capsule Endoscopy in Inflammatory Bowel Disease....Pages 287-297
Bone Health in Pediatric Inflammatory Bowel Disease....Pages 299-314
Front Matter....Pages 315-315
5-Aminosalicylate Therapy....Pages 317-324
Antibiotic Therapy....Pages 325-331
Nutritional Management of Inflammatory Bowel Disease....Pages 333-356
Probiotic Therapy....Pages 357-367
Corticosteroids....Pages 369-373
6-Mercaptopurine Therapy....Pages 375-381
Methotrexate....Pages 383-388
Infliximab Therapy for Pediatric Crohn Disease and Ulcerative Colitis....Pages 389-400
Anti-TNF Biologic Therapies Other than Infliximab....Pages 401-416
Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease....Pages 417-424
New Non-anti-TNF-α Biological Therapies for the Treatment of Inflammatory Bowel Disease....Pages 425-450
Medical Treatment of Perianal Crohn’s Disease Fistulae....Pages 451-464
Treatment of Acute Severe Ulcerative Colitis....Pages 465-472
Dietary Therapies for Inflammatory Bowel Disease....Pages 473-483
Complementary and Alternative Therapies....Pages 485-494
Front Matter....Pages 495-495
Management of Intra-abdominal Complications of Inflammatory Bowel Disease....Pages 497-505
Front Matter....Pages 495-495
Surgical Management of Crohn Disease in Children....Pages 507-517
Surgical Treatment of Ulcerative Colitis....Pages 519-531
Postoperative Surveillance and Management of Crohn’s Disease....Pages 533-541
Pouchitis After Ileal Pouch-Anal Anastomosis....Pages 543-555
Enteral Feeding Devices and Ostomies....Pages 557-567
Front Matter....Pages 569-569
Clinical Indices for Pediatric Inflammatory Bowel Disease Research....Pages 571-590
Clinical Trials (Clinical Perspective)....Pages 591-592
Clinical Trials (Industry/Regulatory Perspective)....Pages 593-601
Front Matter....Pages 603-603
Infectious Complications of Pediatric Inflammatory Bowel Disease....Pages 605-614
Psychological Aspects of Inflammatory Bowel Disease in Children and Adolescents....Pages 615-623
Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease....Pages 625-638
Irritable Bowel Syndrome and Functional GI Disorders in Inflammatory Bowel Disease....Pages 639-649
Inflammatory Bowel Disease in Pregnancy....Pages 651-662
Immunizations in the Child with Inflammatory Bowel Disease....Pages 663-668
Malignant Tumors Arising in Inflammatory Bowel Disease....Pages 669-683
Quality Improvement in Inflammatory Bowel Disease....Pages 685-695
Fostering Self-Management and Patient Activation....Pages 697-702
Advocacy for Pediatric Patients with IBD....Pages 703-713
Legislative Advocacy....Pages 715-720
Transition from Pediatric to Adult Care....Pages 721-729
Back Matter....Pages 731-754