Patient Derived Tumor Xenograft Models. Promise, Potential and Practice

Content: 
Front Matter,Copyright,List of Contributors,Biographies,Foreword,PrefaceEntitled to full textSection I: Mouse Xenograft Models of CancerChapter 1 - PDX Models: History and Development, Pages 1-12, S.P.S. Pillai, R.K. Uthamanthil
Chapter 2 - History of Mouse Cancer Models, Pages 15-23, L.R. Hill, P.T. Tinkey
Chapter 3 - Challenges and Limitations of Mouse Xenograft Models of Cancer, Pages 25-36, B.W. Simons, C. Brayton
Chapter 4 - Tumor Heterogeneity, Pages 37-55, J.W. Cassidy, A. Bruna
Chapter 5 - Immunodeficient Mice: The Backbone of Patient-Derived Tumor Xenograft Models, Pages 57-73, D.K. Hirenallur-Shanthappa, J.A. Ramírez, B.M. Iritani
Chapter 6 - Humanized Mice and PDX Models, Pages 75-89, J. Eswaraka, A. Giddabasappa
Chapter 1 - Regulations of Patient-Derived Xenografts, Pages 93-108, S. Thompson-Iritani, S.C. Schmechel
Chapter 2 - Acquisition and Storage of Clinical Samples to Establish PDX Models, Pages 109-118, M. Mattar, O. Abdel-Wahab, E. de Stanchina
Chapter 3 - Methodologies for Developing and Maintaining Patient-Derived Xenograft Mouse Models, Pages 119-134, M. Mattar, O. Abdel-Wahab, J.T. Poirier, M. Scaltriti, E. de Stanchina
Chapter 4 - Pathology of Patient-Derived Xenograft Tumors, Pages 135-148, J.-J. Fontaine, E. Marangoni, S. Chateau-Joubert, J.-L. Servely
Chapter 5 - Genetic Profiling of Tumors in PDX Models, Pages 149-159, J.T. Poirier
Chapter 6 - Running a PDX Core Laboratory or a PDX Support Program, Pages 161-172, A. Krivtsov, M. Mattar, R.K. Uthamanthil, E. de Stanchina
Chapter 7 - Veterinary Care, Pages 173-185, T. Brabb, P.T. Tinkey
Chapter 8 - Occupational Health and Safety, Pages 187-202, L.A. Colby, E. Corwin
Chapter 1 - Pediatric and Adult Brain Tumor PDX Models, Pages 205-216, A.D. Strand, E. Girard, J.M. Olson
Chapter 2 - Patient-Derived Xenograft Models of Prostate Tumors, Pages 217-228, P.J. Russell, E.D. Williams, R. Taylor, M.G. Lawrence, G. Risbridger
Chapter 3 - Patient-Derived Xenograft Model of Pancreatic Cancer, Pages 229-241, M.V. Rios Perez, J.B. Fleming
Chapter 4 - Modeling Breast Cancer Heterogeneity With Patient-Derived Xenografts, Pages 243-256, K.W. Evans, N. Paez-Arango, A. Akcakanat, E. Yuca, F. Meric-Bernstam
Chapter 5 - Patient-Derived Xenograft Models of Ovarian/Gynecologic Tumors, Pages 257-271, L. Liang, I. Mercado-Uribe, N. Niu, Y. Jiang, W. Cheng, J. Zhang, G.B. Mills, C. Scott, A.K. Sood, J. Liu
Chapter 6 - Patient-Derived Xenografts From Lung Cancer and Their Potential Applications, Pages 273-289, L. Wang, R. Zhang, B. Fang
Chapter 7 - PDX Models of Colorectal Tumors, Pages 291-304, J.P. MacKeigan, D.M. Burgenske
Chapter 8 - Patient-Derived Tumor Xenografts in Hematologic Disorders, Pages 305-339, M. Pizzi, G. Inghirami
Chapter 9 - Patient-Derived Xenografting of Human Melanoma, Pages 341-363, S.E. Boyle, C.G. Fedele, M. Shackleton
Chapter 10 - Advances in Organoid Culturing of Patient-Derived Tumors, Pages 365-375, S.D. Kaffenberger, Y. Chen
Chapter 1 - Global Practices in PDX Programs, Pages 379-407, G.Y. Ho, C.L. Scott, K. Pham
Chapter 2 - Role of Companies and Corporations in the Development and Utilization of PDX Models, Pages 409-426, J. Snyder, O. Duchamp, K. Paz, P. Sathyan
Chapter 1 - Patient-Derived Tumor Xenograft: Present and Future Challenges and Applications, Pages 429-451, G. Inghirami, P.T. Tinkey, E. de Stanchina, R.K. Uthamanthil
Index, Pages 453-460