Pathology, Prevention and Therapeutics of Neurodegenerative Disease

Front Matter ....Pages i-ix
 Alpha Synuclein and Parkinson’s Disease  (Arti Parihar, Priyanka Parihar, Isha Solanki, Mordhwaj S. Parihar)....Pages 1-14
 Molecular Mechanisms of Neurodegeneration: Insights from the Studies of Genetic Model of Parkinson’s Disease  (Nisha R. Dhanushkodi, M. Emdadul Haque)....Pages 15-29
 Pathology and Cell-Based Therapy of Parkinson’s Disease  (So Young Kim, Sung S. Choi, Dong-Seok Lee, Seung Hoon Lee, Sang Hoon Cha, Hong J. Lee)....Pages 31-38
 The Role of p53 in Alzheimer’s Disease: Impact on Tau Pathology  (Maja Jazvinšćak Jembrek, Katy Newberg, Goran Šimić)....Pages 39-48
 Pathophysiological Mechanisms of Huntington’s Disease  (Zuleide M. Ignácio, João Quevedo, Gislaine Z. Réus)....Pages 49-60
 Glutamate in Amyotrophic Lateral Sclerosis: An Ageless Contestant  (Alida Spalloni, Michele Nutini, Patrizia Longone)....Pages 61-71
 Inherited Neurodegenerative Disorders  (Dulika S. Sumathipala, Vajira H. W. Dissanayake)....Pages 73-79
 Astrocytes and the Synucleinopathies  (Andrew O. Koob, Paola Sacchetti)....Pages 81-102
 The Diagnosis of Parkinson’s Disease: Current Clinical Practice and Future Trends  (Roberto López Blanco, Álvaro Sánchez Ferro)....Pages 103-116
 Clinical Symptomatology of Huntington’s Disease  (Jan Roth)....Pages 117-131
 Diagnosis of Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Spectrum  (Vanesa Pytel, Jordi A. Matías-Guiu)....Pages 133-141
 Nanocarriers for Diagnosis and Imaging of Neurodegenerative Diseases  (Mine Silindir-Gunay, A. Yekta Ozer)....Pages 143-150
 Parkinson Disease Therapies and Drugs  (Rodolphe Hajj)....Pages 151-158
 Therapeutic Application of Stem Cell and Gene Therapy in Parkinson’s Disease  (Charlotte Palmer, Raquel Coronel, Adela Bernabeu-Zornoza, Isabel Liste)....Pages 159-171
 Targeting Glucocorticoid Receptors: A New Avenue for Alzheimer’s Disease Therapy  (Geoffrey Canet, Nathalie Chevallier, Véronique Perrier, Catherine Desrumaux, Laurent Givalois)....Pages 173-183
 Multifarious Therapeutic Avenues for Alzheimer’s Disease  (Magisetty Obulays)....Pages 185-190
 Treatment Paradigms in Huntington’s Disease  (Pushkar Kulkarni, Uday Saxena)....Pages 191-196
 Management of HD: Insight into Molecular Mechanisms and Potential Neuroprotective Drug Strategies  (Puneet Kumar, Sumit Jamwal, Anil Kumar)....Pages 197-206
 Amyotrophic Lateral Sclerosis: Current Therapeutic Perspectives  (Vijay Kumar, Tara Kashav, Md. Imtaiyaz Hassan)....Pages 207-224
 Mechanistic Insights into Neurodegenerative Diseases: The Potential for the Development of Novel Therapeutics  (Medhane Cumbay, Michael LaFontaine, Sage Arbor)....Pages 225-240
 Neural Stem Cell-Based Therapeutic Approaches for Brain Repair  (Cláudia Saraiva, Tiago Santos, Liliana Bernardino)....Pages 241-252
 Recent Advances in the Antioxidant Therapies for Alzheimer’s Disease: Emphasis on Natural Antioxidants  (Namrata Singh, Kallol K. Ghosh)....Pages 253-263
 Dietary Directions Against Dementia Disorders  (Helmut M. Hügel, Anthony R. Lingham, Neale Jackson, Trevor Rook)....Pages 265-278
 Use of Herbal Products/Alternative Medicines in Neurodegenerative Diseases (Alzheimer’s Disease and Parkinson’s Disease)  (Omar M. E. Abdel-Salam)....Pages 279-301