Pancreatic Disease: State of the Art and Future Aspects of Research

Front Matter....Pages I-XIII
Front Matter....Pages 1-1
Acute Pancreatitis: Mechanisms of Cell Injury — Genetics....Pages 3-13
Events Inside the Pancreatic Acinar Cell in Acute Pancreatitis: Role of Secretory Blockade, Calcium Release, and Dehydration in the Initiation of Trypsinogen Activation and Autodigestion....Pages 14-23
Immunological Mechanisms in Acute Pancreatitis....Pages 24-35
Mechanisms in Cellular Injury....Pages 36-38
Acute Pancreatitis: Bacterial Translocation and Pancreatic Infections....Pages 39-54
Staging and Early Nasoenteral Feeding in Acute Pancreatitis....Pages 55-65
Acute Pancreatitis: Medical and Endoscopic Treatment....Pages 66-77
Surgical Treatment of Acute Pancreatitis....Pages 78-89
Front Matter....Pages 91-91
Chronic Pancreatitis: Do Different Etiologies (Alcohol, Obstruction) Invoke Different Mechanisms?....Pages 93-101
Exocrine Pancreatic Secretion, Pain, and Malabsorption....Pages 102-111
Intestinal Transit of Chyme and its Regulatory Role: Clinical Implications....Pages 112-120
Treatment of Exocrine Pancreatic Insufficiency in Chronic Pancreatitis....Pages 121-131
Mechanisms of Fibrosis and Potential Antifibrotic Agents....Pages 132-139
Mechanisms of Pain and its Medical Management, Including Neurolytic Treatments....Pages 140-145
Endoscopic Treatment of Pain and Complications of Chronic Pancreatitis....Pages 146-154
Surgical Treatment of Chronic Pancreatitis....Pages 155-164
Front Matter....Pages 165-165
Genetics and Molecular Pathology of Cystic Fibrosis....Pages 167-179
Treatment of Gastrointestinal Manifestations in Cystic Fibrosis....Pages 180-192
Is Idiopathic Chronic Pancreatitis Cystic Fibrosis?....Pages 193-201
Front Matter....Pages 203-203
Growth Factors and Transcription Factors in Pancreatic Cancer....Pages 205-221
Front Matter....Pages 203-203
Biological Approaches to the Therapy of Pancreatic Cancer....Pages 222-229
Pancreatic Cancer: Preclinical Development of an Experimental Treatment Strategy Using Retinoids and Interferon-alpha....Pages 230-237
Aspects of Radical Surgery for Exocrine Cancer of the Pancreatic Head....Pages 238-249
Front Matter....Pages 251-251
Lessons Learned about Pancreatitis and Pancreatic Cancer from Epidemiological Studies....Pages 253-262
Back Matter....Pages 263-272