Pancreatic Disease: Basic Science and Clinical Management

Front Matter....Pages i-xx
Front Matter....Pages 1-1
Epidemiology of Pancreatic Neuroendocrine Tumours....Pages 5-17
Quality of Life Issues Identified by Healthcare Workers and Patients with Metastatic Carcinoid/Neuroendocrine Tumours....Pages 18-22
Diagnosis and Localisation of Insulinoma....Pages 23-30
GI Hormone Producing Tumours: Syndromes and Treatment Options....Pages 31-53
Progress by Collaboration: ESPAC Studies....Pages 57-69
Gemcitabine: a Systematic Review....Pages 70-78
Farnesyl Protein Transferase Inhibitors in Pancreatic Cancer....Pages 79-92
Novel Alternatives to Chemotherapy in Advanced Disease: Gastrin Antibodies....Pages 93-98
Novel Alternatives to Chemotherapy in Advanced Disease: Gene Transfer....Pages 99-120
Suicide Gene Therapy for Pancreatic Cancer....Pages 121-130
Pancreatic Cystic Lesions and Neoplasms....Pages 133-143
Pancreatic Involvement in Von Hippel-Lindau Disease....Pages 144-152
Intraductal Papillary Mucinous Tumours of the Pancreas....Pages 153-160
Front Matter....Pages 161-161
Endoscopic Ultrasound in the Diagnosis of Chronic Pancreatitis and Pancreatic Cancer....Pages 163-173
Natural Course of Chronic Pancreatitis....Pages 174-189
Autoimmune Pancreatitis....Pages 190-199
What’s New in Pancreatic Stellate Cell Biology?....Pages 203-225
Pancreatic Stellate Cells and Their Role in Fibrogenesis....Pages 226-239
Factors Influencing Pancreatic Stellate Cell Phenotype and Cell Turnover....Pages 240-247
Acinar-Islet Cell Interactions: Diabetes Mellitus in Chronic Pancreatitis....Pages 251-266
Front Matter....Pages 161-161
Acinar-Islet Interactions: Pancreatic Exocrine Insufficiency in Diabetes Mellitus....Pages 267-278
Front Matter....Pages 279-279
Genetic Basis of Hereditary and Sporadic Pancreatitis....Pages 281-293
Cytokines in Chronic Pancreatitis....Pages 294-299
Cytokine Gene Polymorphisms in Acute Pancreatitis....Pages 300-305
Genetic Polymorphism, the Immune Response and Chronic Pancreatitis....Pages 306-317
Xenobiotic Metabolising Enzymes in Pancreatitis....Pages 318-323
Trypsin Activation and Inhibition in Pancreatitis....Pages 324-339
Front Matter....Pages 341-341
Selecting Patients for Trials and Treatment: Apache-II?....Pages 345-357
Selecting Severe Cases of Acute Pancreatitis for Trials and for Treatment: Enzymes and Activation Peptides....Pages 358-365
Selecting Severe Cases of Acute Pancreatitis on the Basis of Organ Failure....Pages 366-370
Individual Features Related to Severity in Acute Pancreatitis....Pages 371-379
Sterile Necrosis in Acute Necrotizing Pancreatitis: Current Concepts and Management Strategies....Pages 383-389
Management of Infected Pancreatic Necrosis....Pages 390-399
Antibiotics in Acute Pancreatitis....Pages 400-412
Enteral Nutrition in Acute Pancreatitis: Mucosal Barrier....Pages 415-427
Early Enteral Nutrition and Markers of the Inflammatory Response in Severe Acute Pancreatitis....Pages 428-433
Enteral Nutrition in Acute Pancreatitis: Clinical Outcome....Pages 434-438
Front Matter....Pages 439-439
Measurement of Symptoms and Quality of Life in Pancreatic Disease....Pages 441-450
Mechanism of Nociception in Chronic Pancreatitis....Pages 451-455
Bilateral Thoracoscopic Splanchnicectomy in the Management of Pain in Patients with Chronic Pancreatitis....Pages 456-460
Front Matter....Pages 439-439
Nerve Pathways for Pain....Pages 461-467
Pain Management in Chronic Pancreatitis....Pages 468-473
Pancreatic Decompression in Chronic Pancreatitis....Pages 474-478
Back Matter....Pages 481-490