Oxygen Transport to Tissue-V

Front Matter....Pages i-xvi
Front Matter....Pages 1-1
Facilitated Diffusion of Oxygen: Possible Significance in Blood and Muscle....Pages 3-21
Muscle O 2 Gradients from Hemoglobin to Cytochrome: New Concepts, New Complexities....Pages 23-38
Metabolic Rate and Microcirculation....Pages 39-67
Tissue O 2 Supply Under Normal and Pathological Conditions....Pages 69-80
Relationship Between Steady Redox State and Brain Activation-Induced NAD/NADH Redox Responses....Pages 81-100
Front Matter....Pages 101-101
Mathematical Analysis of Transport and Consumption of Molecules in Heterogeneous Brain Tissue (Methodology)....Pages 103-123
Coupled Transport of O 2 and Co 2 Within the Upper Skin Simulated by the Capillary Loop Model....Pages 125-132
Facilitated Diffusion and Electrical Potentials in Protein Solutions with Ionic Species....Pages 133-143
Diffusional Coupling in a Hemoglobin-Free Perfused Capillary-Tissue Structure....Pages 145-160
Front Matter....Pages 161-161
On the Seemingly Diminished Co 2 -Bohr Effect in Hypoxic Chemodenervated Rabbits....Pages 163-173
Oxygen Uptake into the Sheared Flowing Blood: Effects of Red Cell Membranes and Haematocrit....Pages 175-185
Diabetic Oxygen-Hemoglobin Equilibrium Curves Evaluated by Nonlinear Regression of the Hill Equation....Pages 187-198
Improved O 2 Transfer to Tissues During Deep Hypoxia in Rats with a Left-Shifted Blood O 2 Dissociation Curve....Pages 199-208
Front Matter....Pages 209-209
Changes in Cerebral Oxygen Tension and Red Cell Content on Sensory Stimulation....Pages 211-213
Relations Between Po 2 and Neuronal Activity in Hippocampal Slices....Pages 215-226
Response of Gerbil Cerebral Unit Activity to Slowly Declining Tissue Po 2 ....Pages 227-230
Properties of the Spontaneous Fluctuations in Cortical Oxygen Pressure....Pages 231-239
Intraoperative Monitoring of Cortical Surface Oxygen in Sub-arachnoid Haemorrhage....Pages 241-249
Focal Epicerebral Ischemia: Post-Ischemic Tissue Oxygenation with and without Recirculation....Pages 251-260
The Effect of Glucose on the Oxygen Supply of the Blood-Free Perfused Guinea Pig Brain as Measured by Reflection Spectra and Po 2 Histograms....Pages 261-269
Front Matter....Pages 209-209
Oxygen Supply to the Brain Cortex in SHR and Normotensive Rats....Pages 271-279
Local Cytochrome Oxidase Activity in the Cerebral Cortex of the Rat, Histochemically Detected with the Dab-Method: a Micro-Densitometric and Electron Microscope Study....Pages 281-289
Relationship Between Microflow, Local Tissue Po 2 and Extracellular Activities of Potassium and Hydrogen Ions in the Cat Brain During Intraarterial Infusion of Ammonium Acetate....Pages 291-296
Regulation of Microflow in the Cat Brain During Insulin Induced Hypoglycemia....Pages 297-303
Glycolysis and Regulation of Cerebral Blood Flow and Metabolism....Pages 305-314
Contribution of Adenosine to the Regulation of Cerebral Blood Flow: The Role of Calcium Ions in the Adenosine-Induced Cerebrocortical Vasodilatation....Pages 315-325
Effect of DMSO and Barbiturates on Brain Oxygen Distribution....Pages 327-327
Front Matter....Pages 329-329
Local Oxygen Supply and Regional Wall Motion of the Dog’s Heart During Critical Stenosis of the Lad....Pages 331-340
Intramyocardial Oxygen Pressure and Coronary Blood Flow During Experimental Coronary Stenosis....Pages 341-350
Mitochondrial Oxidative Phosphorylation: Tissue Oxygen Sensor for Regulation of Coronary Flow....Pages 351-357
Respiratory Chain O 2 Requirements and the Metabolic Answer to Diffuse Ischemia of Mechanically Overloaded Left Ventricular Myocardium....Pages 359-367
Distribution of Myocardial Glucose Consumption Under Normal Conditions and During Isoprenaline and Dobutamine Infusion....Pages 369-380
Cardiovascular and Metabolic Responses to Carotid Clamping in Anemic Dogs....Pages 381-387
Functional Alteration of Membrane Integrity During Global Ischemia in Perfused Working Rabbit Hearts....Pages 389-402
Effects of Propranolol and Epinephrine on Capillary Plasma Filling and Minimal Intercapillary Distances in the Rat Heart....Pages 403-409
A Comparison of the Methods for Assessment of Myocardial Capillarity....Pages 411-418
Front Matter....Pages 419-419
Deleterious Effects of Oxygen Radicals on Reoxygenated Myocardial Cells....Pages 421-431
Spontaneous Lipid Peroxidation in Rabbit Spermatozoa: A Useful Model for the Reaction of O 2 Metabolites with Single Cells....Pages 433-443
Front Matter....Pages 445-445
A Comparison of Po 2 Histograms from Rabbit Hind-Limb Muscles Obtained by Simultaneous Measurements with Hypodermic Needle Electrodes and with Surface Electrodes....Pages 447-455
Diffusion-Perfusion Relationships in Skeletal Muscle: Models and Experimental Evidence from Inert Gas Washout....Pages 457-465
Front Matter....Pages 445-445
Oxygen Supply of Skeletal Muscle in Experimental Endotoxic Shock....Pages 467-476
Microcirculation and Po 2 in Skeletal Muscle During Respiratory Hypoxia and Stimulation....Pages 477-485
Heterogeneity of Capillary Blood Flow in Skeletal Muscle: Evidence from Local 133 Xe Clearance and Microsphere Trapping....Pages 487-488
Biochemical and 31 P-NMR Studies of the Energy Metabolism in Relation to Oxygen Supply in Rat Skeletal Muscle During Exercise....Pages 489-496
Dependence of O 2 Uptake on Tissue Po 2 : Experiments in Intact Excised Rat Skeletal Muscle....Pages 497-505
Metabolic Adaptation in Response to Intermittent Hypoxia in Rat Skeletal Muscles....Pages 507-513
Local Regulation of Blood Flow....Pages 515-540
Front Matter....Pages 541-541
Flow Dependence and Independence of Oxygen Consumption within the Intestinal Vasculature....Pages 543-549
Effect of Somatostatin on Intestinal Microcirculation and Metabolism....Pages 551-560
Po 2 and pH Measurements within the Rabbit Oviduct Following Tubal Microsurgery: Reanastomosis of Previously Dissected Tubes....Pages 561-570
Studies of Hemorrhagic and Traumatic Shock Influence on Liver Oxygen Tension: Effects of a Single Large Dose of Dexamethasone....Pages 571-582
Correlation Between the Redox State of NAD(P)H and Total Flow in the Perfused Rat Liver....Pages 583-588
Studies on the Ability of Kidney Cells to Recover after Periods of Anoxia....Pages 589-595
Erythropoietin and Intrarenal Oxygenation in Hypercapnic Versus Normocapnic Hypoxemia....Pages 597-609
Front Matter....Pages 611-611
Effectiveness of Respiratory Hyperoxia, of Normobaric and of Hyperbaric Oxygen Atmospheres in Improving Tumor Oxygenation....Pages 613-619
Impact of Various Thermal Doses on the Oxygenation and Blood Flow in Malignant Tumors Upon Localized Hyperthermia....Pages 621-629
Front Matter....Pages 631-631
Measurement of Local Po 2 and Intracapillary Hemoglobin Oxygenation in Lung Tissue of Rabbits....Pages 633-641
Cessation of Capillary Blood Flow Induced by Localized Application of Carbon Dioxide....Pages 643-649
Hypoxic Reduction in Blood Flow Velocity in Pulmonary Arterioles and Capillaries....Pages 651-660
Retinal Oxygen Tension in Diabetic Dogs Following Insulin Infusion....Pages 661-670
Front Matter....Pages 631-631
A Mechanism for Oxygen Damage to the Immature Retinal Vasculature....Pages 671-687
Reactions of Carotid Baroreceptors to Anoxia and Ischaemia....Pages 689-701
Front Matter....Pages 703-703
O 2 Chemoreception of the Cat Carotid Body in vitro ....Pages 705-717
Local Variations of Oxygen Consumption Within Multicellular Spheroids Calculated from Measured Po 2 Profiles....Pages 719-728
Front Matter....Pages 729-729
The Fine Adjustment of Capillary Blood Flow Through Excitation of the Capillary Wall....Pages 731-737
Intermediate Size Filaments and Microfilaments in Frog Mesenteric Capillaries....Pages 739-746
Effect of Adrenaline on Capillary Diameter in the Frog Mesentery....Pages 747-753
Rhythmicity and Tension Development of Spontaneous Contracting Capillaries in the Mesentery of Frogs....Pages 755-759
Front Matter....Pages 761-761
Transcutaneous Po 2 During Exercise....Pages 763-774
Quantification of the Utilization of Reserve Oxygen Transport Capacity; Initial Studies in Critically Ill Patients....Pages 775-779
On a Generalized Bioenergetic Control Mechanism of Microcirculation with Different Effects in the Lung and the Other Parts of the Body....Pages 781-791
Oxygen Profiles and Structure of Penicillium Chrysogenum Pellets....Pages 793-799
Front Matter....Pages 801-801
Some Aspects of Signal Analysis Applied to Intracapillary Hemoglobin Spectra....Pages 803-810
Correlation Between Tissue Po 2 and Intracapillary Hb Spectra....Pages 811-819
Evaluation of Reflection Spectra of the Isolated Heart by Multicomponent Spectra Analysis in Comparison to other Evaluating Methods....Pages 821-830
Quantitative Analysis of Reflection Spectra of the Surface of the Guinea Pig Brain....Pages 831-839
Assessment of Brain Oxygenation: A Comparison Between an Oxygen Electrode and Near-Infrared Spectrophotometry....Pages 841-847
Cryogenic Microspectrophotometry....Pages 849-850
A Measuring Device to Determine a Universal Parameter for the Flow Characteristics of Blood: Measurement of the Yield Shear Stress in a Branched Capillary....Pages 851-857
Television Fluorescein-Angiography of the Retina with On-Line Measurement of the Dilution Curves....Pages 859-867
Front Matter....Pages 801-801
Micro, Surface, and Needle Oxygen Electrodes: Comparison of Physiological Relevance and Clinical Acceptance....Pages 869-875
An Improved Polarographic Multiwire Surface Po 2 Electrode, Particularly for Measurement of High Po 2 Values....Pages 877-886
Steady State Condition — What Does it Mean During Investigation of Oxygen Supply?....Pages 887-897
Evidence for Boundary Layer Effects Influencing the Sensitivity of Microencapsulated O 2 Fluorescence Indicator Molecules....Pages 899-905
A Correction Method for Ionic Strength-Independent Fluorescence Photometric pH Measurement....Pages 907-912
Influence of Enzyme Concentration and Thickness of the Enzyme Layer on the Calibration Curve of the Continuously Measuring Glucose Optode....Pages 913-921
Back Matter....Pages 923-942