Oxygen Transport to Tissue — II

Front Matter....Pages N1-xxiii
Front Matter....Pages 1-1
A Method for Simultaneous Measurements of Bioelectric Activity and Local Tissue PO 2 in the CNS....Pages 3-7
Oxygen Fields Induced by Recessed and Needle Oxygen Microelectrodes in Homogeneous Media....Pages 9-16
The Application of Histological Analysis for the Localization of Tissue PO 2 and Local Blood Flow with the Example of the Glomus Caroticum of the Rabbit (Oryctolagus Cuniculus)....Pages 17-23
A Method for Measuring Oxygen Uptake Rate Distributions Over the Surface Zone of Excised Tissues Using a 91-Cathode Electrode....Pages 25-32
Monitoring of PO 2 in Human Blood....Pages 33-40
A New Approach to the Experimental Measurement of Mean Tissue PO 2 ....Pages 41-46
Pyrene Butyric Acid: A Non-Invasive Probe for In Situ Intracellular Oxygen Concentration....Pages 47-54
Kryomicrophotometry as a Method for Analyzing the Intracapillary HbO 2 Saturation of Organs Under Different O 2 Supply Conditions....Pages 55-64
Quantitative Fluorescence Photometry with Biological Fluids and Gases....Pages 65-68
Control of Electrode Aging by a Periodic Anodization Technique....Pages 69-75
Front Matter....Pages 79-79
Effects of 2,3-Diphosphoglycerate on Functional Properties of Hemoglobin and on Glycolysis of Human Erythrocytes....Pages 81-88
The Effect of Red Cell 2,3-DPG Changes Induced by Diabetic Ketoacidosis on Parameters of the Oxygen Dissociation Curve in Man....Pages 89-95
The Influence of MgCl 2 on the O 2 -Hb-Binding Curve of Human Hemoglobin Under Intracellular Conditions....Pages 97-103
Oxygen Transport and Hemodynamics of Stroma-Free Hemoglobin Solutions....Pages 105-112
Oxygen Transport on Mount Everest: The Effects of Increased Hematocrit on Maximal O 2 Transport....Pages 113-119
Measurement of Oxygenation and Deoxygenation of a Single Red Cell of Chicken Embryo by Means of a Microphotometer....Pages 121-130
Front Matter....Pages 135-135
Cellular Control of Mitochondrial Respiration....Pages 137-144
Influence of Hemoglobin Oxygen Affinity on Oxidation Reduction State of Cytochrome aa 3 in Perfused Liver....Pages 145-150
Problems in Determination of Oxygen Dissociation of Avian Blood....Pages 151-158
Metabolic and Electron Microscopic Studies Post Mortem in Brain Mitochondria....Pages 159-164
Front Matter....Pages 135-135
Early Structural Changes in Mitochondria in Response to Acute Reductions in Capillary Flow....Pages 165-170
The Induction of Cytochrome P-450 by Hypoxia....Pages 171-175
Front Matter....Pages 181-181
Diffusion of Oxygen in Plasma and Blood....Pages 183-190
Facilitated Diffusion of Oxygen in Red Blood Cell Suspensions....Pages 191-198
Measurement of Diffusivity and Metabolic Rate of O 2 and CO 2 in Respiring Tissue....Pages 199-206
Facilitated Diffusion of CO and Oxygen in the Presence of Hemoglobin or Myoglobin....Pages 207-215
The Measurement of the Fraction of Oxygen Carried by Facilitated Diffusion....Pages 217-223
Measurement of Diffusion Parameters with Noble Metal Electrodes....Pages 225-228
Front Matter....Pages 231-231
A Generalized Advancing front Model Describing the Oxygen Transfer in Flowing Blood....Pages 233-240
A Theoretical Model of the Respiratory Function of Blood....Pages 241-249
Some Model Results on Hemoglobin Kinetics and Its Relationship to Oxygen Transport in Blood....Pages 251-259
The Mechanical Basis for Fick’s Law and Its Generalizations....Pages 261-265
A Stochastic Model for the Transport of Oxygen to Brain Tissue....Pages 267-277
Models for O 2 and CO 2 Transfer in Macroscopic Flow Channels and Their Physiological Implications....Pages 279-284
Front Matter....Pages 287-287
Correlation between the Redox State, Electrical Activity and Blood Flow in Cat Brain CORTEX During Hemorrhagic Shock....Pages 289-297
Cortical NADH, pO 2 , Electrical Activity and Arterial Blood Pressure Oscillations in Hypoxaemia....Pages 299-305
The Effect of Decapitation on the Oxidation-Reduction State of NADH and ECoG in the Brain of the Awake Rat....Pages 307-312
Cerebral Oxygen Supply in Brain Edema and During Ventriculo-Cisternal Perfusion....Pages 313-324
Tissue Responses to Hypoxia, Shock and Stroke....Pages 325-333
Cerebral Oxygenation in Arterial Hypoxia....Pages 335-342
Front Matter....Pages 287-287
Theoretical and Experimental Aspects of Brain Tissue Oxygenation Dynamics....Pages 343-354
Front Matter....Pages 359-359
Local Tissue Po 2 and Microflow of the Brain Cortex Under Varying Arterial Oxygen Pressure....Pages 361-367
An Analysis of Ion Distribution in Brain Following Anoxia....Pages 369-374
Comparison of Oxygen Tension in the Spinal Cord and Globus Pallidus During Hyperbaric Oxygen Exposure of Rats Under Pentobarbital Anesthesia....Pages 375-382
Autonomic and Pharmacological Control of Oxygen Autoregulation Mechanisms in Brain Tissue....Pages 383-389
Effects of So-Called “Cerebral Blood Flow Increasing” Drugs on Tissue-Oxygenation of the Brain....Pages 391-398
Front Matter....Pages 403-403
Oxygen Supply to the Open Rabbit Cornea....Pages 405-412
Studies on Retinal Oxygenation....Pages 413-416
A System for in Vivo Measurement of Oxygen in Intraocular Tissue....Pages 417-424
The O 2 Supply of the Isolated Cell-Free Perfused Rat Kidney....Pages 425-432
Effect of Vasopressors and Hemorrhage on Intrarenal Oxygenation....Pages 433-439
Renal Tissue Oxygenation During Hypoxic Hypoxia....Pages 441-447
Corneal Oxygen Supply Conditions....Pages 449-455
Front Matter....Pages 461-461
Cellular Oxygen Concentration....Pages 463-467
The Role of Carotid Chemoreceptors in the Regulation of Arterial Oxygen Transport under Hypoxia with and without Hypercapnia....Pages 469-476
Pulmonary Tissue Oxygen Requirement....Pages 477-482
Oxygen Delivery and Utilization in Hypoxic Dogs Made Acidemic and Alkalemic....Pages 483-489
Evidence Against Local Control of Intestinal Tissue Oxygenation by Myogenic Mechanisms....Pages 491-496
Effect of Ionizing Radiation on Liver Microcirculation and Oxygenation....Pages 497-503
A Factor in Longitudinal Tissue Gradients: Red Cell Carriage....Pages 505-510
Front Matter....Pages 461-461
Effects of Dopamine and Epinephrine on Intestinal Blood Flow and Oxygen Uptake....Pages 511-516
Front Matter....Pages 519-519
In Vivo Utilization of Oxygen and Glucose by Neoplastic Tissue....Pages 521-536
O 2 Supply Conditions in Tumor Tissue in Vivo....Pages 537-546
Pathophysiological Aspects of Glucose Uptake by the Tumor Tissue under Various Conditions of Oxygen and Glucose Supply....Pages 547-553
Solution of the Diffusion Field Equation of Substrate Concentration in the Intercapillary Region Considering the Decrease in Substrate Consumption in the Unsaturated Region of Cancer Cell Glycolysis and Respiration....Pages 555-562
Computation of Glucose and O 2 Concentration Distribution in the Intercapillary Region of Intact Tumor Tissue Considering the Decrease in Substrate Consumption in the Unsaturated Region of Cancer Cell Glycolysis and Respiration....Pages 563-570
Mesenchyme Theory on the Increase in Resistance Experienced During Repetition of Cancer Therapy Processes....Pages 571-575
Front Matter....Pages 579-579
Studies on the Ability of the Tumor Respiration in Vivo to Fulfill its Physiological Functions....Pages 581-586
Control Mechanisms of Oxygen and Glucose Utilization in Tumours....Pages 587-596
Oxygen Distribution in Tumours: Influence on Cell Proliferation and Implications for Tumour Therapy....Pages 597-603
Preliminary Observations of Oxygen Levels in Microcirculation of Tumors in C3H Mice....Pages 605-610
The Distribution of Oxygen Consumption Rates in Some Tissues before and after X-Irradiation....Pages 611-617
Front Matter....Pages 621-621
Mechanisms of Circulation Metabolism Coupling in Skeletal Muscle....Pages 623-630
Spontaneous Oscillations of PO 2 in Muscle Tissue....Pages 631-637
Tissue PO 2 , VO 2 , Venous PO 2 and Perfusion Pressure in Resting Dog Gracilis Muscle Perfused at Constant Flow....Pages 639-655
Effect of a Shift of the Oxygen Dissociation Curve on Myocardial Oxygenation at Hypoxia....Pages 657-662
Tissue Blood Flow and Oxygenation during Large Vessel Surgery....Pages 663-666
Mechanisms of Increased Tissue Oxygen Delivery Following Release of Arterial Occlusion in Canine Skeletal Muscle and Skin....Pages 667-674
Mean Myoglobin Oxygen Tension during Exercise at Maximal Oxygen Uptake....Pages 675-683
Oxygen Transport in Skeletal Muscle: Capillary Geometry in Longitudinal Section....Pages 685-692
Front Matter....Pages 621-621
The Measurement of Myocardial Microflow and Its Reaction to Hypoxia and Hypercapnia....Pages 693-698
Front Matter....Pages 703-703
Oxygen Uptake of the Guinea Pig at Decreased and Increased Maternal Placental Blood Flow....Pages 705-712
Development and Adaptation of Heart Mitochondrial Respiratory Chain Function in Fetus and in Newborn....Pages 713-719
Experimental and Theoretical Analysis of Oxygen Transport in Fetal Brain....Pages 721-730
Fetal and Placental O 2 Consumption and the Uptake of Different Metabolites in the Ruminant and Horse during Late Gestation....Pages 731-736
Continuous PO 2 and Heart Rate Recording in the Human Newborn....Pages 737-745
A Comparison of Transcutaneous and Arterial PO 2 in Sick Neonates....Pages 747-752
Effect of Umbilical Artery Catheters on Oxygen Supply to Extremities....Pages 753-757
Tissue Oxygen Available (O 2 a) as a Criterion for the Effectiveness of Continuous Positive Pressure Breathing (CPPB)....Pages 759-763
Back Matter....Pages 769-781