Oxygen/Nitrogen Radicals: Cell Injury and Disease

Front Matter....Pages i-1
Cyclic oxidation and reduction of protein methionine residues is an important antioxidant mechanism....Pages 3-9
Signal transduction by nitric oxide in cellular stress responses....Pages 11-18
Effects of antioxidants against atherosclerosis....Pages 19-25
Molecular pathology of dityrosine cross-links in proteins: Structural and functional analysis of four proteins....Pages 27-38
The role of nitric oxide in lung innate immunity: Modulation by surfactant protein-A....Pages 39-48
Redox signaling....Pages 49-62
Control of mitochondrial membrane potential and ROS formation by reversible phosphorylation of cytochrome c oxidase....Pages 63-70
Molecular mechanisms of nitrogen dioxide induced epithelial injury in the lung....Pages 71-80
Differential role of hydrogen peroxide in UV-induced signal transduction....Pages 81-90
Upregulation of phosphoinositide 3-kinase and protein kinase B in alveolar macrophages following ozone inhalation. Role of NF-кB and STAT-1 in ozone-induced nitric oxide production and toxicity....Pages 91-98
Phospholipase D/phosphatidic acid signal transduction: Role and physiological significance in lung....Pages 99-109
Role of mitogen-activated protein kinases (MAPK) in cell injury and proliferation by environmental particulates....Pages 111-118
Doxorubicin-induced apoptosis: Implications in cardiotoxicity....Pages 119-124
Interactions of copper with glycated proteins:Possible involvement in the etiology of diabetic neuropathy....Pages 125-133
Mechanisms of neutrophil-induced DNA damage in respiratory tract epithelial cells....Pages 135-142
Asbestos-induced alveolar epithelial cell apoptosis:Role of mitochondrial dysfunction caused by iron-derived free radicals....Pages 143-151
Involvement of hydrogen peroxide in asbestos-induced NFAT activation....Pages 153-160
NF-кB, a pivotal transcription factor in silica-induced diseases....Pages 161-168
Effect of inhaled crystalline silica in a rat model: Time course of pulmonary reactions....Pages 169-176
The role of AP-1, NF-кB and ROS/ NOS in skin carcinogenesis: The JB6 model is predictive....Pages 177-184
Reactive oxygen species in choline deficiency induced carcinogenesis and nitrone inhibition....Pages 185-193
Tumor necrosis factor-α gene promoter polymorphism in coal workers’ pneumoconiosis....Pages 195-203
Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion....Pages 205-209
Cytokine polymorphisms in silicosis and other pneumoconiosis....Pages 211-217
Endogenous regulation of the acute inflammatory response....Pages 219-224
Role of nitric oxide in liver ischemia and reperfusion injury....Pages 225-228
Oxidative stress and TNF-a induce histone Acetylation and NF-кB/AP-1 activation in Alveolar epithelial cells: Potential mechanism In gene transcription in lung inflammation....Pages 229-237
Heme oxygenase/carbon monoxide signaling path-ways: Regulation and functional significance....Pages 239-248
The Role of Oxidative Stress in Nickel and Chromate Genotoxicity....Pages 249-263
Arsenic carcinogenicity: Relevance of c-Src activation....Pages 265-275
Roles of ferritin and iron in ischemic preconditioning of the heart....Pages 277-282
Molecular mechanisms of Cr(VI)-induced carcinogenesis....Pages 283-292
Arsenic induces oxidative DNA damage in mammalian cells....Pages 293-300
Generation of reactive oxygen species in the enzymatic reduction of PbCrO 4 and related DNA damage....Pages 301-308
Soluble metals as well as the insoluble particle fraction are involved in cellular DNA damage induced by particulate matter....Pages 309-315
Nitroxides as antioxidants: Tempol protects against E09 cytotoxicity....Pages 317-326
Reversal of fluoride induced cell injury through elimination of fluoride and consumption of diet rich in essential nutrients and antioxidants....Pages 327-333
Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy....Pages 335-340
 In vivo imaging of free radicals: Applications from mouse to man....Pages 341-357
 In vivo bioassays of acute asbestosis and its correlation with ESR spectroscopy and imaging in redox status....Pages 359-367
On the application of 4-hydroxybenzoic acid as a trapping agent to study hydroxyl radical generation during cerebral ischemia and reperfusion....Pages 369-377
 In vivo detection of nitric oxide distribution in mice....Pages 379-385
 In vivo measurement of tumor redox environment using EPR spectroscopy....Pages 387-392
Back Matter....Pages 393-398
....Pages 399-406