Optimizing Treatment for Children in the Developing World

Front Matter....Pages i-xvii
Front Matter....Pages 1-1
Children Everywhere Deserve Evidence-Based and Accessible Treatment....Pages 3-11
Shifting Demographics and Clinical Pharmacy/Pharmacology Priorities....Pages 13-19
Access to Medicines – More Than Just Affordability....Pages 21-32
Challenges in Pediatric Oral Dosing....Pages 33-44
Therapeutic Research in Low-Income Countries: Studying Trial Communities....Pages 45-52
MicroResearch: Finding Sustainable Local Health Solutions in East Africa Through Small Local Research Studies....Pages 53-64
Medications in Pregnancy: Can We Treat the Mother While Protecting the Unborn?....Pages 65-70
Drugs and Breastfeeding: The Knowledge Gap....Pages 71-79
Falsified and Substandard Medicines....Pages 81-95
Front Matter....Pages 97-97
Regulatory Science for Paediatric Medicines in Low- and Middle-Income Countries....Pages 99-108
Enabling Equitable Access to Essential Medicines....Pages 109-116
Clinical Pharmacy and Pharmaceutical Care....Pages 117-125
Promoting Drug Development and Access: The Role of International Networks and Organizations....Pages 127-139
Front Matter....Pages 141-141
Standards of Research for Clinical Trials in Low- and Middle-Income Countries....Pages 143-158
Ethical Considerations in the Design of Pediatric Clinical Trials in Low- and Middle-Income Countries....Pages 159-174
Micronutrient Deficiencies: Impact on Therapeutic Outcomes....Pages 175-186
Clinical Pharmacology and the Individualized Approach to Treatment....Pages 187-201
Neglected Diseases: Drug Development for Chagas Disease as an Example....Pages 203-211
Health Economic Evaluation for Improving Child Health in Low- and Middle-Income Countries....Pages 213-224
Rational Use of Medicines (RUM) for Children in the Developing World: Current Status, Key Challenges and Potential Solutions....Pages 225-238
Front Matter....Pages 141-141
Perspective on the Role of the Pharmaceutical Industry....Pages 239-247
Front Matter....Pages 249-249
Optimizing Malaria Treatment in the Community....Pages 251-264
Critical Care for Children in Low- and Middle-Income Countries: Issues Barriers and Opportunities....Pages 265-278
Child and Adolescent Mental Health Disorders: Organization and Delivery of Care....Pages 279-289
Psychotropic Medications in Pregnancy....Pages 291-302
Child Development, Disability and Global Health: Opportunity and Responsibility....Pages 303-310
Hydroxyurea Therapy for Sickle Cell Disease in Low-Income Countries....Pages 311-318
Front Matter....Pages 319-319
Challenges in Drug Therapy of Children in Africa....Pages 321-323
Training Clinicians in Developing Countries on Rational Use of Medications in Children and Pregnant Women....Pages 325-327
Taking Medicines for Children Forward....Pages 329-332