Oncology: An Evidence-Based Approach

Front Matter....Pages 1-1
Evidence-Based Approach to Oncology....Pages 3-13
Principles of Chemotherapy....Pages 14-40
Principles of Radiation Oncology....Pages 41-57
Principles of Surgical Therapy in Oncology....Pages 58-72
Principles of Targeted and Biological Therapies....Pages 73-90
Biologic Principles of Hematopoietic Stem Cell Transplantation....Pages 91-105
Evaluation of Tumor Markers: An Evidence-Based Guide for Determination of Clinical Utility....Pages 106-111
Design and Analysis of Oncology Clinical Trials....Pages 112-126
Ethics of Clinical Oncology Research....Pages 127-142
Informatics Infrastructure for Evidence-Based Cancer Medicine....Pages 143-150
Economics of Cancer Care....Pages 151-160
Principles of Screening for Cancer....Pages 161-176
Patient Decision Making....Pages 177-183
Establishing an Interdisciplinary Oncology Team....Pages 184-193
Principles of Complementary and Alternative Medicine for Cancer....Pages 194-203
Front Matter....Pages 205-205
Fundamental Aspects of the Cell Cycle and Signal Transduction....Pages 207-213
Viral Carcinogenesis....Pages 214-232
Environmental Carcinogenesis....Pages 233-243
Cancer Metastasis....Pages 244-253
Tumor Immunology and Immunotherapy....Pages 254-268
Front Matter....Pages 205-205
Technologies in Molecular Biology: Diagnostic Applications....Pages 269-284
Front Matter....Pages 285-285
Cancer Epidemiology....Pages 287-300
Evidence-Based Cancer Prevention Research: A Multidisciplinary Perspective on Cancer Prevention Trials....Pages 301-316
Screening....Pages 317-340
Genetic Screening and Counseling for High-Risk Populations....Pages 341-357
Behavior Modification....Pages 358-366
Front Matter....Pages 367-367
Central Nervous System Imaging....Pages 369-380
Breast Imaging....Pages 381-391
Imaging of Thoracic Malignancies....Pages 392-412
Imaging of Gastrointestinal Stromal Tumor....Pages 413-424
Genitourinary Imaging....Pages 425-441
Musculoskeletal Imaging....Pages 442-448
Positron Emission Tomography and Cancer....Pages 449-483
Front Matter....Pages 485-485
Central Nervous System Tumors....Pages 487-505
Eye, Orbit, and Adnexal Structures....Pages 506-534
Head and Neck Cancer....Pages 535-551
Lung Cancer....Pages 552-628
Therapy for Malignant Pleural Mesothelioma....Pages 629-651
Mediastinum....Pages 652-670
Esophageal Cancer....Pages 671-686
Front Matter....Pages 485-485
Stomach....Pages 687-710
Colon, Rectal, and Anal Cancer Management....Pages 711-739
Adenocarcinoma and Other Small Intestinal Malignancies....Pages 740-751
Cancer of the Liver and Bile Ducts....Pages 752-770
An Evidence-Based Approach to the Management of Pancreatic Cancer....Pages 771-788
Renal Cell Cancer....Pages 789-812
Ureter, Bladder, Penis, and Urethra....Pages 813-832
Prostate Cancer....Pages 833-850
Testis Cancer....Pages 851-880
Cervix, Vulva, and Vagina....Pages 881-898
Gestational Trophoblastic Neoplasia....Pages 899-909
Ovarian Cancer....Pages 910-936
Uterine Malignancies....Pages 937-959
Evidence-Based Management of Breast Cancer....Pages 960-991
Thyroid and Parathyroid....Pages 992-1013
Tumors of the Endocrine System....Pages 1014-1033
Sarcomas of Bone....Pages 1034-1047
Soft Tissue Sarcoma....Pages 1048-1081
Cutaneous Melanoma....Pages 1082-1101
Nonmelanoma Cutaneous Malignancies....Pages 1102-1118
Front Matter....Pages 485-485
Cancer of Unknown Primary Site....Pages 1119-1132
Solid Tumors of Childhood....Pages 1133-1156
Front Matter....Pages 1158-1158
Acute Myeloid Leukemia and the Myelodysplastic Syndromes....Pages 1160-1181
Acute Lymphoblastic Leukemia....Pages 1182-1209
Chronic Lymphocytic Leukemia and Related Chronic Leukemias....Pages 1210-1228
Chronic Myeloid Leukemia....Pages 1229-1239
An Evidence-Based Approach to the Management of Hodgkin’s Lymphoma....Pages 1240-1255
The Non-Hodgkin’s Lymphomas....Pages 1256-1284
Multiple Myeloma....Pages 1285-1296
Front Matter....Pages 1298-1298
Superior Vena Cava Syndrome....Pages 1300-1307
Central Nervous System Emergencies....Pages 1308-1320
Metabolic Emergencies in Oncology....Pages 1321-1331
Surgical Emergencies....Pages 1332-1348
Oral Complications of Cancer Therapy....Pages 1349-1362
Alopecia and Cutaneous Complications of Chemotherapy....Pages 1363-1371
Infectious Complications of Cancer Therapy....Pages 1372-1409
Acute Toxicities of Therapy: Pulmonary Complications....Pages 1410-1419
Cardiac Complications....Pages 1420-1426
Neurologic Complications of Therapy....Pages 1427-1434
Acute Toxicities of Therapy: Urologic Complications....Pages 1435-1442
Front Matter....Pages 1298-1298
Issues in Vascular Access with Special Emphasis on the Cancer Patient....Pages 1443-1454
Management of Cancer Pain....Pages 1455-1481
Nausea and Vomiting in the Cancer Patient....Pages 1482-1496
Nutritional Support for the Cancer Patient....Pages 1497-1514
Paraneoplastic Syndromes....Pages 1515-1526
Malignant Effusions....Pages 1527-1534
Evidence-Based Use of Hematopoietic Growth Factors for Optimal Supportive Care of Patients with Cancer....Pages 1535-1544
Management of the Bone Marrow Transplant Patient....Pages 1545-1560
Management of Anxiety and Depression in Adult Cancer Patients: Toward an Evidence-Based Approach....Pages 1561-1588
Reproductive Complications and Sexual Dysfunction in the Cancer Patient....Pages 1589-1609
The Care of the Terminal Patient....Pages 1610-1620
Metastatic Cancer to the Central Nervous System....Pages 1621-1634
Metastatic Cancer to Lung....Pages 1635-1644
Surgical and Regional Therapy for Liver Metastases....Pages 1645-1663
Metastatic Cancer to Bone....Pages 1664-1688
Cancer in the Immunosuppressed Patient....Pages 1689-1716
Cancer in the Older Population....Pages 1717-1729
Chemotherapy in Patients with Organ Dysfunction....Pages 1730-1746
Management of the Pregnant Cancer Patient....Pages 1747-1759
Front Matter....Pages 1761-1761
Survivorship Research: Past, Present, and Future....Pages 1763-1777
Front Matter....Pages 1761-1761
Late Effects of Cancer Treatments....Pages 1778-1800
Medical and Psychosocial Issues in Childhood Cancer Survivors....Pages 1801-1813
Medical and Psychosocial Issues in Hodgkin’s Disease Survivors....Pages 1814-1824
Medical and Psychosocial Issues in Testicular Cancer Survivors....Pages 1825-1837
Medical and Psychosocial Issues in Gynecologic Cancer Survivors....Pages 1838-1845
Medical, Psychosocial, and Health-Related Quality of Life Issues in Breast Cancer Survivors....Pages 1846-1868
Medical and Psychosocial Issues in Prostate Cancer Survivors....Pages 1869-1880
Physical and Psychosocial Issues in Lung Cancer Survivors....Pages 1881-1900
Cancer Survivorship Issues in Colorectal Cancer....Pages 1901-1911
Medical and Psychosocial Issues in Transplant Survivors....Pages 1912-1938
Second Malignancies After Radiation Treatment and Chemotherapy for Primary Cancers....Pages 1939-1951
Psychosocial Rehabilitation in Cancer Care....Pages 1952-1964
Cancer Advocacy....Pages 1965-1968