Oncogenes in B-Cell Neoplasia: Workshop at the National Cancer Institute, National Institute of Health, Bethesda, MD, USA, March 5–7, 1984

Front Matter....Pages I-XIII
Introductory Remarks....Pages 1-5
Activated Oncogenes in Burkitt’s Lymphoma....Pages 6-14
Detection of an Adenovirus E1A-like Activity in Mammalian Cells....Pages 15-19
Does the Large T Protein of Polyoma Virus Regulate the Expression of the Cellular myc Gene?....Pages 20-25
Genome Structure and Host Range Restriction of the Lymphotropic Papovavirus (LPV): Identification of a Viral Lymphocyte Specific Enhancer Element....Pages 26-30
Tlym-I, a Stage Specific Transforming Gene Shares Homology with MHC I Region Genes....Pages 31-33
Structural and Functional Analysis of ras and Blym Oncogenes....Pages 34-36
Structural Organization of Mouse c-myb Locus and the Mechanism of its Rearrangement in ABPL-2 Tumor Line Induced by Pristane and Abelson Murine Leukemia Virus....Pages 37-40
Disruption and Activation of the c-myb Locus by M-MuLV Insertion in Plasmacytoid Lymphosarcomas Induced by Pristane and Abelson Viruses....Pages 41-46
Follicular Hyperplasia in the Prelymphomatous Avian Bursa: Relationship to the Incidence of B-Cell Lymphomas....Pages 47-55
Multiple Steps in the Transformation of Normal B Cells Towards Neoplasia....Pages 56-61
Transferrin Receptors Regulate Proliferation of Normal and Malignant B Cells....Pages 62-68
Cloned Neoplastic B Cells Release a Growth Factor Which Augments Lymphokine-Mediated Proliferation of Normal B Cells....Pages 69-71
The Action of an Lyb2.1-Specific Monoclonal Antibody in Soluble or Immobilized Form on Resting and Activated B Cells....Pages 72-76
T Cell Factors Regulating B Cell Activation and Differentiation....Pages 77-85
Interleukin 3 Dependent Retrovirus Induced Lymphomas: Loss of the Ability to Terminally Differentiate in Response to Differentiation Factors....Pages 86-91
Growth Regulation of a B-Cell Lymphoma via the Antigen Receptor....Pages 92-95
Interleukin-2 Receptors on Activated Malignant and Normal B-Cells....Pages 96-101
Immuno Affinity Purified Interleukin 2 (IL2) Induces B Cell Growth....Pages 102-103
Factors Affecting Normal and Malignant B Lymphocyte Precursors....Pages 104-108
Immunoglobulin Heavy Chain Switching in Cultured I.29 Murine B Lymphoma Cells: Commitment to an IgA or IgE Switch....Pages 109-116
The Regulation of c-myc by Growth Signals....Pages 117-126
Immune Regulation of the c-myc Oncogene in a Murine B Lymphoma....Pages 127-132
The Translocated c-myc Oncogene of Burkitt Lymphoma is Differentially Regulated in Lymphoblastoid vs Plasma Cells....Pages 133-145
Modes of c-myc Oncogene Activation in Murine Plasmacytomas....Pages 146-153
DNA Sequences Involved in the Rearrangement and Expression of the Murine c-myc Gene....Pages 154-160
Activation of the c-myc Oncogene in B and T Lymphoid Tumors....Pages 161-165
The c-myc Gene Paradox in Burkitt’s Lymphoma Chromosomal Translocation....Pages 166-171
Amplification, Expression and Rearrangement of c-myc and N-myc Oncogenes in Human Lung Cancer....Pages 172-175
Chromosomal Aberrations in Murine Plasmacytomas....Pages 178-182
Chromatin Structural Changes in the Putative Regulatory Region of c-myc Accompany the Translocation in a Burkitt Lymphoma....Pages 183-189
Aberrant Rearrangements at the Murine Light Chain Locus in Plasmacytomas....Pages 190-191
myc-Encoded Proteins of Chickens and Men....Pages 192-197
Properties of the myc-Gene Product: Nuclear Association, Inhibition of Transcription and Activation in Stimulated Lymphocytes....Pages 198-207
Introduction to Long-Term Cultures of Normal B Lymphocytes....Pages 208-209
Characteristics of Continuous in vitro Lines of BALB/c and NZB B Cells....Pages 210-216
Development of Cells of the B-Lymphocyte Lineage in Longterm Culture....Pages 217-223
Coexpression of Lyb-2 and Mac-1 by Murine Lymphomas and Subpopulations of Normal Spleen and Bone Marrow Cells....Pages 224-230
Ly-1 as a Differentiation Antigen on Normal and Neoplastic B Cells....Pages 231-236
Propagation of B Lymphocytes in Vitro....Pages 237-240
Identification of a Transforming Virus from a Lymphoma of a Mouse Infected with a Wild Mouse Retrovirus....Pages 241-249
Transformation Capacities of a Murine Retrovirus Encoding an Avian myc Oncogene....Pages 250-250
The CH Series of Murine B Cell Lymphomas: Identification of Cross-reactive Idiotypes and Restricted Antigen Specificities....Pages 251-257
Interaction of Acute Transforming Retroviruses with Murine Hematopoietic Cells....Pages 258-264
Monoclonal Antibody to Abelson Lymphoma Cells....Pages 265-268