Nutraceuticals : efficacy, safety and toxicity

Content: 
Front-matter,Copyright,Dedication,List of Contributors,IntroductionEntitled to full textSection I: Applications of Nutraceuticals in Common Diseases and DisordersChapter 1 - Nutraceuticals in CNS Diseases: Potential Mechanisms of Neuroprotection, Pages 3-13, Lucio G. Costa, Jacqueline Garrick, Pamela J. Roque, Claudia Pellacani
Chapter 2 - Prevention of Neurodegenerative Disorders by Nutraceuticals, Pages 15-28, Francesca Pistollato, Magdalini Sachana
Chapter 3 - Cognitive Effects of Nutraceuticals, Pages 29-48, Jason Pitt, Yiuka Leung
Chapter 4 - Nutraceuticals in Cardiovascular Diseases, Pages 49-59, Csaba K. Zoltani
Chapter 5 - Antiatherosclerotic Efficacy of Nutraceuticals, Pages 61-73, Alexander N. Orekhov, Ekaterina A. Ivanova
Chapter 6 - Nutraceuticals in Respiratory Disorders, Pages 75-86, Kavita Gulati, Nishant Rai, Sulekha Chaudhary, Arunabha Ray
Chapter 7 - Nutraceuticals in Hepatic Diseases, Pages 87-99, Sharon M. Gwaltney-Brant
Chapter 8 - Nutraceuticals in Renal Diseases, Pages 101-108, Sharon M. Gwaltney-Brant
Chapter 9 - Nutraceuticals in Gastrointestinal Disorders, Pages 109-122, Aryamitra Banerjee, Rajan Giri
Chapter 10 - Nutraceuticals in Reproductive and Developmental Disorders, Pages 123-134, Rajendra K. Singh
Chapter 11 - Nutraceuticals in Cancer Prevention, Pages 135-144, M. Waheed Roomi, Tatiana Kalinovsky, Matthias Rath, Aleksandra Niedzwiecki
Chapter 12 - Nutraceuticals in Glucose Balance and Diabetes, Pages 145-160, Ramesh C. Garg
Chapter 13 - Nutraceuticals in Arthritis, Pages 161-176
Chapter 14 - Nutraceuticals in Sports Activities and Fatigue, Pages 177-188, Nikolay Goncharov, Eugene Maevsky, Natalia Voitenko, Artem Novozhilov, Igor Kubasov, Richard Jenkins, Pavel Avdonin
Chapter 15 - Application of “Nano” Nutraceuticals in Medicine, Pages 189-192, Indu Javeri
Chapter 16 - Nutraceuticals as Adaptogens: Their Role in Health and Disease, Pages 193-205, Kavita Gulati, Rashmi Anand, Arunabha Ray
Chapter 17 - The Biology of Nutrients: Genetic and Molecular Principles*, Pages 209-225, Supratim Choudhuri, Ronald F. Chanderbhan
Chapter 18 - Genomic and Proteomic Mechanisms and Models in Toxicity and Safety Evaluation of Nutraceuticals, Pages 227-237, Beena M. Kadakkuzha, Xin-an Liu, Supriya Swarnkar, Youjun Chen
Chapter 19 - Adverse Reaction Prediction and Pharmacovigilance of Nutraceuticals: Examples of Computational and Statistical Analysis on Big Data, Pages 239-248, Kejian Wang
Chapter 20 - Gene Expression Profiling in Evaluating the Safety and Toxicity of Nutraceuticals*, Pages 249-262, Nan Mei, Jiekun Xuan, Tao Chen, Baitang Ning, Lei Guo
Chapter 21 - Target Identification and Polypharmacology of Nutraceuticals, Pages 263-286, György Dormán, Beáta Flachner, István Hajdú, Csaba D. András
Chapter 22 - Mechanistic Network Models in Safety and Toxicity Evaluation of Nutraceuticals, Pages 287-304, Ignacio Gonzalez-Suarez, Florian Martin, Julia Hoeng, Manuel C. Peitsch
Chapter 23 - Noninvasive In Vivo Optical Imaging Models for Safety and Toxicity Testing, Pages 305-317, Jeffrey D. Peterson
Chapter 24 - Flow Cytometry and Light Scattering Technique in Evaluation of Nutraceuticals, Pages 319-332, Igor Mindukshev, Igor Kudryavtsev, Maria Serebriakova, Andrey Trulioff, Stepan Gambaryan, Julia Sudnitsyna, Denis Khmelevskoy, Natalia Voitenko, Pavel Avdonin, Richard Jenkins, Nikolay Goncharov
Chapter 25 - Zebrafish Model for Safety and Toxicity Testing of Nutraceuticals, Pages 333-339, Wan-Ping Bian, De-Sheng Pei
Chapter 26 - Caenorhabditis elegans: A Model Organism for Nutraceutical Safety and Toxicity Evaluation, Pages 341-354, Reid E. Barnett, Denise C. Bailey, Holly E. Hatfield, Vanessa A. Fitsanakis
Chapter 27 - Alternative In Vitro Models for Safety and Toxicity Evaluation of Nutraceuticals, Pages 355-385, Gopala Krishna, Gopa Gopalakrishnan
Chapter 28 - Mitochondria as a Target for Safety and Toxicity Evaluation of Nutraceuticals, Pages 387-400, João S. Teodoro, Filipe V. Duarte, Anabela P. Rolo, Carlos M. Palmeira
Chapter 29 - Oxidative Stress and Excitotoxicity: Antioxidants from Nutraceuticals, Pages 401-413, Dejan Milatovic, Snjezana Zaja-Milatovic, Ramesh C. Gupta
Chapter 30 - Caffeine: An Evaluation of the Safety Database, Pages 417-434, Ashley Roberts
Chapter 31 - Curcumin, Pages 435-445, Indu Javeri, Naresh Chand
Chapter 32 - Quercetin, Pages 447-452, Muhammet Ay, Adhithiya Charli, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy
Chapter 33 - Resveratrol: Multiple Activities on the Biological Functionality of the Cell, Pages 453-464, Gianfranco Risuleo
Chapter 34 - Isoflavones: Toxicological Aspects and Efficacy, Pages 465-487, Harald L. Esch, Carolin Kleider, Anne Scheffler, Leane Lehmann
Chapter 35 - Anthocyanins, Pages 489-500, Britt Burton-Freeman, Amandeep Sandhu, Indika Edirisinghe
Chapter 36 - Melatonin: A Safe Nutraceutical and Clinical Agent, Pages 501-509, Edward H. Sharman, Stephen C. Bondy
Chapter 37 - Arginine and Citrulline as Nutraceuticals: Efficacy and Safety in Diseases, Pages 511-529, S.N. Kaore, Navinchandra M. Kaore
Chapter 38 - Astaxanthin: Health Benefits and Toxicity, Pages 531-539, Tetsuo Satoh
Chapter 39 - Thymoquinone, Pages 541-550, Bhanushree Gupta, Kallol K. Ghosh, Ramesh C. Gupta
Chapter 40 - Glucosinolates, Pages 551-554, Karyn L. Bischoff
Chapter 41 - Organosulfur Compounds as Nutraceuticals, Pages 555-568, Nikolay Goncharov, Alexander N. Orekhov, Natalia Voitenko, Anton Ukolov, Richard Jenkins, Pavel Avdonin
Chapter 42 - Spirulina, Pages 569-583, Dan Wan, Qinghua Wu, Kamil Kuča
Chapter 43 - Neem Extract, Pages 585-597, Dinesh Kumar, Anu Rahal, Jitendra K. Malik
Chapter 44 - Fenugreek: Multiple Health Benefits, Pages 599-617, Ramesh C. Garg
Chapter 45 - St. John’s Wort, Pages 619-631, Robert W. Coppock, Margitta Dziwenka
Chapter 46 - Green Tea Extract, Pages 633-652, Robert W. Coppock, Margitta Dziwenka
Chapter 47 - Green Coffee Bean, Pages 653-667, Satish K. Garg
Chapter 48 - Garcinia cambogia, Pages 669-680, Rajinder Raina, Dilip M. Mondhe, Jitendra K. Malik, Ramesh C. Gupta
Chapter 49 - Ginkgo biloba, Pages 681-691, Margitta Dziwenka, Robert W. Coppock
Chapter 50 - Chinese Ginseng, Pages 693-705, Mildred S. Yang, Mei Yi Wu
Chapter 51 - Shilajit, Pages 707-716, Shailesh K. Bhavsar, Aswin M. Thaker, Jitendra K. Malik
Chapter 52 - Ashwagandha: Multiple Health Benefits, Pages 717-733, Vijay K. Bharti, Jitendra K. Malik, Ramesh C. Gupta
Chapter 53 - Cannabis sativa and Hemp, Pages 735-754, Joshua A. Hartsel, Joshua Eades, Brian Hickory, Alexandros Makriyannis
Chapter 54 - Prebiotics: Safety and Toxicity Considerations, Pages 757-775, Arturo Anadón, María Rosa Martínez-Larrañaga, Irma Ares, María Aránzazu Martínez
Chapter 55 - Probiotics: Safety and Toxicity Considerations, Pages 777-798, Arturo Anadón, María Rosa Martínez-Larrañaga, Irma Ares, María Aránzazu Martínez
Chapter 56 - Probiotics: Preclinical Testing for Verification of Their Gastrointestinal Effectiveness, Pages 799-810, Martin Kunes, Jaroslav Kvetina
Chapter 57 - Synbiotics: Safety and Toxicity Considerations, Pages 811-822, Jitendra K. Malik, Abul H. Ahmad, Starling Kalpana, Atul Prakash, Ramesh C. Gupta
Chapter 58 - Toxic Contamination of Nutraceuticals and Food Ingredients, Pages 825-837, Fernando Gil, Antonio F. Hernández, M. Concepción Martín-Domingo
Chapter 59 - Nutraceuticals and Adverse Outcome Pathways, Pages 839-853, Antonio F. Hernández, Fernando Gil
Chapter 60 - Interactions between Nutraceuticals/Nutrients and Therapeutic Drugs, Pages 855-874, Arturo Anadón, María Rosa Martínez-Larrañaga, Irma Ares, María Aránzazu Martínez
Chapter 61 - Interactions between Chinese Nutraceuticals and Western Medicines, Pages 875-882, Noel Chan, Sandy Li, Evette Perez
Chapter 62 - Assessment of Genotoxic Effects of Selected Herbal Dietary Supplements*, Pages 883-892, Zhuhong Zhang, Nan Mei, Si Chen, Lei Guo, Xiaoqing Guo
Chapter 63 - Evaluation and Regulation of Food Supplements: European Perspective, Pages 895-923, Arturo Anadón, María Rosa Martínez-Larrañaga, Irma Ares, María Aránzazu Martínez
Chapter 64 - Seed to Patient in Clinically Proven Natural Medicines*, Pages 925-931, Dilip Ghosh
Chapter 65 - Regulatory Aspects of Nutraceuticals: Japanese Perspective, Pages 933-940, Keizo Umegaki
Chapter 66 - Regulatory Aspects of Nutraceuticals: An Indian Perspective, Pages 941-946, Arunabha Ray, Jagdish Joshi, Kavita Gulati
Chapter 67 - Regulatory Aspects of Nutraceuticals: Chinese Perspective, Pages 947-957, Mildred S. Yang
Chapter 68 - Regulatory Aspects of Nutraceuticals: Russian Perspective, Pages 959-970, Victor A. Tutelyan, Alexey S. Petrenko, Elena A. Smirnova, Boris P. Sukhanov, Anatoliy V. Kutyshenko
Chapter 69 - Nutraceuticals: Turkish Perspective, Pages 971-981, Begum Yurdakok Dikmen, Ayhan Filazi
Index, Pages 983-1022