Nitrosoureas. Current Status and New Developments

Content: 
Front Matter, Page iii
Copyright, Page iv
CONTRIBUTORS, Pages xiii-xviii
PREFACE, Page xix
Chapter 1 - THE DEVELOPMENT OF THE NITROSOUREAS: A STUDY IN CONGENER SYNTHESIS, Pages 3-8, John A. Montgomery
Chapter 2 - COMBINATION CHEMOTHERAPY WITH NITROSOUREAS PLUS OTHER ANTICANCER DRUGS AGAINST ANIMAL TUMORS, Pages 9-26, Frank M. Schabel Jr., W. Russell Laster Jr., Mary W. Trader, Thomas H. Corbett, Daniel P. Griswold Jr.
Chapter 3 - EORTC STUDIES WITH NOVEL NITROSOUREAS, Pages 27-42, F. Spreafico, S. Filippeschi, P. Falautano, G. Eisenbrand, H.H. Fiebig, M. Habs, V. Zeller, M. Berger, D. Schmähl, L.M. Van Putten, T. Smink, E. Csányi, S. Somfai-Relle
Chapter 4 - CHEMICAL DECOMPOSITION OF CHLOROETHYLNITROSOUREAS, Pages 43-49, Michael Colvin, Robert Brundrett
Chapter 5 - METABOLISM OF NITROSOUREAS, Pages 51-67, Donald J. Reed
Chapter 6 - DNA CROSSLINKING AND THE ORIGIN OF SENSITIVITY TO CHLOROETHYLNITROSOUREAS, Pages 69-83, Kurt W. Kohn, Leonard C. Erickson, Guy Laurent, Jonathan Ducore, Nancy Sharkey, Regina A. Ewig
Chapter 7 - MODIFICATION OF DNA AND RNA BASES, Pages 85-94, David B. Ludlum, William P. Tong
Chapter 8 - CARBAMOYLATING ACTIVITY OF NITROSOUREAS, Pages 95-105, Herbert E. Kann Jr.
Chapter 9 - CHROMATIN AND ASSOCIATED NUCLEAR COMPONENTS AS POTENTIAL DRUG TARGETS, Pages 107-121, Kenneth D. Tew
Chapter 10 - ADP-RIBOSYLATION AND DNA REPAIR AS INDUCED BY NITROSOUREAS, Pages 123-142, Mark Smulson, Tauseef Butt, Swaroop Sudhakar, Don Jump, Nancy Nolan
Chapter 11 - SUBACUTE AND CHRONIC TOXICITIES ASSOCIATED WITH NITROSOUREA THERAPY, Pages 145-154, John S. Macdonald, Raymond B. Weiss, Donald Poster, Luz Hammershaimb
Chapter 12 - THE TOXICITY OF HIGH-DOSE BCNU WITH AUTOLOGOUS MARROW SUPPORT, Pages 155-169, Tak Takvorian, Fred Hochberg, George Canellos, Leroy Parker, Nicholas Zervas, Emil Frei
Chapter 13 - CLINICAL PHARMACOLOGY OF THE NITROSOUREAS, Pages 171-180, Victor A. Levin
Chapter 14 - NITROSOUREAS IN THE THERAPY OF HODGKIN'S DISEASE, Pages 181-197, Arlan J. Gottlieb, Clara D. Bloomfield, Arvin S. Glicksman, Nis I. Nissen, M. Robert Cooper, Thomas F. Pajak, James F. Holland
Chapter 15 - HODGKIN'S DISEASE AND MALIGNANT LYMPHOMAS, Pages 199-208, Richard A. Gams, John R. Durant
Chapter 16 - CCNU IN COMBINATION CHEMOTHERAPY FOR SMALL-CELL LUNG CANCER, Pages 209-220, Robert L. Comis, Sandra J. Ginsberg, Thomas F. Pajak, L. Herbert Maurer
Chapter 17 - POCC VERSUS POCC/VAM THERAPY FOR SMALL-CELL ANAPLASTIC (OAT CELL) LUNG CANCER, Pages 221-231, Branimir Ivan Sikic, John R. Daniels, Linda Chak, Michael Alexander, Marsha Kohler, Stephen K. Carter
Chapter 18 - NITROSOUREA-CONTAINING COMBINATIONS IN SMALL-CELL LUNG CANCER, Pages 233-244, Paul A. Bunn Jr.
Chapter 19 - NITROSOUREA-CONTAINING CHEMOTHERAPY REGIMENS IN THE TREATMENT OF NON-SMALL-CELL LUNG CANCER, Pages 245-258, Martin H. Cohen
Chapter 20 - CHEMOTHERAPY OF RECURRENT BRAIN TUMORS, Pages 259-268, Victor A. Levin
Chapter 21 - LIPID-SOLUBLE NITROSOUREAS IN THE MANAGEMENT OF CHILDREN WITH PRIMARY AND RECURRENT BRAIN TUMORS, Pages 269-276, Jeffrey G. Rosenstock
Chapter 22 - ADJUVANT THERAPY OF BRAIN TUMORS WITH NITROSOUREAS, Pages 277-284, Michael E. Walker
Chapter 23 - CLINICAL USE OF NITROSOUREAS IN GASTROINTESTINAL CANCER, Pages 285-291, Paul V. Woolley III
Chapter 24 - A RANDOMIZED COMPARATIVE TRIAL IN COLORECTAL CANCER, Pages 293-299, Joan C. D'Aoust, Archie W. Prestayko, Brian F. Issell
Chapter 25 - CLINICAL USE OF NITROSOUREAS IN PATIENTS WITH MALIGNANT MELANOMA: A REVIEW, Pages 301-312, Muhyi Al-Sarraf
Chapter 26 - NITROSOUREAS IN THE TREATMENT OF MULTIPLE MYELOMA, Pages 313-324, O. Ross McIntyre, Thomas Pajak, Louis Leone, Robert Kyle, Gibbons G. Corwell, John Harley, Shaul Kochwa, Babette B. Weksler, Linda P. Glowienka
Chapter 27 - CLINICAL TRIALS OF NITROSOUREAS IN METASTATIC SARCOMAS, Pages 325-336, Saul E. Rivkin
Chapter 28 - HIGH-DOSE NITROSOUREA (BCNU) AND AUTOLOGOUS BONE MARROW TRANSPLANTATION: A PHASE I STUDY, Pages 337-341, Geoffrey P. Herzig, Gordon L. Phillips, Roger H. Herzig, Joseph W. Fay, R.L. Weiner, Steve N. Wolff, Hillard M. Lazarus
Chapter 29 - AMPHOTERICIN B: INTERACTIONS WITH NITROSOUREAS AND OTHER ANTINEOPLASTIC DRUGS, Pages 343-360, Cary A. Presant, Frederick Valeriote, Richard Proffitt, Gerald Metter
Chapter 30 - ACTIVITY OF NITROSOUREAS ON HUMAN TUMORS IN VITRO, Pages 361-365, Brian F. Issell, Claude Tihon, M. Elaine Curry
Chapter 31 - STREPTOZOTOCIN, Pages 367-377, Patrick J. Byrne, Philip S. Schein
Chapter 32 - PHASE I AND II STUDIES OF PCNU, Pages 379-385, Michael A. Friedman
Chapter 33 - CHLOROZOTOCIN: CLINICAL TRIALS, Pages 387-398, Daniel F. Hoth, Luz Duque-Hammershaimb
Chapter 34 - CURRENT STATUS OF NITROSOUREAS UNDER DEVELOPMENT IN JAPAN, Pages 399-409, Makoto Ogawa
Chapter 35 - DESIGN OF CLINICAL TRIALS WITH NITROSOUREA, Pages 411-416, Stephen K. Carter