Nitric Oxide: Biochemistry, Molecular Biology, and Therapeutic Implications

Content: 
Serial Editors
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Edited by
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Copyright page
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Contributors
Pages xix-xxiv

Chemistry of Nitric Oxide: Biologically Relevant Aspects Original Research Article
Pages 1-15
Jon M. Fukuto

Reactions between Nitric Oxide, Superoxide, and Peroxynitrite: Footprints of Peroxynitrite in Vivo Original Research Article
Pages 17-43
John P. Crow, Joseph S. Beckman

Oxygen Radical-Nitric Oxide Reactions in Vascular Diseases Original Research Article
Pages 45-69
Bruce A. Freeman, C. Roger White, Hector Gutierrez, Andrés Paler-Martínez, Margaret M. Tarpey, Homero Rubbo

Nitric Oxide Synthases: Gene Structure and Regulation Original Research Article
Pages 71-90
Yang Wang, Philip A. Marsden

Transcription of the Human Neuronal Nitric Oxide Synthase Gene in the Central Nervous System is Mediated by Multiple Promoters Original Research Article
Pages 91-112
Anthony P. Young, Ferid Murad, Harald Vaessin, Jinling Xie, Terrie K. Rife

Regulation of the Expression of the Inducible Isoform of Nitric Oxide Synthase Original Research Article
Pages 113-153
Csaba Szabó, Christoph Thiemermann

Regulation and Function of Inducible Nitric Oxide Synthase during Sepsis and Acute Inflammation Original Research Article
Pages 155-170
James M. Wong, Timothy R. Billiar

Expression and Expressional Control of Nitric Oxide Synthases in Various Cell Types Original Research Article
Pages 171-186
Ulrich Förstermann, Hartmut Kleinert, Ingolf Gath, Petra Schwarz, Ellen I. Closs, Nae J. Dun

Control and Consequences of Endothelial Nitric Oxide Formation Original Research Article
Pages 187-206
Ingrid Fleming, Rudi Busse

Control of Electron Transfer in Neuronal Nitric Oxide Synthase by Calmodulin, Substrate, Substrate Analogs, and Nitric Oxide Original Research Article
Pages 207-213
Dennis J. Stuehr, Husam M. Abu-Soud, Denis L. Rousseau, Paul L. Feldman, Jianling Wang

Negative Modulation of Nitric Oxide Synthase by Nitric Oxide and Nitroso Compounds Original Research Article
Pages 215-234
Jeanette M. Griscavage, Adrian J. Hobbs, Louis J. Ignarro

Regulation of Nitric Oxide Synthase: Role of Oxygen Radicals and Cations in Nitric Oxide Formation Original Research Article
Pages 235-250
Chandra K. Mittal, Chander S. Mehta

Why Tetrahydrobiopterin? Original Research Article
Pages 251-261
Bernd Mayer, Ernst R. Werner

Nitric Oxide and cGMP Signaling Original Research Article
Pages 263-275
Lee J. McDonald, Ferid Murad

Nitric Oxide and Intracellular Heme Original Research Article
Pages 277-291
Young-Myeong Kim, Hector A. Bergonia, Claudia Müller, Bruce R. Pitt, W. David Watkins, Jack R. Lancaster Jr.

High-Level Expression of Biologically Active Soluble Guanylate Cyclase Using the Baculovirus System is Strongly Heme-Dependent Original Research Article
Pages 293-303
Wolfgang A. Buechler, Sujay Singh, Janet Aktas, Stefan Müller, Ferid Murad, Rupert Gerzer

cGMP Signaling through cAMP- and cGMP-Dependent Protein Kinases Original Research Article
Pages 305-322
Thomas M. Lincoln, Padmini Komalavilas, Nancy J. Boerth, Lee Ann MacMillan-Crow, Trudy L. Cornwell

Physiological and Toxicological Actions of Nitric Oxide in the Central Nervous System Original Research Article
Pages 323-342
Valina L. Dawson, Ted M. Dawson

S-Nitrosothiols: Chemistry, Biochemistry, and Biological Actions Original Research Article
Pages 343-349
Gilbert R. Upchurch Jr., George N. Welch, Joseph Loscalzo

Glyceraldehyde-3-phosphate Dehydrogenase: A Target for Nitric Oxide Signaling Original Research Article
Pages 351-360
Bernhard Brüne, Eduardo G. Lapetina

Nitric Oxide Donors: Biochemical Pharmacology and Therapeutics Original Research Article
Pages 361-381
John Anthony Bauer, Brian P. Booth, Ho-Leung Fung

Nitric Oxide Donors: A Continuing Opportunity in Drug Design Original Research Article
Pages 383-398
Stephen R. Hanson, Thomas C. Hutsell, Larry K. Keefer, Daniel L. Mooradian, Daniel J. Smith

Nitric Oxide and Peripheral Adrenergic Neuromodulation Original Research Article
Pages 399-413
Roberto Levi, Kwan Ha Park, Michiaki Imamura, Nahid Seyedi, Harry M. Lander

A Study on Tumor Necrosis Factor, Tumor Necrosis Factor Receptors, and Nitric Oxide in Human Fetal Glial Cultures Original Research Article
Pages 415-438
Barbara A. St. Pierre, Douglas A. Granger, Joyce L. Wong, Jean E. Merrill

Inhaled Nitric Oxide, Clinical Rationale and Applications Original Research Article
Pages 439-456
Claes G. Frostell, Warren M. Zapol

Inhaled Nitric Oxide Therapy of Pulmonary Hypertension and Respiratory Failure in Premature and Term Neonates Original Research Article
Pages 457-474
Steven H. Abman, John P. Kinsella

Clinical Applications of Inhaled Nitric Oxide in Children with Pulmonary Hypertension Original Research Article
Pages 475-504
David L. Wessel, Ian Adatia

Index
Pages 505-516