New Insights into Cell and Membrane Transport Processes

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Molecular Properties of Voltage-Sensitive Sodium Channels....Pages 3-20
Front Matter....Pages 21-21
Studies of a Biological Energy Transducer....Pages 23-38
The Erythrocyte Anion-Exchange Protein....Pages 39-59
The Lysosomal Proton Pump....Pages 61-74
Ion Pumps, Ion Pathways, Ion Sites....Pages 75-95
Front Matter....Pages 97-97
Shifts between Modes of Calcium Channel Gating as a Basis for Pharmacological Modulation of Calcium Influx in Cardiac, Neuronal, and Smooth-Muscle-Derived Cells....Pages 99-124
Chemical Pharmacology of Ca 2+ Channel Ligands....Pages 125-143
Information Flow in the Calcium Messenger System....Pages 145-174
Neutrophil Activation, Polyphosphoinositide Hydrolysis, and the Guanine Nucleotide Regulatory Proteins....Pages 175-198
Front Matter....Pages 199-199
Agonist-Dependent Phosphoinositide Metabolism....Pages 201-216
Hormone-Induced Inositol Lipid Breakdown and Calcium-Mediated Cellular Responses in Liver....Pages 217-247
Comparison of the Na + Pump and the Ouabain-Resistant K + Transport System with Other Metal Ion Transport ATPases....Pages 249-259
Current Concepts of Tumor Promotion by Phorbol Esters and Related Compounds....Pages 261-274
Front Matter....Pages 275-275
Intracellular Protein Topogenesis....Pages 277-283
Analysis of Epithelial Cell Surface Polarity Development with Monoclonal Antibodies....Pages 285-304
Frequency and Time Domain Analysis of Epithelial Transport Regulation....Pages 305-326
The Epithelial Sodium Channel....Pages 327-344
Front Matter....Pages 345-345
Uptake and Intracellular Processing of Cell Surface Receptors....Pages 347-360
Sorting in the Prelysosomal Compartment (CURL)....Pages 361-375
Mechanisms of Molecular Sorting in Endosomes....Pages 377-402
Front Matter....Pages 345-345
Transport of Protein Toxins Across Cell Membranes....Pages 403-423
Back Matter....Pages 425-434