New Horizons in Allergy Immunotherapy

Front Matter....Pages i-xiv
Food Allergy in Atopic Dogs....Pages 1-7
Mechanisms of Allergic Bronchoconstriction in the Rat✲....Pages 9-15
The Role of Nebulized IFN-γ in the Modulation of Allergic Responses....Pages 17-23
Murine Animal Models to Study the Central Role of T Cells in Immediate-Type Hyersensitivity Responses....Pages 25-32
Glutathione S-Transferase Induces Murine Dermatitis that Resembles Human Allergic Dermatitis....Pages 33-37
Effects of rIL-12 Administration on an Antigen Specific Immune Response....Pages 39-41
Mapping the Genes for IgE Production and Allergy....Pages 43-53
Genetic Factors in Asthma....Pages 55-60
Regulation of Interleukin-12 Signalling During T Helper Phenotype Development....Pages 61-73
Responsiveness to the Major Pollen Allergen of Parietaria Officinalis is Associated with Defined HLA-DRB1* Alleles in Italian and Spanish Allergic Patients....Pages 75-79
HLA-DR3 is Associated with the IgE Immune Responsiveness to a Recombinant Allergen from Blomia tropicalis (BT)....Pages 81-83
Recombinant Allergens for Immunotherapy....Pages 85-93
Structural and Antigenic Studies of Cockroach Allergens and Their Relevance to Asthma....Pages 95-101
PJUFO: a Phagemid for Display of cDNA Libraries on Phage Surface Suitable for Selective Isolation of Clones Expressing Allergens....Pages 103-110
Automated Serology with Recombinant Allergens....Pages 111-116
Biological and Immunological Importance of BET v 1 Isoforms....Pages 117-126
Modulation of IgE-Binding Properties of Tree Pollen Allergens by Site-Directed Mutagenesis....Pages 127-135
Advantages and Disadvantages of Recombinant Allergens and Peptides for Specific Immunotherapy....Pages 137-140
T Cell Epitopes of Phl p 1, Major Pollen Allergen of Timothy Grass (Phleum pratense)....Pages 141-146
Recombinant Expression and Epitope Mapping of Grass Pollen Allergens....Pages 147-155
Molecular Characterization of Alternaria Alternata and Cladosporium Herbarum Allergens....Pages 157-161
Production of Recombinant Allergens and their Application for Immunotherapy....Pages 163-171
Use of Recombinant Group 5 Allergens to Investigate IgE-Mediated Sensitization to Blomia Tropicalis and Dermatophagoides Pteronyssinus....Pages 173-176
Dual Effects of Allergen-Mpeg Conjugates....Pages 177-184
Recombinant Allergens....Pages 185-196
Production of a Recombinant Protein From Alternaria Containing the Reported N-Terminal of the ALT A1 Allergen....Pages 197-203
Isolation of a CDNA Clone Encoding a Putative Alternaria alternata Alt a I Subunit....Pages 205-212
Peanut Hypersensitivity....Pages 213-216
Human T Cell Clones and Cell Lines Specific to Ovomucoid Recognize Different Domains and Consistently Express IL-5....Pages 217-217
Isolation and Cloning of Bet v 1-Homologous Food Allergens from Celeriac (Api gl) and Apple (Mal dl)....Pages 219-224
IGE and Monoclonal Antibody Reactivities to the Major Shrimp Allergen Pen a 1 (Tropomyosin) and Vertebrate Tropomyosins....Pages 225-230
Immunomodulation with T Cell Reactive Peptides....Pages 231-240
Molecular Cloning and Immunological Characterization of The Group 7 Allergens of House Dust Mites....Pages 241-242
Epitope Structure of Recombinant Isoallergens of Bet v 1....Pages 243-249
Characterisation of Recombinant Isoforms of Birch Pollen Allergen Bet v 1....Pages 251-254
LOL pII Allergen....Pages 255-260
Characterization of Group 1 Allergens from Eleven Grass Species....Pages 261-265
A Major Allergen Involved in IgE Mediated Cockroach Hypersensitivity is a 90 kD Protein with Multiple IgE Binding Domains....Pages 267-268
Molecular Characterization Of Hor v 9....Pages 269-277
Cytokine and Drug Modulation of TNFα in Mast Cells....Pages 279-285
Synthesis and Storage of Regulatory Cytokines In Human Eosinophils....Pages 287-294
Allergen Dose Dependent Cytokine Production Regulates Specific Ige And Igg Antibody Production....Pages 295-303
The Role of Accessory Cell Products in the Regulation of T Cell Cytokine Production....Pages 305-308
 In vivo Direction of CD4 T Cells to TH1 and TH2-Like Patterns of Cytokine Synthesis....Pages 309-316
Controversial Issues and Possible Answers on the Antigen-Specific Regulation of the IgE Antibody Response....Pages 317-325
In Situ Detection of Cytokines in Allergic Inflammation....Pages 327-335
Is Vaccination Against IgE Possible?....Pages 337-342
Role of Interleukin-4 in the Development of Allergic Airway Inflammation and Airway Hyperresponsiveness....Pages 343-347
The Roles Of CD40 And CD23 In IgE Regulation....Pages 349-354
Absence of Mutations in the 6Th Exon of FcεRI-β....Pages 355-358
Role of Type 2 T Helper Cells (TH2) in Allergic Disorders....Pages 359-363
Diversity of Human T Cell Receptor Sequences of T Cell Clones with Specificity for Bet v 1 Peptide/MHC II Complexes....Pages 365-374
Identification of Differentially Expressed Genes in CD19+ve B Lymphocytes in Allergic Asthma....Pages 375-380
Non Random Usage of T Cell Receptor α Gene Expression in Atopy Using Anchored PCR....Pages 381-389
Reduction of IgE Antibody Binding to rDer p 2 Variants Generated by Site-Directed Mutagenesis....Pages 391-394
Expression of the House Dust Mite Allergen Der p2 And Mutants In The Baker’s Yeast Saccharomyces cerevisiae ....Pages 395-398
The Function of Allergens May Determine Allergenicity....Pages 399-402
Differential Gene Expression for Interleukin-13 and Other Cytokines in the Skin of Atopic Dermatitis Patients and Healthy Subjects....Pages 403-404
Peptide Induced Anergy of Human Allergen-Specific T Cells....Pages 405-410
Natural And Recombinant ANTI-IgE Autoantibodies....Pages 411-416
Modulation of Anti-Allergen Immune Responses by Allergen-Antibody Complexes....Pages 417-424
Characterization of Allergenic Determinants on the C-Terminal Region of the r-Lol p 1....Pages 425-429
Anti-Idiotypic Antibodies in the Treatment of Allergies....Pages 431-437
Enhanced Production and Gene Expression of IL-5 in Bronchial Asthma....Pages 439-450
Peptide Mediated Regulation of Allergen Specific Immune Responses....Pages 451-456
Clinical Experience with Treatment of Allergies with T Cell Epitope Containing Peptides....Pages 457-461
Clinical Use of Recombinant Allergens and Epitopes....Pages 463-469
Diagnostic and Therapeutic Use of Recombinant Allergens....Pages 471-474
Back Matter....Pages 475-480