New Frontiers in Cytology: Modern Aspects of Research and Practice

Front Matter....Pages I-XXX
Front Matter....Pages 1-1
Cytology in Germany....Pages 3-9
Front Matter....Pages 11-11
In Situ Hybridization: An Overview....Pages 13-21
In Situ Hybridization: Its Use as a Tool in Pathology Laboratories....Pages 22-26
Correlations of Malignancy in Cultured Cells....Pages 27-31
Cytological Analysis of Functional Alterations in Granulocytes....Pages 32-36
Perspectives of Cytogenetic Analysis of Human Solid Tumors....Pages 37-40
Relationships Between Morphological Variants and Cytogenetic Findings in Acute Promyelocytic Leukaemia....Pages 41-44
Cytogenetic, Molecular, Immunologic, and Ultrastructural Study on an Established Cell Line of a Stage III Neuroblastoma....Pages 45-49
Kaposi’s Sarcoma: A Cytogenetic Study....Pages 50-52
Front Matter....Pages 53-53
Human Papillomaviruses as an Essential Factor for the Development of Cervical Cancer....Pages 55-62
HPV Infection of the Cervix Uteri: Prevalence and Age Distribution of a Sexually Transmissible Disease in a Cancer Screening Program....Pages 63-70
Conventional Cytology is Insensitive for the Detection of Genital HPV Infection....Pages 71-77
Alteration in Cell Morphology of a Human Neuroblastoma Line Under the Influence of Persistent Viral Infection....Pages 78-83
Front Matter....Pages 85-85
Introduction....Pages 87-89
DNA Measurement: Its Value for Diagnosis and Prognosis....Pages 90-94
DNA Flow Cytometry in Diagnostic Cytopathology: Methodologic Considerations and Current State of Clinical Applications....Pages 95-103
Flow Cytometry of DNA in Colorectal Adenomas and Adenocarcinomas....Pages 104-107
Sense and Nonsense of Cytomorphometry and Cytophotometry in Predicting Survival....Pages 108-129
Prognostic Validity of the DNA Malignancy Grade in Breast Cancer....Pages 130-134
Correlations of Cytomorphology, Hormone-Receptor Status, and Age in Patients with Breast Carcinoma....Pages 135-139
Front Matter....Pages 85-85
Quantitative Ultraviolet Microscopy....Pages 140-148
Front Matter....Pages 149-149
Immunocytochemistry in Cytology....Pages 151-158
Monoclonal Antibodies in Diagnostic Cytopathology....Pages 159-165
The Cytoskeleton: Diagnostic Possibilities and Limitations....Pages 166-177
Intermediate Filament Typing vs. Electron Microscopy in the Diagnosis of Major Tumor Types in Fine Needle Aspirates....Pages 178-191
Application of Immunocytochemical Methods to Cytological Specimens for Differential Diagnosis of Malignant Tumors....Pages 192-195
Front Matter....Pages 197-197
Tumour Typing in Fine-Needle Aspiration Biopsies by Immunocytochemistry....Pages 199-205
Immunocytochemical Determination of the Proliferation Fraction in Fine-Needle Aspiration Smears of Breast Tumors and Their Metastases....Pages 206-211
Growth Fraction as Determined in Cytologic Specimens of Breast Carcinomas: A Study with the Monoclonal Antibody Ki-67....Pages 212-215
Immunocytochemical Detection of Estrogen Receptors in Fine-Needle Aspirates of Breast Cancer....Pages 216-220
Front Matter....Pages 221-221
Immunocytochemical Differentiation of Lymphocytic Effusions....Pages 223-225
Immunocytochemistry: Methods and Applications....Pages 226-232
Improvement of Immunocytochemical Diagnosis of Neoplastic Effusions by Short-Term Culture of the Fluid: A Case Report....Pages 233-236
Immunocytochemical Diagnosis of Neoplastic Effusions of Unknown Origin Employing Selected Combinations of Monoclonal Antibodies to Tumor-Associated Antigens....Pages 237-240
Immunocytochemistry of Malignant Pleural Effusions in Breast Cancer....Pages 241-244
Monoclonal Antibodies OC125 and OV632 for the Diagnosis of Ovarian Cancer: A Comparative Immunocytochemical Study....Pages 245-249
Immunocytological Features of Malignant Ascites in Ovarian Carcinoma....Pages 250-252
Front Matter....Pages 253-253
Introduction....Pages 255-256
Transmission Electron Microscopy of Cytological Specimens....Pages 257-264
Ultrastructural Localization of Epithelial Membrane Antigen and Carcinoembryonic Antigen in Malignant Mesothelial and Epithelial Cells....Pages 265-273
Front Matter....Pages 253-253
On the Fine Structural Differential Diagnosis of Primary and Metastatic Lymph Node Tumors with Special Reference to the Nucleus....Pages 274-283
Immunologic Reactions on Cell Surfaces Investigated with Scanning and Transmission Electron Microscopy Using Replicas and Ultrathin Sections....Pages 284-288
Ultrastructure of Human Breast Carcinoma from a Pleural Effusion....Pages 289-292
Electron Microscopy in Childhood Tumors....Pages 293-297
Front Matter....Pages 299-299
Introduction....Pages 301-301
Reactive Cellular Changes in Soft Tissue....Pages 302-305
Reactive Changes of the Mesothelium....Pages 306-312
Reactive Cellular Changes: Pitfalls in Fine-Needle Aspirates from Reactive Lymph Nodes....Pages 313-319
Evaluation of Fine-Needle Aspiration Biopsy Findings in Treatment of Grave’s Disease....Pages 320-323
Cytological Monitoring of Human Hepatic Allografts....Pages 324-327
Front Matter....Pages 329-329
Cytology versus Histology in Carcinoma in Situ of the Breast and the Role of Fine-Needle Aspiration Cytology in the Treatment of Carcinoma in Situ....Pages 331-339
Comparison Between Fine-Needle Aspiration Cytology and Core Biopsy Histology in Prostatic Carcinoma....Pages 340-349
Technical Advances in Cell Collection as Applied to Prostatic Cytology....Pages 350-354
Transthoracic Fine-Needle Aspiration Cytology Guided by Fluoroscopy of Pulmonary Masses: Analysis of 460 Cases....Pages 355-358
Fine-Needle Aspirates of Nonpalpable Tumor Masses Guided by Computerized Tomography: Definition of Their Primary or Metastatic Nature Using Immunocytochemical Methods....Pages 359-364
Fine-Needle Aspiration in Ophthalmic Pathology....Pages 365-370
Cytological Diagnosis of Orbital and Periorbital Palpable Tumors....Pages 371-375
Routine and Special Staining in Cytology....Pages 376-382
Front Matter....Pages 383-383
Introduction....Pages 385-385
Experiences with a Nationwide Cancer Screening Programme for Cervical Cancer in the Federal Republic of Germany....Pages 386-391
Front Matter....Pages 383-383
Criteria for Evaluating the Screening Efficacy for Cervical Cancer: Estimated Sensitivity and Protective Effect of the Screening Program of Florence....Pages 392-398
Screening for Cervical Cancer — The Use of Epidemiological Studies to Evaluate Screening Policies....Pages 399-403
Evaluation of Cervical Smears in a Comparative Study Between Countries with Different Incidences of Cervical Cancer (Israel, Germany, South Africa)....Pages 404-407
Procedure for Validation of Mass Screening by Cervical Cytology....Pages 408-411
Significance of Cellular Composition of Smears for the Reliability of Cytological Diagnoses....Pages 412-420
Diagnostic Efficiency of Brush Cytology from the Uterine Cervix....Pages 421-424
Increase in Cervical Carcinoma in Situ in Young Women: Analysis of Screening General Practices 1974–1986....Pages 425-429
Screening for Breast Cancer....Pages 430-433
Early Detection of Lung Cancer Using Sputum Cytology....Pages 434-439
Bronchoalveolar Lavage T-Lymphocyte Subpopulations in Occupational and Non-occupational Lung Diseases....Pages 440-445
Back Matter....Pages 447-450