Neurotransmitters in Epilepsy. Epilepsy Research Supplements, Volume 8

Content: 
Front Matter, Page iii
Copyright, Page iv
Dedication, Page v, Franco Arosio
Foreword, Page vii, F.E. Dreifuss
Preface, Page ix, Giuliano Avanzini, Jerome Engel Jr., Ruggero Fariello, Uwe Heinemann
Acknowledgements, Page x
CHAPTER 1 - Historical Introduction: Early efforts to find neurochemical mechanisms in epilepsy, Pages 1-8, Herbert H. Jasper
CHAPTER 2 - Experimental animal models of epilepsy: classification and relevance to human epileptic phenomena, Pages 9-20, Jerome Engel Jr.
CHAPTER 3 - Neurotransmitter pharmacology of the epilepsies: discrepancies between animal models and human conditions, Pages 21-27, Ruggero G. Fariello, Douglas S. Garant
CHAPTER 4 - General Discussion Section I, Page 29
CHAPTER 5 - Functional alterations in GABAergic inhibition during activity, Pages 31-38, David A. Prince, Rudi A. Deisz, Scott M. Thompson, Yael Chagnac-Amitai
CHAPTER 6 - Blockade by (–)baclofen of recurrent inhibition in the guinea pig dentate gyrus in vitro, Pages 39-45, U. Misgeld
CHAPTER 7 - Sensitivity of chloride channels to changes in intracellular calcium: investigations on spontaneous and GABA-evoked activity, Pages 47-56, O. Taleb, P. Feltz, J.-L. Bossu, A. Feltz
CHAPTER 8 - Modulatory role of GABA receptor subtypes and glutamate receptors in the anticonvulsant effect of barbiturates, Pages 57-62, Maharaj K. Ticku, Shrinivas K. Kulkarni, Ashok K. Mehta
CHAPTER 9 - In vivo assessment of the importance of GABA in convulsant and anticonvulsant drug action, Pages 63-75, Robert M. Joy, Timothy E. Albertson
CHAPTER 10 - Involvement of GABA-dependent chloride channel in the action of anticonvulsant and convulsant drugs, Pages 77-85, A. Concas, M. Serra, E. Sanna, S. Pepitoni, M.P. Mascia, G. Biggio
CHAPTER 11 - Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD, Pages 87-96, R. Bernasconi, P. Martin, A.F. Steulet, C. Portet, T. Leonhardt, M. Schmutz
CHAPTER 12 - Age-dependent changes in substantia nigra GABA-mediated seizure suppression, Pages 97-106, Solomon L. Moshé, Ellen F. Sperber, Lucy L. Brown, Ann Tempel
CHAPTER 13 - GABA- and glutamate-containing neurons in the thalamus of rats and cats: an immunocytochemical study, Pages 107-115, R. Spreafico, S. De Biasi, G. Battaglia, A. Rustioni
CHAPTER 14 - Physiological properties of GABAergic thalamic reticular neurons studied in vitro: relevance to thalamocortical synchronizing mechanisms, Pages 117-124, Giuliano Avanzini, Marco de Curtis, Roberto Spreafico
CHAPTER 15 - Active role of cortical inhibition in the development of generalized epilepsy with spike-and-wave discharges: evidence from electrophysiological, microiontophoretic and simulation studies, Pages 125-133, George Kostopoulos, George Antoniadis
CHAPTER 16 - General discussion Section II, Pages 135-137
CHAPTER 17 - NMDA receptor involvement in epileptogenesis in the immature neocortex, Pages 139-145, John J. Hablitz, Wai-Ling Lee
CHAPTER 18 - Low-Ca2+-induced epileptiform activity in rat hippocampal slices, Pages 147-155, U. Heinemann, D. Albrecht, G. Köhr, G. Rausche, J. Stabel, T. Wisskirchen
CHAPTER 19 - The role of NMDA receptors in in vitro epileptogenesis, Pages 157-166, Wilkie A. Wilson, Steven Stasheff, Scott Swartzwelder, Suzanne Clark, William W. Anderson
CHAPTER 20 - Do NMDA antagonists suppress interictal discharges?, Pages 167-172, E. Cherubini, R. Neuman, Y. Ben-Ari
CHAPTER 21 - The entorhinal cortex and generation of seizure activity: studies of normal synaptic transmission and epileptogenesis in vitro, Pages 173-180, R.S.G. Jones, F.H. Heinemann, J.D.C. Lambert
CHAPTER 22 - Uncompetitive antagonist binding: a biochemical index of activation of the NMDA receptor-coupled ion channel, Pages 181-188, Douglas W. Bonhaus, James O. McNamara
CHAPTER 23 - Autoradiography and interaction of modulators of NMDA receptor activation, Pages 189-196, N.G. Bowery, G.W. Price, R. Ransom, E.H.F. Wong, A.E. Fletcher, G.P. Wilkin
CHAPTER 24 - Apparent desensitization to glutamate: possible role in epilepsy, Pages 197-201, Robert S. Fisher, Alison E. Cole
CHAPTER 25 - Relation between release of taurine and phosphoethanolamine and osmoregulation in experimental epilepsy, Pages 203-210, Anders Lehmann
CHAPTER 26 - Changes in the levels of glutamate and related amino acids in the intact and decorticated rat neostriatum during various conditions associated with convulsions, Pages 211-217, Bernt A. Engelsen, Frode Fonnum, Kjetil Furset
CHAPTER 27 - Pharmacological profile of novel cyclic analogs of 2-amino-7-phosphonoheptanoic acid, Pages 219-227, J.W. Ferkany, D.J. Kyle, W.P. Ellenberger, B.A. Narayanan, S.R. Ellenberger, R. Hudkins, M.E. Guzewska, W.J. Rzeszotarski, L. Conti, R. Patch, S.J. Enna
CHAPTER 28 - Amino acid neurotransmitter interactions in ‘area tempestas’: an epileptogenic trigger zone in the deep prepiriform cortex, Pages 229-234, K. Gale, P. Zhong, L.P. Miller, T.F. Murray
CHAPTER 29 - General discussion Section III, Pages 235-236
CHAPTER 30 - Interactions of adenosine and magnesium on neuronal excitability and transmitter sensitivity in the hippocampal slice, Pages 237-242, T.W. Stone, J.T. Bartrup, P.A. Brooks, J.H. Connick, D.A.S. Smith
CHAPTER 31 - Depression of burst discharges and of neuronal calcium influx by adenosine, Pages 243-253, Peter Schubert
CHAPTER 32 - A1 adenosine receptors express seizure-suppressant activity in the rat prepiriform cortex, Pages 255-261, T.F. Murray, P.H. Franklin, G. Zhang, E. Tripp
CHAPTER 33 - Two types of epileptic foci generating brief and sustained paroxysms in the in vitro rat hippocampus, Pages 263-269, Yoel Yaari, Morten S. Jensen
CHAPTER 34 - Fetal brain tissue grafts modulate neuronal excitability in a chronic model of epilepsy, Pages 271-281, György Buzsáki, Fred H. Gage
CHAPTER 35 - Brain amino acid concentrations during specific electroencephalographic stages of status epilepticus in the rat, Pages 283-294, David M. Treiman, Nancy Y. Walton, Sonny Gunawan
CHAPTER 36 - General discussion Section IV, Pages 295-296
CHAPTER 37 - Kindling increases brain levels of NAAG and seizures reduce activity of a NAAG-hydrolyzing enzyme, NAALADase, Pages 297-305, James L. Meyerhoff, Michael B. Robinson, Kerry J. Koller, Michael A. Bixler, Joseph T. Coyle
CHAPTER 38 - Recruitment of NMDA receptors into synaptic transmission after kindling-induced epilepsy and its possible mechanism, Pages 307-311, I. Mody, U. Heinemann, J.F. MacDonald, M.W. Salter
CHAPTER 39 - Synaptic and nonsynaptic determinants of excitability changes in aluminum-intoxicated rabbit CA1 pyramidal neurons studied in vitro, Pages 313-320, Silvana Franceschetti, Orso Bugiani, Ferruccio Panzica, Giuliano Avanzini
CHAPTER 40 - Noradrenergic modulation of excitability in acute and chronic model epilepsies, Pages 321-334, Patric K. Stanton, Istvan Mody, Daniel Zigmond, Terrence Sejnowski, Uwe Heinemann
CHAPTER 41 - Neurotransmission in rats' spontaneous generalized nonconvulsive epilepsy, Pages 335-343, C. Marescaux, M. Vergnes, A. Depaulis
CHAPTER 42 - Effect of intranigral muscimol on animal models of generalized absence seizures, Pages 345-350, O. Carter Snead III, A. Depaulis, M. Vergnes, C. Marescaux
CHAPTER 43 - In vivo interactions of pentylenetetrazole with benzodiazepine receptors: lack of direct correlation between benzodiazepine receptor occupancy and convulsant potency of this drug, Pages 351-359, C. Chavoix, E. Brouillet, Ph. Hantraye, V. de la Sayette, M. Kunimoto, M. Varastet, B. Guibert, R.H. Dodd, D. Fournier, R. Naquet, M. Mazière
CHAPTER 44 - N-methyl-D-aspartate-mediated responses in epileptic cortex in humans: an in-vitro study, Pages 361-367, J. Louvel, R. Pumain
CHAPTER 45 - Epileptogenesis and neuronal plasticity: studies on kainate receptor in the human and rat hippocampus, Pages 369-373, Y. Ben-Ari, E. Tremblay, O. Robain, G. LeGal LaSalle, C. Rovira, M. Gho, E. Cherubini, A. Represa
CHAPTER 46 - Extra- and intracellular amino acids in the CNS of patients with epilepsy and other neurological disorders, Pages 375-381, Anders Hamberger, Britta Nyström, Herbert Silfvenius
CHAPTER 47 - GABA/benzodiazepine receptors in human focal epilepsy, Pages 383-391, R.W. Olsen, M. Bureau, C.R. Houser, A.V. Delgado-Escueta, J.G. Richards, H. Möhler
CHAPTER 48 - General discussion Section V, Pages 393-395
Author index, Pages 397-398
Subject index, Pages 399-408