Neuroimmune Pharmacology

Front Matter....Pages i-xxxv
Front Matter....Pages 1-1
Innate and Adaptive Immunity in Health and Disease....Pages 3-4
The Blood-Brain Barriers....Pages 5-24
Regulation of Nervous System Function by Circumventricular Organs....Pages 25-37
Anterior Chamber and Retina (Structure, Function and Immunology)....Pages 39-54
The Vertebrate Retina....Pages 55-68
Hippocampus, Spatial Memory and Neuroimmunomodulation....Pages 69-79
Anatomical Networks: Structure and Function of the Nervous System....Pages 81-92
Immune Sensors and Effectors of Health and Disease....Pages 93-105
LRRK2....Pages 107-116
Astrocytes, Oligodendrocytes and Schwann Cells....Pages 117-140
Overview of Mononuclear Phagocytes....Pages 141-153
Macrophages, Microglia and Dendritic Cell Function....Pages 155-166
Microglial Biology and Physiology....Pages 167-199
Human Lymphocyte Biology and Its Application to Humanized Mice....Pages 201-216
Stem Cells and Neurogenesis for Brain Development, Degeneration and Therapy....Pages 217-243
Innate Immunity Signaling....Pages 245-260
Cytokines and Chemokines....Pages 261-283
Growth and Neurotrophic Factors in HIV-Associated Neurocognitive Disorders....Pages 285-298
RNA Binding Proteins in Health and Disease....Pages 299-312
Exosomes and Neuroregulation....Pages 313-328
Front Matter....Pages 1-1
MicroRNA Implications in Neurodegenerative Disorders....Pages 329-341
Front Matter....Pages 343-343
Neurodegeneration....Pages 345-354
Multiple Sclerosis....Pages 355-364
Guillain-Barré Syndrome, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, and Axonal Degeneration and Regeneration....Pages 365-372
Guillain-Barré Syndrome and Acute Neuropathy....Pages 373-393
Autoimmunity....Pages 395-406
HIV-Associated Neurocognitive Disorders....Pages 407-420
Neuroimmunomodulation of Human T-Lymphotrophic Virus Type I/II Infection....Pages 421-436
Viral Encephalitis....Pages 437-449
Alzheimer’s Disease....Pages 451-476
Parkinson’s Disease....Pages 477-492
Amyotrophic Lateral Sclerosis....Pages 493-502
Huntington’s Disease....Pages 503-516
Prion Diseases....Pages 517-531
Glaucoma....Pages 533-552
Ocular Manifestations of Systemic Autoimmune Diseases....Pages 553-573
Neurogenesis and Brain Repair....Pages 575-597
Chronic Traumatic Encephalopathy....Pages 599-620
The Neuroimmune System in Psychiatric Disorders....Pages 621-642
Autism Spectrum Disorders....Pages 643-659
Front Matter....Pages 343-343
Drugs of Abuse....Pages 661-678
Front Matter....Pages 679-679
Therapeutic Strategies in Neurodegenerative Diseases....Pages 681-711
Immunomodulatory Therapy for Multiple Sclerosis....Pages 713-736
Therapeutic Considerations in HIV-Associated Neurocognitive Disorders....Pages 737-751
Immunotherapy for Alzheimer’s Disease....Pages 753-766
Immunotherapies for Movement Disorders: Parkinson’s Disease and Amyotrophic Lateral Sclerosis....Pages 767-797
Regenerative and Repair Strategies for the Central Nervous System....Pages 799-818
New Generation of Adjuvants for Protection Against Disease and to Combat Bioterrorism....Pages 819-830
Medicinal Chemistry and Brain Drug Penetrance....Pages 831-845
Polymer Nanomaterials for Drug Delivery Across the Blood Brain Barrier....Pages 847-868
Macromolecular Therapeutics: Development and Delivery Engineering....Pages 869-883
Application to Gene Therapy and Vaccination....Pages 885-906
Introduction to Imaging in the Neurosciences....Pages 907-939
Proteomics and Genomics in Neuroimmunological Disorders....Pages 941-958
Pharmacogenomics of Neurodegenerative Diseases: Roles in Personalized Medicines....Pages 959-970
Control of Neuroinflammation for Therapeutic Gain....Pages 971-978
Back Matter....Pages 979-1035