Neurobiology of Essential Fatty Acids

Front Matter....Pages i-xi
The Induction of Cellular Group II Phospholipase A 2 by Cytokines and its Prevention by Dexamethasone....Pages 1-10
Brain Phospholipases And Their Role In Signal Transduction....Pages 11-25
Characteristics And Possible Functions of Mast Cell Phospholipases A 2 ....Pages 27-34
Extracellular Phospholipase A 2 ....Pages 35-39
Ischemic Brain Damage: Focus On Lipids And Lipid Mediators....Pages 41-56
Reciprocal Regulation of Fatty Acid Release In The Brain By Gaba and Glutamate....Pages 57-71
NMDA Receptor-Mediated Arachidonic Acid Release In Neurons: Role In Signal Transduction and Pathological Aspects....Pages 73-89
Non-Eicosanoid Functions of Essential Fatty Acids: Regulation of Adenosine-Related Functions In Cultured Neuroblastoma Cells....Pages 91-102
Contributions To Arachidonic Acid Release In Mouse Cerebrum by The Phosphoinositide-Phospholipase C and Phospholipase A 2 Pathways....Pages 103-114
Modulation of Arachidonic Acid Metabolism In Cultured Rat Astroglial Cells By Long-Chain N-3 Fatty Acids....Pages 115-120
Modulation of Glutamate Release From Hippocampal Mossy Fiber Nerve Endings By Arachidonic Acid And Eicosanoids....Pages 121-136
Metabotropic Glutamate Receptors and Neuronal Toxicity....Pages 137-145
A Role for The Arachidonic Acid Cascade In Fast Synaptic Modulation: Ion Channels and Transmitter Uptake Systems As Target Proteins....Pages 147-158
 Aplysia Californica Contains A Novel 12-Lipoxygenase which Generates Biologically Active Products From Arachidonic Acid....Pages 159-169
Essential Fatty Acid Deficiency In Cultured SK-N-SH Human Neuroblastoma Cells....Pages 171-182
Phospholipid Metabolism and Second Messenger System After Brain Ischemia....Pages 183-195
Impact of Dietary Fatty Acid Balance on Membrane Structure and Function of Neural Tissues....Pages 197-210
Structural and Functional Importance of Dietary Polyunsaturated Fatty Acids in the Nervous System....Pages 211-229
Long and Very Long Polyunsaturated Fatty Acids of Retina and Spermatozoa: The Whole Complement of Polyenoic Fatty Acid Series....Pages 231-242
Phospholipid Metabolism in Rat Intestinal Mucosa After Oral Administration of Lysophospholipids....Pages 243-249
Carbachol-Stimulated Release of Arachidonic Acid and Eicosanoids from Brain Cortex Synaptoneurosome Lipids of Adult and Aged Rats....Pages 251-258
Carbachol-Induced Stimulation of Inositol Phosphates, Arachidonic Acid and Prostaglandin F 2α in Rabbit Retina....Pages 259-265
Induced and Spontaneous Seizures in Man Produce Increases in Regional Brain Lipid Detected By in Vivo Proton Magnetic Resonance Spectroscopy....Pages 267-274
Network of Signal Transduction Pathways Involving Lipids: Protein Kinase C-Dependent and -Independent Pathways....Pages 275-284
Conservation of Docosahexaenoic Acid in the Retina....Pages 285-294
Docosahexaenoic Acid Uptake and Metabolism in Photoreceptors: Retinal Conservation By an Efficient Retinal Pigment Epithelial Cell-Mediated Recycling Process....Pages 295-306
Essential Fatty Acids and Neurodevelopmental Disorder....Pages 307-314
Regulation of Arachidonic Acid Metabolism in the Perinatal Brain During Development and Under Ischemic Stress....Pages 315-323
Interactions of Phospholipids and Free Fatty Acids with Antidepressant Recognition Binding Sites in Rat Brain....Pages 325-330
Very Long-Chain Fatty Acids in Peroxisomal Disease....Pages 331-340
Long Chain Omega 3 Polyunsaturates In Formula-Fed Term Infants....Pages 341-345
Severe Changes in Polyunsaturated Fatty Acids in the Brain, Liver, Kidney, and Retina in Patients with Peroxisomal Disorders....Pages 347-359
Degradation of Phospholipids and Protein Kinase C Activation for the Control of Neuronal Functions....Pages 361-373
Disposition Kinetics of Phospholipid Liposomes....Pages 375-391
Behavioral and Morpho-Functional Correlates of Brain Aging: A Preclinical Study with Phosphatidylserine....Pages 393-398
Receptor Coupling to Phosphoinositide Signals....Pages 399-411
Diacylglycerol Composition and Metabolism in Peripheral Nerve....Pages 413-425
Back Matter....Pages 427-444