Neurobiology of Disease

Contributors......Page 2
Editors......Page 9
Lysosomal Disorders of the Nervous System......Page 11
Neurobiology of Peroxisomal Disorders......Page 29
Creatine Deficiency Syndromes......Page 43
Leukodystrophies......Page 52
Parkinson's Disease......Page 59
Alzheimer's Disease......Page 76
Multiple System Atrophy......Page 90
Olivopontocerebellar Atrophy (OPCA)......Page 101
Neurobiology of Progressive
Supranuclear Palsy......Page 111
Protein Aggregation
Disorders......Page 117
RNA-Based Disorders of
Muscle and Brain......Page 130
Ion Channel Disorders......Page 139
Spinocerebellar Ataxia
Type 1......Page 153
Mitochondrial Genetic
Diseases......Page 160
Paraneoplastic Neurological
Disorders......Page 165
Systemic Lupus
Erythematosus: Descriptive
Past and Mechanistic Future......Page 172
Progressive Multifocal
Leukoencephalopathy......Page 186
Immunopathogenesis of
Multiple Sclerosis......Page 197
Immune-Mediated
Neuropathies......Page 205
Hashimoto Encephalopathy......Page 216
Vascular Cognitive
Impairment......Page 221
Cardioembolism......Page 232
Clinical and Neurobiological
Aspects of Stroke Recovery......Page 238
Nonatherosclerotic Cerebral
Vasculopathies......Page 251
Subarachnoid Hemorrhage......Page 260
Cerebral Ischemia:
Molecular Mechanisms and
Protective Therapies......Page 266
Intracerebral Hemorrhage
and Intraventricular
Hemorrhage–Induced Brain
Injury......Page 275
Idiopathic Generalized
Epilepsy......Page 282
Paroxysmal Dyskinesia......Page 290
Myoclonus......Page 298
Channelopathies of the
Nervous System......Page 311
Migraine as a Cerebral
Ionopathy with Abnormal
Central Sensory Processing......Page 325
Temporal Lobe Epilepsy......Page 341
Central Nervous System
Metastases......Page 362
Meningioma......Page 371
Primary Central Nervous
System Lymphoma......Page 384
Neurofibromatosis 1......Page 402
Medulloblastoma and
Primitive Neuroectodermal
Tumors......Page 413
Glioma......Page 421
Bacterial and Fungal
Infections of the Nervous
System......Page 433
Parasitic Infections......Page 440
Prion Diseases......Page 460
Central Nervous System
Viral Infections: Clinical
Aspects and Pathogenic
Mechanisms......Page 471
Spinal Muscular Atrophy......Page 486
Amyotrophic Lateral
Sclerosis–Like Syndromes
Associated with Malignancy......Page 497
Amyotrophic Lateral
Sclerosis: Idiopathic and
Inherited......Page 504
Hereditary Spastic
Paraplegia and Primary
Lateral Sclerosis......Page 519
Poliomyelitis......Page 527
Spinobulbar Muscular
Atrophy (Kennedy’s
Disease)......Page 534
Neurobiology of Genetic
Mental Retardation......Page 543
Cerebral Palsy......Page 554
Autism......Page 560
Neurobiology of Dyslexia......Page 571
Neonatal Brain Injuries......Page 577
Spina Bifida......Page 588
Circuits to Synapses: The
Pathophysiology of Tourette
Syndrome......Page 596
Attention-Deficit
Hyperactivity Disorder......Page 608
Congenital Hydrocephalus......Page 617
Neurological Manifestations
of Hematological Disease......Page 624
Neurological Manifestations
of Renal Disease......Page 634
Diabetes and Endocrine
Disorders......Page 643
Mechanisms and
Consequences of Central
Nervous System Hypoxia......Page 655
Neurological Manifestations
of Gastrointestinal and
Hepatic Diseases......Page 663
Neurosarcoidosis......Page 676
REM Sleep Behavior
Disorder......Page 681
Neurobiology of Narcolepsy
and Hypersomnia......Page 687
Restless Legs Syndrome
and Periodic Limb
Movements in Sleep......Page 695
Neurobiology of Insomnia......Page 706
Organic Chemicals......Page 716
Metals......Page 730
Neurobiology of Drug
Addiction......Page 741
Assessment of
Neurobiological Diseases
with Magnetic Resonance
Spectroscopy......Page 750
Magnetic Resonance
Imaging......Page 762
Neurovascular Computed
Tomography Angiography......Page 770
PET Imaging in Parkinson’s
Disease and Other
Neurodegenerative
Disorders......Page 789
Single-Photon Emission
Computed Tomography......Page 797
Functional Magnetic
Resonance Imaging......Page 806
Impaired Glucose
Regulation and Neuropathy......Page 816
Acquired Inflammatory
Demyelinating and Axonal
Neuropathies......Page 826
Toxic and Drug-Induced
Neuropathies......Page 837
Inherited Peripheral
Neuropathies......Page 850
Neurological Manifestations
of Vasculitis......Page 865
Neuropathies Associated
with Infections......Page 876
Muscular Dystrophies......Page 888
Myasthenia Gravis and
Myasthenic Syndromes......Page 898
Metabolic Myopathies......Page 910
Immunobiology of
Autoimmune Inflammatory
Myopathies......Page 920
Central Autonomic Network......Page 932
Autonomic Neuropathies......Page 941
Thermoregulation and
Its Disorders......Page 949
Control of Blood
Pressure—Normal
and Abnormal......Page 959
Neoplasm-Induced Pain......Page 968
Pain Associated with the
Autonomic Nervous System......Page 982
Postherpetic Neuralgia......Page 992
Central Post-Stroke Pain......Page 999
index......Page 1007