Nephrotoxicity in the experimental and clinical situation: Part 1

Front Matter....Pages i-xi
Fixation of Renal Tissue for Cytochemical Evaluation....Pages 1-17
The Application of Histochemistry at the Light Microscopic Level to the Study of Nephrotoxicity....Pages 19-84
Cryomicrotomy of Renal Tissue, and the Use of X-Ray Microanalysis and Autoradiography at the Light and Electron Microscopic Levels....Pages 85-139
Fixation of Kidney Tissue for Morphometric Study....Pages 141-166
Correlating Structural and Functional Changes in Nephrotoxic Renal Injury....Pages 167-188
Naturally Occurring Renal Disease in Non-Human Primates....Pages 189-210
Chemically Induced Epithelial Tumours and Carcinogenesis of the Renal Parenchyma....Pages 211-250
Assessment of the Kidney in Relation to Blood Pressure Regulation....Pages 251-300
Renal Slices and Perfusion....Pages 301-316
The Use of Single Nephron Techniques in Renal Toxicity Studies....Pages 317-358
Prostaglandins and Other Eicosanoids....Pages 359-370
Xenobiotic Metabolism in the Mammalian Kidney....Pages 371-404
Metabolism of Glutathione in the Kidney....Pages 405-428
Metabolic Activation of Halogenated Chemicals and its Relevance to Nephrotoxicity....Pages 429-461
Back Matter....Pages xiii-xxxi