Nano-Biomaterials For Ophthalmic Drug Delivery

Front Matter....Pages i-xix
Introduction to Nanotechnology with Special Reference to Ophthalmic Delivery....Pages 1-8
Overview of the Ophthalmic System....Pages 9-36
Pharmacological Considerations in Ophthalmic Drug Delivery....Pages 37-56
Pathophysiology of Vision....Pages 57-81
Nanotechnology and Nanomaterials in Ophthalmic Drug Delivery....Pages 83-109
Pharmacokinetics and Pharmacodynamics of Ocular Drugs....Pages 111-129
Physicochemical Requirements for Polymers and Polymer-Based Nanomaterial for Ophthalmic Drug Delivery....Pages 131-146
Formulation Approaches for Ocular Drug Delivery....Pages 147-175
Ocular Permeation Enhancers....Pages 177-209
Ocular Bioadhesives and Their Applications in Ophthalmic Drug Delivery....Pages 211-230
Nanovesicular Carrier Systems for Ophthalmic Drug Delivery....Pages 231-242
Cyclodextrins in Ocular Drug Delivery....Pages 243-252
Ocular Preservatives: Risks and Recent Trends in Its Application in Ocular Drug Delivery (ODD)....Pages 253-276
Aging Disorders of the Eye: Challenges and Approaches for Their Treatment....Pages 277-320
Colloidal Carriers in Ophthalmic Drug Delivery....Pages 321-349
Polymeric Nanoparticulate Systems: A Potential Approach for Ocular Drug Delivery....Pages 351-387
Barriers to Glaucoma Drug Delivery and Resolving the Challenges Using Nanotechnology....Pages 389-406
Intraocular Drug Delivery Technologies: Advancing Treatment of Posterior Segment Disorders of the Eye....Pages 407-460
Animal Models to Evaluate Nanoparticulate Ocular Drug Delivery Systems....Pages 461-469
Ophthalmic Nanosuspensions: Toxicity and Formulation....Pages 471-481
Ocular Drug Delivery: Impact of In Vitro Cell Culture Models....Pages 483-494
Nanotoxicity of Nanobiomaterials in Ocular System and Its Evaluation....Pages 495-533
Nanosystem in Ocular Bioenvironment....Pages 535-553
Excipients Utilized for Ophthalmic Drug Delivery Systems....Pages 555-582
Ophthalmic Drug Delivery Systems for the Treatment of Corneal Diseases....Pages 583-592
Challenges in Ocular Pharmacokinetics and Drug Delivery....Pages 593-611
Back Matter....Pages 613-627