Moving Questions: A History of Membrane Transport and Bioenergetics

Front Matter....Pages i-1
Introduction....Pages 3-12
Views in the 1930s....Pages 13-25
Accounting for Asymmetric Distributions of Na + and K + in Muscle....Pages 26-52
Accounting for Asymmetric Distributions of Na + and K + in Red Blood Cells....Pages 53-67
Ion Gradients and Movements in Excitable Tissues....Pages 68-88
Epithelial Transport by Frog Skin....Pages 89-97
Contemporary Events: 1939–1952....Pages 98-102
Characterizing the Na + /K + Pump....Pages 103-125
Identifying the Na + /K + -ATPase....Pages 126-146
Contemporary Events: 1953–1965....Pages 147-155
Characterizing the Na + /K + -ATPase....Pages 156-182
Structure and Relatives of the Na + /K + -ATPase....Pages 183-204
Alternatives....Pages 205-219
Using the Transmembrane Cation Gradients: Transporters and Channels....Pages 220-237
Contemporary Events: 1966–1985....Pages 238-246
Oxidative Phosphorylation: Chemical-Coupling Hypothesis....Pages 247-260
Oxidative Phosphorylation: Chemiosmotic Coupling Hypothesis....Pages 261-282
Oxidative Phosphorylation: F 1 , F 0 F 1 , and ATP Synthase....Pages 283-299
Conclusions....Pages 300-311
Back Matter....Pages 312-373