Morphological and Functional Aspects of Immunity: Proceedings of the Third International Conference on Lymphatic Tissue and Germinal Centers held in Uppsala, Sweden, September 1–4, 1970

Front Matter....Pages i-xxvii
New Observations on Lymph Gland (LM1) and Thymus Activity in Larval Bullfrogs, Rana Catesbeiana ....Pages 1-10
The Use of Surface Alloantigenic Markers to Study the Differentiation of Thymus-Derived Lymphocytes in Mice....Pages 11-15
A New Theoretical Model of Plasma Cell Differentiation....Pages 17-24
The Rabbit Appendix: A Central or Peripheral Lymphoid Organ?....Pages 25-30
Immunoglobulin Gene Expression in Immunocyte Differentiation....Pages 31-36
The Maturation of Lymphoid Tissue Structure and Function in Ontogeny....Pages 37-42
Discussion to Session 1....Pages 43-49
Studies on the Transfer of Natural E. Coli Antibody Production in Rats....Pages 51-56
Lymphoid Cells Reacting against ‘Self’ and their Possible Role in Immune Responses....Pages 57-62
In Vitro Interaction between Bone Marrow-Derived and Thymus Cells....Pages 63-68
Cell Interactions in the In Vitro Production of Antibodies to Chemically Defined Antigens....Pages 69-80
Origin and Interaction of Imunologically Active Cells....Pages 81-85
Discussion to Session 2....Pages 87-91
Interaction between T Cells and B Cells in Humoral Antibody Responses....Pages 93-102
Quantitative Studies of Thymocytokinetics....Pages 103-112
Migration of Thymic Lymphocytes: Immunofluorescence and 3 HTdR Labeling Studies....Pages 113-118
Homing of Cells from the Bursa of Fabricius to Germinal Centers in the Chicken Spleen....Pages 119-128
Immune Competence of Cells Derived from Hemopoietic Liver after Traffic to Thymus....Pages 129-133
The Fate of Lymph-Borne Immunoblasts....Pages 135-140
Massive Migration of Thymic Lymphocytes to Peyer’s Patches in Neonatal Mice....Pages 141-147
Lymphoid Cell Migration....Pages 149-159
Discussion to Session 3....Pages 161-167
Histological Changes of Lymphoid Tissues in Relation to the Ontogeny of the Immune Response in Germfree Piglets....Pages 169-177
Sites of Specific Antibody Production after Injection of Human Serum Albumin (HSA) in Complete Freund-type Adjuvant in the Chicken....Pages 179-186
Fate and Immunogenicity of Antigens Endocytosed by Macrophages....Pages 187-195
Cellular and Immunological Events Following Injection of Antigen into the Chicken Thymus....Pages 197-201
Lymphatic Tissue and Germinal Centers in Relation to Antibody Production....Pages 203-212
Discussion to Session 4....Pages 213-219
The Mechanism of Antigen Localization in Lymphoid Follicles and the Patterns of Localization of Tolerance-Inducing Flagellar Proteins....Pages 221-225
Accelerated and Enhanced Germinal Center Development in Regional Lymph Nodes of Mice Following Primary Stimulation with Antigen-Antibody Complexes as Compared to Antigen Only....Pages 227-234
Lymph Node Response to Antigen-Antibody Complexes and the Fate of Injected Primed Lymphocytes in a Tolerant Host....Pages 235-241
Mechanism of Interaction between Immune Complexes and Receptors for Antibody on Macrophages....Pages 243-249
Follicular Localization of Antigen: Possible Role of Lymphocytes Bearing a Receptor for Antigen-Antibody-Complement Complexes....Pages 251-256
Localization of Antigen and Immune Complexes in Lymphatic Tissue, with Special Reference to Germinal Centers....Pages 257-279
Discussion to Session 5....Pages 281-287
Role of Inductive Microenvironments on Hemopoietic (and Lymphoid?) Differentiation, and Role of Thymic Cells in the Eosinophilic Granulocyte Response to Antigen....Pages 289-298
An In Vitro Model System for the Study of the Induction of Cellular Immunity....Pages 299-307
Primary Immune Reaction of Allogeneic Lymph Node Cells against Tissue Antigens of Lethally Irradiated Hosts....Pages 309-314
An Alternative Model of Antibody Forming Cell Differentiation....Pages 315-322
A Quantitative Model for the Mechanism of Antibody Formation and Tolerance....Pages 323-331
Modelling of the Immune Processes....Pages 333-349
Discussion to Session 6....Pages 351-363
Attempt to Separate Antibody-Forming Clones of Different Affinity for One Antigenic Determinant on a Macromolecule....Pages 365-369
Cellular Immunity in Vitro : Specific Antigen Induces Sensitization and Activates a Nonspecific Cytolytic Effect....Pages 371-378
Control of Lymphocyte Growth in Response to Phytohemgglutinin Stimulation....Pages 379-386
Studies of the Mechanism of Prevention of Immunologic Deficiency in Suckling Dwarf Mice....Pages 387-393
The Regulation of Antibody Formation....Pages 395-402
Discussion to Session 7....Pages 403-412
A Quantitative Assessment of Cellular Recovery in Lymphoid Tissue....Pages 413-420
A Study of the Properties and Effects of Anti-Macrophage Sera....Pages 421-427
Effect of L-Asparaginase on Thymus-Dependent Immune Reactivity....Pages 429-434
The Ultrastructure of Antibody-Forming Spleen Cells in Immunologically Suppressed Leukemic Mice....Pages 435-444
Effects of Antilymphocyte Serum on the Localization of 125 I-Labeled Flagella, Colloidal Carbon, and Titanium Dioxide in Splenic Lymphoid Follicles....Pages 445-449
Electron Microscopic Observations in Rat Lymph Nodes Following Injection of AMS and ATS....Pages 451-453
Modification of the Immune Response by External Agents. An Introduction to the Discussion....Pages 455-459
Discussion to Session 8....Pages 461-466
Surface Antigens of Immunocompetent Cells....Pages 467-480
The Side Effects of High Zone Tolerance....Pages 481-486
The Mechanism of Breakdown of Immune Tolerance to Protein Antigen in Rabbits....Pages 487-491
Presence of Antigen Binding Cells in Mice Tolerant to E. Coli Polysaccharide....Pages 493-498
Cellular and Humoral Aspects of “High and Low Dose” Tolerance to Sheep Erythrocytes in Mice....Pages 499-506
Comparative Studies of Antigen Injected into Adults and Neonatal Rabbits....Pages 507-519
Induction and Termination of Immunological Unresponsiveness....Pages 521-526
Discussion to Session 9....Pages 527-532
Immunological Reactivity of Mice Injected with Leukaemic Cells....Pages 533-538
In Vitro Immunization for Immunotherapy....Pages 539-544
Cellular Immunity, Its Serum Mediated Inhibition and Tumor-Distinctive Anergy to Tumors in Man....Pages 545-553
Tumor Induction by Murine Leukemia/Sarcoma Viruses: Morphological and Immunological Studies....Pages 555-565
Factors Contributing to the “Success” of Antigenic Tumours....Pages 567-574
Discussion to Session 10....Pages 575-582
Lymphofollicular Hyperplastic Responses in Ectopic Locations: Trachoma as a Paradigm....Pages 583-594
The Bone Marrow Origin of Lymphoid Primary Follicle Small Lymphocytes....Pages 595-602
Effect of Partial Hepatectomy on Immune Responses II. Enhancing Effect on Antigen Primed Lymphocytes....Pages 603-608
Regulation of the Immune Response. IV. The Role of the Fc-Fragment in Feedback Inhibition by Antibody....Pages 609-615
The Role of the Bursa of Fabricius in the Recovery from Immunologic Tolerance to Bovine Serum Albumin....Pages 617-620
Cell Destructive Action of Phytohaemagglutinin (PHA)-Stimulated Human Lymphocytes; Studies on the Mechanism of this Cytoaggressive effect in Vitro....Pages 621-624
On the Mechanism of Germinal Center Formation....Pages 625-627
Appendix and Bone Marrow Cell Synergism in Early Antibody Response to Sheep Erythrocytes....Pages 629-631
Thymus-Marrow Cell Interaction In Vitro ....Pages 633-640
Migration, Recirculation and Transformation of Large Dividing Lymph Node Cells in Syngeneic Recipient Rats Following Intravenous Injection....Pages 641-643
Immunosuppression by L-Asparaginase....Pages 645-648
Immunosuppressive Properties and Side Effects of E. Coli L-Asparaginase....Pages 649-653
Chronic Histoincompatibility and Lymphomagetosis in Mice....Pages 655-665
Immunological Effects of Cortisone Caused by Interference with Lymphoid Cell Traffic....Pages 667-672
Immunological Unresponsiveness to Soluble Antigens in Adult Mice....Pages 673-678
The Immobilization of Lymphoid Cells in the Developing Palatine Tonsil of the Rabbit....Pages 679-681
Back Matter....Pages 683-694