Molecular Pathology of Hematolymphoid Diseases

Front Matter....Pages i-xv
Front Matter....Pages 1-1
Molecular Oncogenesis....Pages 3-19
Genetic Predispositions for Hematologic and Lymphoid Disorders....Pages 21-64
Prognostic Markers....Pages 65-72
Cancer Stem Cells: Potential Targets for Molecular Medicine....Pages 73-80
Gene Therapy for Leukemia and Lymphoma....Pages 81-89
Chemical and Environmental Agents (Including Chemotherapeutic Agents and Immunosuppression)....Pages 91-106
Viral Oncogenesis....Pages 107-116
Front Matter....Pages 118-118
Techniques to Determine Clonality in Hematolymphoid Malignancies....Pages 119-128
Techniques to Detect Defining Chromosomal Translocations/Abnormalities....Pages 129-152
Molecular Techniques to Detect Disease and Response to Therapy: Minimal Residual Disease....Pages 153-164
Detection of Resistance to Therapy in Hematolymphoid Neoplasms....Pages 165-171
Monitoring Engraftment of Bone Marrow Transplant by DNA Fingerprinting....Pages 173-176
Gene Expression Profiling....Pages 177-189
Proteomics of Human Malignant Lymphoma....Pages 191-202
Mouse Models of Hematolymphoid Malignancies....Pages 203-208
Front Matter....Pages 210-210
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma....Pages 211-220
Marginal Zone B-Cell Lymphoma....Pages 221-231
Lymphoplasmacytic Lymphoma....Pages 233-239
Molecular Pathology of Plasma Cell Neoplasms....Pages 241-247
The Roles of Molecular Techniques in the Diagnosis and Management of Follicular Lymphoma....Pages 249-255
Front Matter....Pages 210-210
Mantle Cell Lymphoma....Pages 257-265
Diffuse Large B-Cell Lymphomas....Pages 267-276
The Molecular Pathology of Burkitt Lymphoma....Pages 277-285
Precursor B-Cell Acute Lymphoblastic Leukemia....Pages 287-307
Molecular Genetics of Mature T/NK Neoplasms....Pages 309-327
Precursor T-Cell Neoplasms....Pages 329-346
Classical Hodgkin Lymphoma and Nodular Lymphocyte Predominant Hodgkin Lymphoma....Pages 347-358
Posttransplant Lymphoproliferative Disorder....Pages 359-365
AIDS-Related Lymphomas....Pages 367-385
Chronic Myelogenous Leukemia....Pages 387-394
Molecular Pathogenesis of Nonchronic Myeloid Leukemia Myeloproliferative Neoplasms....Pages 395-403
Molecular Pathology of Myelodysplastic/Myeloproliferative Neoplasms, Myeloid and Lymphoid Neoplasms with Eosinophilia and Abnormalities of PDGFRA, PDGFRB, and FGFR1, and Mastocytosis....Pages 405-416
Molecular Pathogenesis of Myelodysplastic Syndromes....Pages 417-427
Acute Myeloid Leukemias with Recurrent Cytogenetic Abnormalities....Pages 429-448
Acute Myeloid Leukemias with Normal Cytogenetics....Pages 449-462
Acute Myeloid Leukemia with Myelodysplasia-Related Changes and Therapy-Related Acute Myeloid Leukemia....Pages 463-471
Molecular Pathology of Hemoglobin and Erythrocyte Membrane Disorders....Pages 473-497
White Blood Cell and Immunodeficiency Disorders....Pages 499-509
Molecular Basis of Disorders of Hemostasis and Thrombosis....Pages 511-528
Sarcoidosis: Are There Sarcoidosis Genes?....Pages 529-539
Front Matter....Pages 210-210
Castleman’s Disease....Pages 541-544
Molecular Pathology of Histiocytic Disorders....Pages 545-560
Reactive Lymphadenopathies: Molecular Analysis....Pages 561-567
Molecular Pathology of Infectious Lymphadenitides....Pages 569-595
Gene Therapy for Nonneoplastic Hematologic and Histiocytic Disorders....Pages 597-608
Back Matter....Pages 609-625