Molecular Mechanisms of Membrane Traffic

Front Matter....Pages I-XIII
Cell-Free Analysis of ER to Golgi Apparatus Vesicular Traffic....Pages 1-15
Identification of a Novel Post-ER, Pre-Golgi Compartment Where Unassembled Monomers of Oligomeric Proteins Accumulate....Pages 17-34
G Protein Regulation of Vesicular Transport Through the Exocytic Pathway....Pages 35-44
Fusion Rapidly Follows Vesicle Transport to the Target Membrane in Protein Transport through the Golgi Apparatus in Vitro . A Re-evaluation of Transport Kinetics Based on the Finding that the Glycosylation Used to Mark Transport, and Not Transport Itself, is Rate Limiting in the Assay....Pages 45-51
Immunocytochemical analysis of the transfer of vesicular stomatitis virus G glycoprotein from the intermediate compartment to the Golgi complex....Pages 53-54
Synthesis of Glycosyl-Phosphatidylinositol Anchors is Initiated in the Endoplasmic Reticulum....Pages 55-56
Protein Trafficking along the Exocytotic Pathway....Pages 57-58
A Short N-Terminal Sequence is Responsible for the Retention of Invariant Chain (Ii) in the Endoplasmic Reticulum....Pages 59-60
Isolation and characterization of the principal ATPase of transitional elements of the endoplasmic reticulum of rat liver....Pages 61-62
A GTP Hydrolase Activity Purified from Transitional Endoplasmic Reticulum of Rat Liver Binds Retinol....Pages 63-64
A 38 kDa Protein Resident to CIS Golgi Apparatus Cisternae of Rat Liver is Recognized by an Antibody Directed Against α Subunits of Trimeric G-Proteins....Pages 65-66
Acyl Transfer Reactions Associated with Cis Golgi Apparatus....Pages 67-68
Hepatic Bile Formation: Intracellular Trafficking of Bile Salts....Pages 69-70
Wheat storage proteins as a model system to study the mechanism of protein sorting within the endoplasmic reticulum....Pages 71-72
Determinants of Outer Membrane Protein Sorting and Topology in Mitochondria....Pages 73-79
Molecular Chaperones HSP70 and HSP60 in Protein Folding and Membrane Translocation....Pages 81-90
Cytosolic Reactions in Mitochondrial Protein Import....Pages 91-94
Human Bifunctional Enzyme and Its Import into Peroxisomes....Pages 95-98
Transport of Microinjected Proteins into the Peroxisomes of Mammalian Cells....Pages 99-100
Isolation And Characterization Of A Functionally Active Protein Translocation Apparatus From Chloroplast Envelopes....Pages 101-104
Protein Insertion Into The Outer Mitochondrial Membrane....Pages 105-106
The Membrane-Bound 95 KDA Subunit of the Yeast Vacuolar Proton-Pumping ATPase is Required for Enzyme Assembly and Activity....Pages 107-108
The Traffic of Molecules Across the Tonoplast of Plant Cells....Pages 109-110
Fusicoccin Binding and Internalization by Soybean Protoplasts....Pages 111-112
TGN38 and Small GTP Binding Proteins are Part of a Macromolecular Complex in the Trans-Golgi Network....Pages 113-116
β-COP, a Coat Protein of Nonclathrin-Coated Vesicles of the Golgi Complex, is Involved in Transport of Vesicular Stomatitis Virus Glycoprotein....Pages 117-126
Defining the Retention Signal in a Model Golgi Membrane Protein....Pages 127-133
Organization of the Glycoprotein and Polysaccharide Synthetic Pathways in the Plant Golgi Apparatus....Pages 135-144
CLIP-170, a Cytoplasmic Linker Protein Mediating Interaction of Endosomes with Microtubules....Pages 145-157
Maturation of Secretory Granules....Pages 159-162
Fatty Acylation in Membrane Trafficking and During Mitosis....Pages 163-166
Rates of Synthesis and Selective Loss into the Bile of Four Rat Liver Proteins and the Polymeric IgA Receptor....Pages 167-170
Effect of Brefeldin A Treatment on the Resident Golgi Protein, MG160....Pages 171-172
Inhibition of Cholera Toxin by Brefeldin A....Pages 173-174
Selective Association with Golgi of ADP-Ribosylation Factors, 20-kDa Guanine Nucleotide-Binding Protein Activators of Cholera Toxin....Pages 175-176
Intracellular Transport and Post-Translational Modifications of a Secretory Heat Shock Protein of Saccharomyces Cerevisiae ....Pages 177-178
Transport to the Cell Surface of Chlamydomonas : Mastigonemes as a Marker for the Flagellar Membrane....Pages 179-180
Lipid Transport from the Golgi to the Plasma Membrane of Epithelial Cells....Pages 181-185
Lipid Traffic to the Plasma Membrane of Leek Cells. Sorting Based on Fatty Acyl Chain Length....Pages 187-195
Hexadecylphosphocholine as an Useful Tool for Investigating Phosphatidylcholine Biosynthesis and Sorting....Pages 197-198
Biosynthesis of the Scrapie Prion Protein in Scrapie-Infected Cells....Pages 199-200
Protein Phosphorylation Regulates the Cellular Trafficking and Processing of the Alzheimer Beta/A4 Amyloid Precursor Protein....Pages 201-202
Targeting of the Polymeric Immunoglobulin Receptor in Transfected PC12 Cells....Pages 203-204
Signals for Receptor-Mediated Endocytosis....Pages 205-214
Regulation of Early Endosome Fusion In Vitro....Pages 215-228
Adaptins and their Role in Clathrin-Mediated Vesicle Sorting....Pages 229-236
Endosomes and Cell Signalling....Pages 237-244
The Tubular Early Endosome....Pages 245-267
Direct Comparision of the Endocytic Routes of Fluorescently-Labelled Lipids and Transferrin....Pages 269-272
Linkage of Plasma Membrane Proteins with the Membrane Skeleton: Insights into Functions in Polarized Epithelial Cells....Pages 273-283
Cell Specificity and Developmental Variation in the Targeting Pathways of FRT Cells....Pages 285-288
Phosphoglucomutase is a Cytoplasmic Glycoprotein Implicated in the Regulated Secretory Pathway....Pages 289-292
Protein Targeting and the Control Of C1 − Secretion in Colonic Epithelial Cells....Pages 293-296
Apical Membrane Protein Sorting is Affected by Brefeldin A....Pages 297-299
Structural Analysis of the Clathrin Triskelion....Pages 301-305
Polarity in Neurons and Epithelial Cells : Distribution of Endogenous and Exogenous Ion Pumps and Transporters....Pages 307-308
Biochemical Properties and Expression of Tau Proteins in the Endocytic Compartment during Liver Regeneration....Pages 309-310
Identification of Hepatic Endocytic Proteins Potentially Involved in Membrane Traffic....Pages 311-312
Studies on Sequence Requirements for Basolateral Targeting of the Polymeric Immunoglobulin Receptor in MDCK Cells....Pages 313-314
Endocytosis by Trypanosoma Brucei : Proteases and Their Possible Role in the Degradation of Anti-VSG Antibodies....Pages 315-316
Receptor Mediated Endocytosis of EGF in a Cell Free System....Pages 317-318
Transferrin on the Basolateral Surface Regulates Apical 59 Fe Uptake and Transport Across Intestinal Epithelial Cells....Pages 319-320
Intracellular Trafficking of Salmonella Typhimurium within HeLa Epithelial Cells....Pages 321-322
Functional Analysis of Dynamin, a GTPase Mediating Early Endocytosis....Pages 323-324
Identification of a Regulatory Domain in Dynamin....Pages 325-326
Potassium Depletion Stimulates Clathrin-Independent Endocytosis in Rat Foetal Fibroblasts....Pages 327-328
Clathrin Interaction with NADH Dehydrogenases of Rat Liver Plasma Membrane....Pages 329-330
Putative Adaptor Proteins of Clathrin Coated Vesicles from Developing Pea....Pages 331-332
Uncoating of Plant Clathrin Coated Vesicles by Uncoating ATPase from Peas....Pages 333-334
Selective Degradation of Cytosolic Proteins by Lysosomes....Pages 335-338
Role of Calcium, Protein Phosphorylation and the Cytoskeleton in Hepatocytic Autophagy....Pages 339-349
Signals for Transport from Endosomes to Lysosomes....Pages 351-358
A New Receptor for Lysosomal Proenzymes....Pages 359-362
A Protein Kinase/Lipid Kinase Complex Required for Yeast Vacuolar Protein Sorting....Pages 363-366
The Morphology but Not the Function of Endosomes and Lysosomes is Affected by Brefeldin A....Pages 367-370
Purification of the N-Acetylglucosamine-1-Phosphodiester α-N-Acetylglucosamindase from Human Lymphoblasts....Pages 371-372
Altered Regulation of Protein Degradation in Transformed Human Bronchial Epithelial Cells....Pages 373-374
An Examination of the Structure and Functions of the Bovine Vacuolar ATPase Using Antisense Oligonucleotides....Pages 375-376
Regulation of Endocytosis by the Small GTP-ASE RAB5....Pages 377-385
The Nucleotide Cycle of Sec4 is Important for Its Function in Vesicular Transport....Pages 387-390
Activators of Trimeric G-Proteins Stimulate and Inhibit Intercompartmental Golgi Transport in Vitro ....Pages 391-394
Evidence of a Role for Heterotrimeric GTP-binding Proteins and ARF in Endosome Fusion....Pages 395-398
The Small GTPase Rab4 Controls an Early Endocytic Sorting Event....Pages 399-402
Protein Modifications and Their Significance in rab5 Function....Pages 403-404
Low Molecular Weight GTP-binding Proteins in Rough Endoplasmic Reticulum Membranes from Rat Liver and Rat Hepatocellular Carcinomas....Pages 405-407
Low Molecular Weight GTP-binding Proteins Associated with the Membranes Involved in Post-Golgi Transport of Rhodopsin....Pages 408-408
Back Matter....Pages 409-418